Results 101 to 110 of about 28,018 (244)

Intramedullary Spinal Cord Ependymoma after Posterior Fossa Ependymoma Resection: A Case Report

Nepal Journal of Neuroscience, 2016
We experienced a case in which multiple spinal cord dissemination was found 6 years after resection of the fourth ventricle ependymoma. A 17-year-old boy had undergone a subtotal resection of the fourth ventricle ependymoma and radiation therapy to the ...
Benju R Pradhan , Bal K Thapa
doaj   +1 more source

Immunohistochemical analysis of H3K27me3 demonstrates global reduction in group-A childhood posterior fossa ependymoma and is a powerful predictor of outcome

Acta Neuropathologica, 2017
Posterior fossa ependymomas (EPN_PF) in children comprise two morphologically identical, but biologically distinct tumor entities. Group-A (EPN_PFA) tumors have a poor prognosis and require intensive therapy. In contrast, group-B tumors (EPN_PFB) exhibit
Pooja Panwalkar, Jonathan Clark, V. Ramaswamy, D. Hawes, Fusheng Yang, C. Dunham, S. Yip, J. Hukin, Yilun Sun, M. Schipper, L. Chavez, A. Margol, M. Pekmezci, Chan Chung, Adam Banda, J. Bayliss, S. Curry, M. Santi, F. Rodriguez, M. Snuderl, M. Karajannis, A. Saratsis, C. Horbinski, A. Carret, B. Wilson, D. Johnston, L. Lafay-Cousin, S. Zelcer, D. Eisenstat, Marianna Silva, Katrin Scheinemann, N. Jabado, P. Mcneely, M. Kool, S. Pfister, Michael D. Taylor, C. Hawkins, A. Korshunov, A. Judkins, S. Venneti   +39 more
semanticscholar   +1 more source

Clinical evidence of variable proton biological effectiveness in pediatric patients treated for ependymoma

Radiotherapy and Oncology, 2016
Background and Purpose A constant relative biological effectiveness (RBE) is used for clinical proton therapy; however, experimental evidence indicates that RBE can vary.
C. Peeler, D. Mirkovic, U. Titt, P. Blanchard, J. Gunther, A. Mahajan, R. Mohan, D. Grosshans   +7 more
semanticscholar   +1 more source

Sacral myxopapillary ependymoma with extensive osteolysis

, 2006
Myxopapillary ependymoma rarely presents as a primary intra-sacral lesion and extensive bony destruction is unusual. Radiological features do not help in distinction from other commoner sacral tumors, like chordoma.
Gupta, Ruchika, Sarkar, Chitra, Rishi, Arvind, Sharma, Meher C., Gupta, Aditya, Suri, Vaishali, Garg, Ajay   +6 more
core   +1 more source

A De Novo Mouse Model of C11orf95-RELA Fusion-Driven Ependymoma Identifies Driver Functions in Addition to NF-κB

Cell Reports, 2018
Summary: The majority of supratentorial ependymomas (ST-ependymomas) have few mutations but frequently display chromothripsis of chromosome 11q that generates a fusion between C11orf95 and RELA (RELAFUS). Neural stem cells transduced with RELAFUS ex vivo
Tatsuya Ozawa, Sonali Arora, Frank Szulzewsky, Gordana Juric-Sekhar, Yoshiteru Miyajima, Hamid Bolouri, Yoshie Yasui, Jason Barber, Robert Kupp, James Dalton, Terreia S. Jones, Mitsutoshi Nakada, Toshihiro Kumabe, David W. Ellison, Richard J. Gilbertson, Eric C. Holland   +15 more
doaj   +1 more source

Heterogeneity within the PF-EPN-B Ependymoma Subgroup

Acta Neuropathologica, 2018
Posterior fossa ependymoma comprise three distinct molecular variants, termed PF-EPN-A (PFA), PF-EPN-B (PFB), and PF-EPN-SE (subependymoma). Clinically, they are very disparate and PFB tumors are currently being considered for a trial of radiation ...
F. Cavalli, Jens-Martin Hübner, Tanvi Sharma, B. Luu, M. Sill, M. Zápotocký, S. Mack, H. Witt, Tong Lin, D. Shih, Ben Ho, M. Santi, Lyndsey Emery, J. Hukin, C. Dunham, R. McLendon, E. Lipp, S. Gururangan, Andrew Grossbach, P. French, J. Kros, M. van Veelen, A. N. Rao, C. Giannini, S. Leary, Shin Jung, C. Faria, J. Mora, U. Schüller, M. Alonso, J. Chan, Á. Klekner, L. Chambless, E. Hwang, M. Massimino, C. Eberhart, M. Karajannis, B. Lu, L. Liau, M. Zollo, Veronica Ferrucci, C. Carlotti, D. Tirapelli, U. Tabori, E. Bouffet, M. Ryzhova, D. Ellison, T. Merchant, M. Gilbert, T. Armstrong, A. Korshunov, S. Pfister, Michael D. Taylor, K. Aldape, K. Pajtler, M. Kool, V. Ramaswamy   +56 more
semanticscholar   +1 more source

Intramedullary spinal cord ependymoma and astrocytoma: intraoperative frozen-section diagnosis, extent of resection, and outcomes.

Journal of Neurosurgery : Spine, 2019
OBJECTIVEThe intraoperative differentiation of ependymomas from astrocytomas is important because neurosurgical strategies differ between these two tumor groups.
Hiroki Hongo, K. Takai, T. Komori, M. Taniguchi   +3 more
semanticscholar   +1 more source

Extraneural Metastasis of Ependymoma in Children: A Clinical Case

Вопросы современной педиатрии, 2019
Background. Ependymomas are a group of glial tumours, usually occurring in the posterior cranial fossa, less often — in the lateral ventricles and spinal cord.
Liudmila V. Olkhova, Olga G. Zheludkova, Vladimir E. Popov, Alexey N. Kislyakov, Timur M. Basalay, Svetlana V. Gorbatyh, Dmitry A. Skobeev, Natalya I. Zelinskaya   +7 more
doaj   +1 more source

Newly Diagnosed Metastatic Intracranial Ependymoma in Children: Frequency, Molecular Characteristics, Treatment, and Outcome in the Prospective HIT Series.

The Oncologist, 2019
BACKGROUND Data on frequency, clinical presentation, and outcome of primary metastatic intracranial ependymoma in children are scarce. PATIENTS AND METHODS Prospective data on patients younger than 21 years with metastatic intracranial ependymoma at ...
M. Benesch, M. Mynarek, H. Witt, M. Warmuth-Metz, T. Pietsch, B. Bison, S. Pfister, K. Pajtler, M. Kool, U. Schüller, K. Pietschmann, B. Juhnke, S. Tippelt, G. Fleischhack, I. Schmid, C. Kramm, P. Vorwerk, A. Beilken, C. Classen, P. Hernáiz Driever, G. Kropshofer, T. Imschweiler, A. Lemmer, R. Kortmann, S. Rutkowski, K. von Hoff   +25 more
semanticscholar   +1 more source

Myxopapillary ependymoma with intracranial metastases.

, 2005
We report spontaneous seeding within the subarachnoid space from a myxopapillary ependymoma that progressed despite surgery and radiotherapy ...
Summers, DM, Erridge, SC, Higgins, GS, Smith, C, Statham, PX   +4 more
core   +1 more source