Editing Out Seizures? Base Editing Shows Promise for SCN8A DEE. [PDF]
Riccio F, Lignani G.
europepmc +1 more source
DTI and SMIfw diffusion models applied in persons with multiple sclerosis revealed region‐specific sensitivity to microstructural injury, but performance differed by anatomical region. SMIfw neurite density fraction demonstrated high sensitivity and reliability in both the brain and spinal cord, whereas DTI measures such as fractional anisotropy and ...
Atlee Witt +8 more
wiley +1 more source
Specialized aldo-keto reductases trigger complete degradation of mycotoxin deoxynivalenol. [PDF]
He W +20 more
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Physical Anchoring‐Assisted Mechanically Guided Assembly for Material‐Independent 3D Mesostructures
Conventional mechanically guided 3D assembly relies on selective chemical bonding between 2D precursors and elastomeric substrates, imposing fundamental limitations on material compatibility and scalability. Here, we present a physically anchored, buckling‐guided assembly platform based on a rod array patterned elastomeric substrate (RPES).
Yeonhee Heo +7 more
wiley +1 more source
Stereoselective Cytotoxicity of Enantiopure 3,3-Dichloro-γ-lactams: Correlating In Vitro Activity with In Vivo Tolerability. [PDF]
Diaba F, Teixidó E, Morán MDC.
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Programmable Inter‐Droplet Communication by Polymer‐Gated Ion Transport Through Nanopore Lattices
Laser‐written polyelectrolyte barriers were applied for regulating imbibition and ion transport through silica mesopores between droplet compartments. Specific imbibition sequences and precipitation readouts indicated cation‐selective transport across the barriers. Depending on salt identity, barrier, and experimental parameters, ionic transport ranged
Marius Kirsch +4 more
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Inverse Design of Multi-Wavelength Achromatic Metalens Integrated On-Chip with Planar Waveguide. [PDF]
Podobrii M, Barulina E, Barulin A.
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Recent Advances in the Molecular Mechanisms of Bacterial Anti‐Phage Defence Systems
Panoptes as an example for an antiphage system consists of OptS producing a cyclic dinucleotide that prevents activation of OptE, a transmembrane protein. Phage T4 infection introduces the sponge protein Acb2 that adsorbs the cyclic dinucleotide thus activating OptE which disrupts the cell membrane aborting phage infection.
Harald Brüssow
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ABSTRACT Aims Empagliflozin is renoprotective in Type 2 diabetes mellitus (T2DM). Our primary aim was to assess empagliflozin's effect on glomerular filtration rate and renal vascular resistance using multiparametric MRI (MpMRI). Our secondary aim was to assess the impact of empagliflozin on additional MpMRI‐derived metrics including markers of tissue ...
Ruth P. Lim +9 more
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Impacts of Replacing Fish Meal With Duck By-Product Meal in Diets on Growth Performance, Feed Utilization, and Economic Efficiency of Olive Flounder (<i>Paralichthys olivaceus</i>). [PDF]
Shin SW, Cho SH.
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