Results 221 to 230 of about 856,627 (332)

Strong Implications From Small Deviations in Labeling Patterns: The Mechanism of Burkholderia gladioli Pacifigorgiadiene Synthase

Chemistry – A European Journal, EarlyView.
The mechanism of pacifigorgiadiene synthase from Burkholderia gladioli was investigated through isotopic labeling experiments and DFT calculations. The results revealed an unexpected labeling pattern which appeared to be different in the main and the side products, requiring unprecedented mechanistic explanations, including a “break‐flip‐cyclise ...
Zhiyong Yin, Zhehui Hu, Xiyuan He, Juan Xu, Bernd Goldfuss, Jeroen S. Dickschat, Guangkai Bian   +6 more
wiley   +1 more source

Low serum albumin levels and the nongerminal center B-cell subtype according to the Hans algorithm as strong prognostic factors in ≥ 80-year-old patients with large B-cell lymphoma treated with rituximab-containing chemotherapy. [PDF]

Ann Hematol
Kawashima I, Nakadate A, Hyuga H, Matsuura M, Sakamoto Y, Suzuki J, Kumagai T, Suzuki M, Yamanda-Koshiishi M, Yamamoto T, Nakajima K, Oishi N, Kondo T, Kirito K.   +13 more
europepmc   +1 more source

ADC measurements with EPI scans

, 2013
C Biagini
openalex   +1 more source

ASNOM mapping of SiC epi-layer doping profile and of surface phonon\n polariton waveguiding [PDF]

, 2013
D. V. Kazantsev
openalex   +1 more source

Isoform Specificity of a Compound Targeting Actin Filaments Containing Tropomyosin Tpm1.8/1.9

Cytoskeleton, EarlyView.
ABSTRACT The unbranched actin filaments in mammalian cells are usually composed of co‐polymers of a specific tropomyosin isoform with actin. Genetic manipulation has revealed that the tropomyosins largely define the functional properties of actin filaments in an isoform‐specific, non‐redundant manner.
Jeff Hook, Edna C. Hardeman, Peter W. Gunning   +2 more
wiley   +1 more source

Exocrine Pancreatic Insufficiency Manifesting Before Insulin Dependence in Adult-Onset Type 1 Diabetes. [PDF]

Clin Case Rep
Pavlou P, Pandit S, Karalliedde J.
europepmc   +1 more source

Synthesis of 20-Epi-eldecalcitol [20-Epi-1α,25-dihydroxy-2β-(3-hydroxypropoxy)vitamin D3: 20-Epi-ED-71]

, 2009
Noboru Kubodera, Madoka Yoshino, Kohei Eto, Keisuke Takahashi, Jun Ishihara, Susumi Hatakeyama, Yoshiyuki Ono, Hitoshi Saitô   +7 more
openalex   +1 more source

An IQ Consortium Perspective on the FDA Guidance for Assessment of Pharmacokinetics in Participants With Impaired Renal Function

Clinical Pharmacology &Therapeutics, EarlyView.
The FDA published guidance on assessing pharmacokinetics (PK) in participants with impaired renal function in 2024. The IQ CPLG Organ Impairment Working Group summarized the industry’s perspective on this guidance by highlighting a few key updates in the 2024 guidance, including: (1) the recommendation of using estimated glomerular filtration rate ...
Yan Jin, Ashish Sharma, Mariam A. Ahmed, Sravanthi Cheeti, Ying Ou, Damayanthi Devineni, Yizhe Chen, Jitendra S. Kanodia, Yasmeen Abouelhassan, Nadia Noormohamed, Jin Zhou, Patrick Marroum, Vaishali Sahasrabudhe, Islam R. Younis   +13 more
wiley   +1 more source

Test accuracy of glomerular filtration rate estimation with creatinine and cystatin C in adults with moderate chronic kidney disease: prospective cohort study. [PDF]

BMJ Med
Lamb EJ, Barratt J, Brettell EA, Cockwell P, Dalton RN, Deeks JJ, Eaglestone G, Kalra P, Khunti K, Loud FC, Mead PA, Ottridge R, Pellatt-Higgins T, Potter A, Rowe C, Scandrett K, Sharpe C, Shinkins B, Sitch AJ, Smith A, Stevens PE, Sutton AJ, Taal M.   +22 more
europepmc   +1 more source

Palladium(II)-catalyzed Stereocontrolled Cyclization via Hemiacetal Intermediates: Total Synthesis of 5-Epi-prelactone C

, 2004
Masahiro Miyazawa, Magsarjav Narantsetseg, Hajime Yokoyama, Seiji Yamaguchi, Yoshiro Hirai   +4 more
openalex   +1 more source