Molecular features of prenylated (iso)flavonoids from Fabaceae in relation to their potential NorA inhibition in <i>Staphylococcus aureus</i>. [PDF]
Irianti MI +4 more
europepmc +1 more source
Enzymatic Synthesis of Demethylated Sesquiterpenes From 14‐nor‐Farnesyl Pyrophosphate
The substrate analog 14‐nor‐FPP was synthesised and enzymatically converted with 10 bacterial and fungal sesquiterpene synthases, resulting in the isolation of 12 demethylated sesquiterpenes in yields up to 17%. In most cases the demethyl analogs of the FPP‐derived natural products were obtained, but also different products showing modified ...
Kizerbo A. Taizoumbe +1 more
wiley +1 more source
Juyoung Lee, Kyong Hwan Jin, J. C. Ye
semanticscholar +1 more source
Resolution of generalized tonic seizures following focal ablative or resective surgery
Abstract Objective Focal brain lesions may underlie generalized tonic seizures, as seen in Lennox–Gastaut syndrome, by engaging bilateral neural networks. However, this seizure type is often not considered surgically remediable. Here, we describe the resolution of apparent electroclinically classic generalized tonic seizures in children originating ...
Sem L. Kampman +3 more
wiley +1 more source
Combined Creatinine and Cystatin C Equations Improve Estimation of Glomerular Filtration Rate in Kidney Transplant Recipients. [PDF]
Mondésert E +5 more
europepmc +1 more source
Abstract Background People with epilepsy have diverse healthcare needs, but limited resources make tailored management challenging. To allocate resources where they are most urgently required, we developed an openly available needs‐based follow‐up model.
Isak Birkeland +10 more
wiley +1 more source
Evaluating the Efficacy of Polyphenol-Enriched Plant Extracts and Pathway Modulators in the Bone Marrow to Suppress Breast Cancer Progression. [PDF]
Javrushyan H +7 more
europepmc +1 more source
Abstract Objective Pathogenic variants in γ‐aminobutyric acid type A (GABAA) receptor genes have been associated with a wide spectrum of neurological disorders. We aimed to delineate the clinical trajectories associated with gain‐of‐function (GoF) and loss‐of‐function (LoF) variants in GABRB2 and GABRB3, and to develop a risk‐prediction model for gross
Sebastian Ortiz +73 more
wiley +1 more source
Ask not for whom the bell tolls: a meditation on the utility of serum creatinine on Critical Care. [PDF]
Roy RM +7 more
europepmc +1 more source
Did the French pregnancy pictogram change antiseizure medication use during pregnancy?
Abstract Objective The aim of this study was to assess the impact of introducing a pregnancy pictogram on medication packaging on the prescription and dispensation of antiseizure medications and on the maternal and neonatal outcomes for women exposed to these medications.
Mélanie Araujo +7 more
wiley +1 more source

