Results 71 to 80 of about 267,158 (314)

Extinction and recurrence of multi-group SEIR epidemic

, 2013
In this paper, we consider a class of multi-group SEIR epidemic models with stochastic perturbations. By the method of stochastic Lyapunov functions, we study their asymptotic behavior in terms of the intensity of the stochastic perturbations and the ...
Yang, Qingshan, Mao, Xuerong
core   +1 more source

UCHL3 Regulates Subgenomic Flaviviral RNA Condensates to Promote Virus Propagation

Advanced Science, EarlyView.
ABSTRACT Flavivirus subgenomic RNAs (sfRNAs) antagonise antiviral defences, yet how sfRNAs are organized and maintained in cells remains poorly understood. Here we identify ubiquitin C‐terminal hydrolase L3 (UCHL3) as a post‐translational regulator of flavivirus sfRNA stability and function.
Oscar Trejo‐Cerro, Anna Beekmayer‐Dhillon, Qi Wen Teo, Lewis Siu, Ming Yuan Li, Kate J. Heesom, Adán Pinto‐Fernández, Sumana Sanyal   +7 more
wiley   +1 more source

Eco‐Geography Reverses Dominant AMR Reservoirs in Klebsiella pneumoniae: Integron‐Rich Mobilomes and Cross‐Niche Connectivity

Advanced Science, EarlyView.
Dominant antimicrobial resistance reservoirs in Klebsiella pneumoniae vary across eco‐geographic settings rather than following a universal pattern. Integrated One Health and global genomic analyses show that lineage structure, integron load, and cross‐niche connectivity shape whether AMR burden accumulates primarily in human or nonhuman compartments ...
Hui Lin, Biao Tang, Hao Xu, Jiajie Qian, Feifan Shi, Junhui Zhao, Xiaorui Mao, Xiaohe Hu, Ruishan Liu, Wenhong Liu, Xiawei Jiang, Beiwen Zheng, Guoping Zhao   +12 more
wiley   +1 more source

Stochastic epidemic models: A survey [PDF]

Mathematical Biosciences, 2010
This paper is a survey paper on stochastic epidemic models. A simple stochastic epidemic model is defined and exact and asymptotic model properties (relying on a large community) are presented. The purpose of modelling is illustrated by studying effects of vaccination and also in terms of inference procedures for important parameters, such as the basic
openaire   +3 more sources

Lactoferrin Deficiency During Lactation Causes Adult Obesity‐Related Metabolic Disease Through Persistent Adipose Dysfunction Driven by Impaired Adipocyte Development

Advanced Science, EarlyView.
Lactational lactoferrin deficiency exerts lasting effects on epididymal adipose tissue development from lactation into adulthood: it impairs adipocyte hyperplasia and induces pathological hypertrophy, resulting in lower body weight yet exacerbated metabolic dysfunction under a high‐fat diet in adulthood.
Qin An, Yunxia Zou, Wenli Wang, Zhimei Cheng, Zhuoxing Zhang, Ruwei Liu, Xiong Wang, Kunlun Huang, Fangrong Ding, Yunping Dai, Qingyong Meng, Yali Zhang   +11 more
wiley   +1 more source

Conditions for a Second Wave of COVID-19 Due to Interactions Between Disease Dynamics and Social Processes

Frontiers in Physics, 2020
In May 2020, many jurisdictions around the world began lifting physical distancing restrictions against the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Sansao A. Pedro, Frank T. Ndjomatchoua, Peter Jentsch, Peter Jentsch, Jean M. Tchuenche, Madhur Anand, Chris T. Bauch   +6 more
doaj   +1 more source

Discrete-Time Household Epidemic Models

We present a general Markovian discrete-time SIR household epidemic model based on time units of a day. The model is flexible in how within-household infection depends upon the number of infectives at a given time and the interactions between global ...
Martin, Niamh, Sirl, David, Ball, Frank, Neal, Peter   +3 more
core   +1 more source

Is there the potential for an epidemic of variant Creutzfeldt-Jakob disease via blood transfusion in the UK?

, 2007
The discovery of three individuals suspected to have contracted variant Creutzfeldt-Jakob disease (vCJD) through blood transfusions has heightened concerns that a secondary epidemic via human-to-human transmission could occur in the UK. The Department of
Will, Robert G, Ghani, Azra C, Clarke, Paul   +2 more
core   +1 more source

A laminar flow model of aerosol survival of epidemic and non-epidemic strains of Pseudomonas aeruginosa isolated from people with cystic fibrosis [PDF]

, 2008
YesCystic fibrosis (CF) is an inherited multi-system disorder characterised by chronic airway infection with pathogens such as Pseudomonas aeruginosa. Acquisition of P.
Daniel G Peckham, Clifton Ian J, Denton, M, Peckham Daniel G, Fletcher, L.A., Peckham, DG, Beggs, CB, Fletcher, LA, Beggs, C.B., Denton Miles, Clive B Beggs, Fletcher Louise A, Clifton, I.J., Peckham, D.G., Beggs, Clive B., Denton, M., Miles Denton, Louise A Fletcher, Beggs Clive B, Ian J Clifton, Clifton, IJ   +20 more
core   +1 more source

Multi‐Stimuli‐Responsive Hydrogen‐Bonded Organic Frameworks Nanocarriers Enable Targeted Fungicide Release and Plant Immune Regulation

Advanced Science, EarlyView.
A fluorinated hydrogen‐bonded organic framework nanocarrier (PFC‐1‐F) loaded with PYR and coated with HACC enables multi‐stimuli‐responsive (enzyme/ROS/pH) release at infection sites. Exhibiting targeted antifungal activity against Sclerotium rolfsii, modulating plant antioxidant defense, and demonstrating favorable biosafety across plant, soil, and ...
Guangming Ma, Ying Zou, Yao Wang, Huiyan Li, Jinlin Li, Tianfu Liu, Xiaohong Pan   +6 more
wiley   +1 more source