Results 111 to 120 of about 209,474 (310)
ProTides for Antiviral Activity Beyond Liver Cells
Chemistry – A European Journal, EarlyView.A strategy for obtaining prodrugs of antiviral nucleotides with broad tissue activity is presented that relies on cycloalkyl or cycloalkylalkyl esters, improving uptake and esterase cleavage, and producing nanomolar inhibitors in kidney, colon, and lung cells.
Felix Goebel +5 more
wiley +1 more source
Эпидемиология и вакцинопрофилактикаRelevance. In the modern period, there are more and more publications showing that the COVID-19 pandemic has significantly affected the epidemiological situation with regard to a wide variety of infections, and having a different transmission mechanism ...
A. A. Yakovlev +3 more
doaj +1 more source
Bayesian inverse ensemble forecasting for COVID‐19
Canadian Journal of Statistics, EarlyView.Abstract Variations in strains of COVID‐19 have a significant impact on the rate of surges and on the accuracy of forecasts of the epidemic dynamics. The primary goal for this article is to quantify the effects of varying strains of COVID‐19 on ensemble forecasts of individual “surges.” By modelling the disease dynamics with an SIR model, we solve the ...
Kimberly Kroetch, Don Estep
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.As antiretroviral therapy (ART) prolongs lifespans, people with HIV (PWH) face a new syndemic: Cardiovascular‐Kidney‐Metabolic (CKM) syndrome. Yet CKM in PWH is poorly characterized. Inflammation, complex pharmacokinetic (PK) alterations, ART‐associated metabolic effects, and gut dysbiosis amplify risk. Managing CKM increases medication burden, thereby
Aaron S. Devanathan, Thomas D. Nolin
wiley +1 more source
Epidemic Process of Salmonellosis in Tashkent
Indian Journal of Forensic Medicine & Toxicology, 2020 In the latest decade, epidemiological features of salmonellosis morbidity have changed, in particular, thefraction of humans and animals, caused by S. enteritidis, has increased. It was caused by social changesin the population life: widespread development of private property, increased population migration, rapiddevelopment of the public catering ...
openaire +2 more sources
Role of Subgraphs in Epidemics over Finite-Size Networks under the Scaled SIS Process [PDF]
, 2014 Jun Zhang, José M. F. Moura
openalex +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.The global HIV response aims for widespread availability of affordable, quality‐assured long‐acting antiretroviral (LA ARV) drugs to achieve sustained epidemic control, particularly in low‐ and middle‐income countries. This report summarizes key discussion points, findings, and outcomes from an international workshop on generic LA ARVs, held in ...
Usman Arshad +22 more
wiley +1 more source
A sub-exponential branching process to study early epidemic dynamics with application to Ebola [PDF]
, 2019 Alexander E. Zarebski +2 more
openalex +1 more source
A Wiener process with jumps to model the logarithm of new epidemic cases
, 2022 Mario Lefebvre
openalex +1 more source