Results 91 to 100 of about 865,518 (384)

An open challenge to advance probabilistic forecasting for dengue epidemics

Proceedings of the National Academy of Sciences of the United States of America, 2019
Significance Forecasts routinely provide critical information for dangerous weather events but not yet for epidemics. Researchers develop computational models that can be used for infectious disease forecasting, but forecasts have not been broadly ...
M. Johansson, K. Apfeldorf, Scott Dobson, J. Devita, A. Buczak, Benjamin D. Baugher, L. Moniz, Thomas Bagley, S. Babin, Erhan Guven, T. Yamana, J. Shaman, Terry Moschou, Nick Lothian, Aaron Lane, Grant Osborne, Gao Jiang, L. Brooks, David C. Farrow, S. Hyun, R. Tibshirani, Roni Rosenfeld, J. Lessler, N. Reich, D. Cummings, S. Lauer, S. Moore, H. Clapham, R. Lowe, T. Bailey, M. García-Díez, M. Carvalho, X. Rodó, Tridip Sardar, R. Paul, E. Ray, K. Sakrejda, Alexandria C. Brown, Xi Meng, Osonde A. Osoba, R. Vardavas, D. Manheim, M. Moore, D. Rao, T. Porco, S. Ackley, Fengchen Liu, L. Worden, M. Convertino, Yang Liu, Abraham Reddy, E. Ortíz, J. Rivero, Humberto Brito, Alicia Juarrero, L. Johnson, R. Gramacy, Jeremy M. Cohen, E. Mordecai, C. Murdock, Jason Rohr, S. Ryan, Anna M. Stewart-Ibarra, Daniel P. Weikel, A. Jutla, Rakibul Khan, M. Poultney, R. Colwell, Brenda Rivera-García, C. Barker, J. Bell, M. Biggerstaff, D. Swerdlow, Luis Mier-y-Teran-Romero, B. Forshey, J. Trtanj, J. Asher, M. Clay, H. Margolis, Andrew M. Hebbeler, Dylan B. George, J. Chretien   +81 more
semanticscholar   +1 more source

Preventing Dengue Epidemics during the COVID-19 Pandemic

American Journal of Tropical Medicine and Hygiene, 2020
Preventing Dengue Epidemics during the COVID-19 Pandemic.
A. Wilder-Smith, H. Tissera, E. Ooi, J. Coloma, T. Scott, D. Gubler   +5 more
semanticscholar   +1 more source

Hyperviscous Diabetic Bone Marrow Niche Impairs BMSCs Osteogenesis via TRPV2‐Mediated Cytoskeletal‐Nuclear Mechanotransduction

Advanced Science, EarlyView.
Diabetic bone marrow exhibits pathological ECM hyperviscosity that activates TRPV2‐mediated Ca2⁺ influx, leading to perinuclear F‐actin disassembly, nuclear deformation, and chromatin condensation. This cytoskeletal‐nuclear decoupling suppresses osteogenic differentiation of BMSCs.
Yao Wen, Xinhui Zheng, Jieliu Li, Minyu He, Dongqi Fan, Xingyu Zhu, Qiming Zhai, Liangjing Xin, Tao Chen   +8 more
wiley   +1 more source

Addressing COVID-19 Communication and Management by a Systems Thinking Approach

Frontiers in Communication, 2020
A systemic stock-flow diagram is proposed for the communication and management of health services and strategies concerning the COVID-19 epidemic. The possible role of government interventions in activating systemic leverage points is also addressed. The
Francesco Gonella, Francesco Gonella, Marco Casazza, Silvio Cristiano, Alessandra Romano, Alessandra Romano   +5 more
doaj   +1 more source

Precision Editing of NLRS Improves Effector Recognition for Enhanced Disease Resistance

Advanced Science, EarlyView.
Precision engineering of plant NLR immune receptors enables rational design of enhanced pathogen resistance through mismatched pairing, domain swapping, and targeted mutagenesis. These approaches achieve multi‐fold expansion in recognition breadth while minimizing autoimmunity risks and fitness penalties.
Vinit Kumar, Vishwa I. P. W. A. Kumara, Pradeepa C. G. Bandaranayake, Dong Yawen, Yang‐Yang Gao, Junfeng Liu, Ge‐Fei Hao, Xiu‐Fang Xin   +7 more
wiley   +1 more source

Sources of Mapping used in Humanitarian Emergencies: The Case of Ebola

Quaestiones Geographicae, 2022
The need to rapidly respond to health emergencies has generated various institutional initiatives to identify their location, through mapping. This study employs a qualitative-exploratory method, based on the daily monitoring of eight Ebola epidemics ...
Barra Martínez José Antonio, Morales-Yago Francisco José, de Lázaro-Torres María Luisa   +2 more
doaj   +1 more source

AIEgen‐Based Proactive Early Warning System and Precise Treatment Strategy for Monkeypox Prevention and Control

Advanced Science, EarlyView.
An intelligent early warning and treatment system for monkeypox, utilizing a sprayable AIEgen‐ liquid dressing (AIE@LD) that responds to lesion pH. Integrated with a smartphone app and cloud platform, it enables real‐time infection detection via fluorescence imaging and triggers on‐demand photodynamic therapy under white light, effectively eradicating ...
Wei Wang, Zining Liu, Mengjun Li, Judun Zheng, Ruilin Zhang, Ke Liu, Xiaoxue Li, Shaoying Wen, Jingze Yu, Meijia Pan, Fengbo Ma, Kun Zhou, Zheng Zhao, Chenguang Shen, Yuhui Liao   +14 more
wiley   +1 more source

Stakeholders’ perspective on inclusion of key populations unique identifier codes in routine health information management system in South Africa

Southern African Journal of HIV Medicine
Background: The global community has set an ambitious goal of ending HIV as a public health risk by 2030. To achieve this, South Africa must have a robust routine health information management information system (RHIMS) that provides programmatic data ...
Mashudu Rampilo, Edith Phalane, Refilwe N. Phaswana-Mafuya   +2 more
doaj   +1 more source

Genome‐Wide Codon Reprogramming Enables a Multifactorially Attenuated Influenza Vaccine with Broad Cross‐Protection

Advanced Science, EarlyView.
Genome‐wide codon reprogramming of influenza A virus introduces 1956 synonymous mutations across five segments and elevates CpG content, causing defective NA packaging, loss of NS1 accumulation, and enhanced ZAP‐mediated antiviral responses without affecting RNA or protein synthesis. These mechanisms result in profound attenuation and potent homologous
Yang Wang, Tianxin Ma, Yujiao He, Qinming Li, Kailin Mai, Minying Mo, Chenyang Cao, Jiahui Li, Pei Feng, Jiaojiao Peng, Jing Sun, Weiqi Pan, Zifeng Yang, Ling Chen   +13 more
wiley   +1 more source

NAFLD‐related hepatocellular carcinoma: The growing challenge

Hepatology, EarlyView., 2022
Risk and protective factors for NAFLD‐related hepatocellular carcinoma Abstract Hepatocellular carcinoma (HCC) is a common cause of cancer‐related mortality and morbidity worldwide. With the obesity pandemic, NAFLD‐related HCC is contributing to the burden of disease exponentially.
Pir Ahmad Shah, Rashmee Patil, Stephen A. Harrison   +2 more
wiley   +1 more source