Results 171 to 180 of about 523,885 (310)

4‐Hydroxybenzyl Alcohol Mitigates Hyperlipidemia‐Associated Depression by Inhibiting Neuroinflammation via the NKIRAS2/NF‐κB Pathway

Advanced Science, EarlyView.
4‐HBA upregulates NKIRAS2 levels, inhibiting the activation of the NF‐κB pathway and subsequently reducing the levels of neuroinflammatory markers. This modulation helps restore normal mood and behavior in hyperlipidemic conditions, providing a potential therapeutic strategy for managing hyperlipidemia‐associated depression.
Ying Zhang, Meng Teng, Wenxuan He, Lanzhou Li, Yongfeng Zhang, Shimiao Wang, Chunyue Wang, Di Wang   +7 more
wiley   +1 more source

Health Effects Associated With Jet Fuel Exposure: Methods for a Fit-for-Purpose Systematic Review and Systematic Evidence Map. [PDF]

J Occup Environ Med
Bergeron JG, Cameron RL, Goodman SJ, Sprowles JLN, Snow SJ, Eftim SE, Haver CE, Vincent-Hall TD.   +7 more
europepmc   +1 more source

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

Understanding the Neurologic and Cognitive and Behavioral Effects Associated With Exposures to Jet Fuels: A Fit-for-Purpose Systematic Literature Review. [PDF]

J Occup Environ Med
Sprowles JLN, Allen BD, Lindahl AJ, Prince LM, Bowers EC, Martin EM, Kolanowski A, Lundin M, Goodman SJ, Starnes HM, Gillera SEA, Snow SJ, Eftim SE, Haver CE, Robertson M, Vincent-Hall TD.   +15 more
europepmc   +1 more source

A NeuroD1 AAV‐Based Gene Therapy for Functional Brain Repair in Alzheimer's Disease‐Like Non‐Human Primate Model

Advanced Science, EarlyView.
This study tests NeuroD1 AAV‐based gene therapy in a non‐human primate Alzheimer's disease model. The therapy prevents neuronal damage, inhibits hippocampal atrophy, and reduces neuroinflammation. It also repairs vascular and blood‐brain barrier damage, restores cerebrospinal fluid biomarkers, enhances hippocampal glucose metabolism, and improves ...
Zhouquan Jiang, Yongpeng Qin, Bin Luo, Fan Bai, Jiangyue Liu, Long Ma, Shu He, Rongjie Chen, Yuchen Wang, Shanggong Liu, Ying Sun, Yi Chen, Shuo Zhang, Jiaqi Liang, Feng Liao, Huiyi Wei, Junjie Wei, Lu Wang, Hao Xu, Zheng Wu, Gong Chen, Wenliang Lei   +21 more
wiley   +1 more source

Potential Health Impacts of Jet Fuel Exposure on the Hematologic and Cardiovascular Systems. [PDF]

J Occup Environ Med
Ross AM, Vidal J, Freedman AN, Kolanowski A, Miller SL, Goodman SJ, Sprowles JLN, Lindahl AJ, Snow SJ, Eftim SE, Haver CE, Vincent-Hall TD.   +11 more
europepmc   +1 more source

International Epidemiology [PDF]

International Journal of Epidemiology, 1981
openaire   +2 more sources

Synchrotron XRF Imaging Reveals Manganese Accumulation in the Golgi and Post‐Synapses of Neurons and Enhanced Uptake in Astrocytes

Advanced Science, EarlyView.
Despite widespread exposure, the mechanisms of manganese neurotoxicity remain poorly understood. Using correlative cryogenic fluorescence and synchrotron X‐ray fluorescence imaging techniques, we show that the Golgi apparatus is the primary accumulation site for manganese in both neurons and astrocytes, and that manganese targets the neuronal ...
Ines Kelkoul, Aiyarin Kittilukkana, Luis C. C. Huarte, Hiram Castillo‐Michel, Murielle Salome, Stéphane Roudeau, Pauline Belzanne, Matthieu Sainlos, Noémie Pied, Monica Fernandez‐Monreal, Daniel Choquet, Richard Ortega, Asuncion Carmona   +12 more
wiley   +1 more source

Assessing the Carcinogenic Potential of Jet Fuels: A Fit-for-Purpose Systematic Literature Review. [PDF]

J Occup Environ Med
Heitz ER, Allen BD, Goodman SJ, Freedman AN, Miller SL, Snow SJ, Eftim SE, Haver CE, Weinberger KR, Bergeron JG, Vincent-Hall TD.   +10 more
europepmc   +1 more source

Analysis of the Global Burden of Disease study highlights the global, regional, and national trends of chronic kidney disease epidemiology from 1990 to 2016 [PDF]

, 2018
Al-Aly, Ziyad, Bowe, Benjamin, Floyd, Tasheia, Li, Tingting, Maddukuri, Geetha, Mokdad, Ali H, Tsai, Cheng-You, Xian, Hong, Xie, Yan, Yan, Yan   +9 more
core   +1 more source