Results 181 to 190 of about 205,094 (258)

Oral Recombinant Human Collagen III Protects Gastric Mucosa via G‐Quadruplex‐Mediated Activation of the Pla2g4a‐Prostaglandin Axis

open access: yesAdvanced Science, EarlyView.
Orally administered recombinant human type III collagen protects the gastric mucosa from ethanol‐induced injury by coordinating redox homeostasis, epithelial barrier repair, and arachidonic acid–prostaglandin metabolism. Gastric digestion releases the pentapeptide GPAEF, which interacts with the Pla2g4a promoter G‐quadruplex in a structure‐dependent ...
Xinyue Lan   +14 more
wiley   +1 more source

Gut Microbial Topology and Metabolic Signatures Associated With Colorectal Neoplasia

open access: yesAdvanced Science, EarlyView.
The gut microbiota organizes into two robust association patterns linked to colorectal neoplasia risk. Topological shifts in microbial networks are associated with metabolite alterations and may shape host responses during disease development. ABSTRACT Alterations of gut microbial communities impact health.
Kai Song   +13 more
wiley   +1 more source

Neonatal Sevoflurane Exposure Induces Long‐Term Cognitive Impairment via Epigenetically Mediated MMP9 Activation and Perineuronal Net Disruption in the Hippocampal CA2

open access: yesAdvanced Science, EarlyView.
Hippocampal CA2 perineuronal nets ensheathing excitatory pyramidal neurons are selectively vulnerable to repeated neonatal sevoflurane exposure. Epigenetic upregulation of MMP9 via reduced H3K27me3 disrupts PNN integrity, impairs BDNF–TrkB signaling, and causes synaptic protein loss and dendritic spine deficits, leading to persistent social and spatial
Lirong Liang   +11 more
wiley   +1 more source

Advancing systems thinking in implementation science: An epidemiologic perspective. [PDF]

open access: yesAnn Epidemiol
Giovenco D   +7 more
europepmc   +1 more source

A Critique on the Methods and Scope of Epidemiology

open access: yesAmerican Journal of Public Health and the Nations Health, 1963
openaire   +3 more sources

[Epidemiology as a science and epidemiologic methods of knowledge].

open access: yesZhurnal mikrobiologii, epidemiologii i immunobiologii, 1982
K M, Siniak, O S, Davidenko
openaire   +1 more source

Epidemiologic, Entomologic, and Virologic Findings during Reemergence of Western Equine Encephalitis Virus, Argentina. [PDF]

open access: yesEmerg Infect Dis
Spinsanti L   +27 more
europepmc   +1 more source

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