Results 41 to 50 of about 2,291,030 (290)

Ecological co-burden patterns of GERD and asthma: a multi-method analysis of representative global regions

open access: yesFrontiers in Nutrition
BackgroundGastroesophageal reflux disease (GERD) and asthma often co-occur, yet their joint trajectories and shared drivers may differ across regions.MethodsUsing Global Burden of Disease (GBD) 2023 estimates (1994–2023), we compared East Asia, Tropical ...
Yinghan Deng   +4 more
doaj   +1 more source

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

open access: yesMolecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis   +20 more
wiley   +1 more source

Transition in Health Status in the Islamic Republic of Iran

open access: yesمجله اپیدمیولوژی ایران, 2006
Background and objectives: Data on transitions in health status are among the most important types of information used for promotion of health and social development.
M Naghavi
doaj  

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

open access: yesMolecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi   +2 more
wiley   +1 more source

Evaluating the stage of epidemiologic transition in Tunis, Tunisia [PDF]

open access: yes
With the rapid onset of globalization, there are a large number of political, economic and social factors which are constantly changing. These all have profound effects on the demographics of individual populations.
Sanders, David
core   +2 more sources

Infectious Disease Mortality Rates, Thailand, 1958–2009

open access: yesEmerging Infectious Diseases, 2012
To better define infectious diseases of concern in Thailand, trends in the mortality rate during 1958–2009 were analyzed by using data from public health statistics reports.
Suchunya Aungkulanon   +4 more
doaj   +1 more source

Economic growth, longevity and the epidemiological transition [PDF]

open access: yesThe European Journal of Health Economics, formerly: HEPAC, 2004
This paper integrates investments in health to a standard growth model where physical and human capital investments are the combined engines of growth. It shows the existence of two distinct health regimes separated by an "epidemiological transition." The various patterns of this transition identified in the epidemiological literature can be mapped ...
openaire   +3 more sources

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

The Burden of Cardiovascular Disease from Air Pollution in Rwanda

open access: yesAnnals of Global Health
Background: Rwanda, like many countries in sub-Saharan Africa, is still relatively early in development. Industrialization and urbanization are major drivers of the county’s economic growth. Rwanda is also undergoing an epidemiological transition, from a
Gabriella Taghian   +4 more
doaj   +1 more source

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk   +10 more
wiley   +1 more source

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