Results 71 to 80 of about 22,766,329 (360)

A Bayesian inference framework to reconstruct transmission trees using epidemiological and genetic data [PDF]

, 2012
The accurate identification of the route of transmission taken by an infectious agent through a host population is critical to understanding its epidemiology and informing measures for its control. However, reconstruction of transmission routes during an
King, D.P., Soubeyrand, S., Daniel T Haydon, Marco J. Morelli (118948), Donald P. King, Morelli, Marco J., Thébaud, G., Soubeyrand, Samuel, Thébaud, Gael, Marco J. Morelli, Joël Chadœuf, Chadœuf, J., Haydon, Daniel T., King Donald P., Soubeyrand Samuel, Morelli Marco J., Donald P King, Joël Chadœuf (118955), Daniel T. Haydon, Morelli, M.J., Thébaud Gaël, Chadoeuf, Joel, Haydon, D.T., Samuel Soubeyrand (118964), Morelli , Marco J., Marco J Morelli, Donald P. King (116717), Gaël Thébaud (118951), Chadœuf Joël, King, Donald P., Daniel T. Haydon (118960), Gaël Thébaud, Haydon Daniel T., Samuel Soubeyrand   +33 more
core   +1 more source

cano-wgMLST_BacCompare: A Bacterial Genome Analysis Platform for Epidemiological Investigation and Comparative Genomic Analysis

Frontiers in Microbiology, 2019
With the decreasing cost of next-generation sequencing, whole-genome sequence-based bacterial genome comparisons are expected to become a mainstream process in the public health domain.
Yen-Yi Liu, Ji-Wei Lin, Chih-Chieh Chen
semanticscholar   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Epidemiological investigation of esophageal carcinoma

World Journal of Gastroenterology, 2004
To review the characteristics of esophageal carcinoma in recent 30 years in the epidemiological investigation.A total of 1 520 cases of esophageal carcinoma in the First Affiliated Hospital of Zhejiang University Medical College admitted from 1970 until now were reviewed.
Hong, Zhang, Shao-Hua, Chen, You-Ming, Li   +2 more
openaire   +2 more sources

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Epidemiological methods in diarrhoea studies--an update. [PDF]

, 2011
BACKGROUND: Diarrhoea remains a leading cause of morbidity and mortality but is difficult to measure in epidemiological studies. Challenges include the diagnosis based on self-reported symptoms, the logistical burden of intensive surveillance and the ...
Barreto, Mauricio L, Bernd Genser, Clasen, Thomas, Wolf-Peter Schmidt, Thomas Clasen, Schmidt, Wolf-Peter, Sophie Boisson, Arnold, Benjamin F, Boisson, Sophie, Benjamin F Arnold, Luby, Stephen P, Genser, Bernd, Cairncross, Sandy, Mauricio L Barreto, Sandy Cairncross, Stephen P Luby   +15 more
core   +1 more source

Systemic cytokines and GlycA discriminate disease status and predict corticosteroid response in HTLV-1-associated neuroinflammation

Journal of Neuroinflammation, 2022
Background HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) is an incapacitating neuroinflammatory disorder for which no disease-modifying therapy is available, but corticosteroids provide some clinical benefit.
Tatiane Assone, Soraya Maria Menezes, Fernanda de Toledo Gonçalves, Victor Angelo Folgosi, Gabriela da Silva Prates, Tim Dierckx, Marcos Braz, Jerusa Smid, Michel E. Haziot, Rosa M. N. Marcusso, Flávia E. Dahy, Evelien Vanderlinden, Sandra Claes, Dominique Schols, Roberta Bruhn, Edward L. Murphy, Augusto César Penalva de Oliveira, Dirk Daelemans, Jurgen Vercauteren, Jorge Casseb, Johan Van Weyenbergh   +20 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Clinical and epidemiological investigation of a fatal anthrax case in China

Journal of Infection in Developing Countries, 2015
Anthrax is a recessive infectious disease caused by the bacterium Bacillus anthracis, and is primarily a zoonotic disease. Until recently, Bacillus anthracis infections were relatively infrequent and confined to agrarian communities in underdeveloped ...
Haiying Chen, Wanguo Bao, Yang Wang, Kaiyu Zhang, Feng Wang   +4 more
doaj   +1 more source

How are age-related differences in sleep quality associated with health outcomes? An epidemiological investigation in a UK cohort of 2406 adults

BMJ Open, 2017
Objectives To examine age-related differences in self-reported sleep quality and their associations with health outcomes across four domains: physical health, cognitive health, mental health and neural health.
Andrew Gadie, Meredith A. Shafto, Y. Leng, R. Kievit   +3 more
semanticscholar   +1 more source