Results 31 to 40 of about 693,120 (216)

Uncovering Inequities: The Role of Social Determinants of Health in Hospitalized Adolescents and Young Adults With Heavy Menstrual Bleeding

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Heavy menstrual bleeding (HMB) is a common condition among adolescents and young adults (AYAs) and is the leading cause of iron deficiency anemia (IDA) in this population. Growing evidence suggests that social determinants of health (SDOH) influence menstrual bleeding patterns, access to care, and treatment. However, no studies have
Maria Carter‐Febres, Cristina Tarango, Ashley Childress, Chunyan Liu, Evan Thomas, Jennifer Pomales, Eric S. Mullins   +6 more
wiley   +1 more source

Genetic risk score informed re-evaluation of phenotype quality control to maximize power in epidemiological studies: application to lung function

International Journal of Population Data Science
Introduction Clinical guidelines may reduce statistical power in epidemiological studies by discarding informative measures. Epidemiological studies of lung function may discard one-third to one-half of participants due to spirometry measures deemed ...
Jing Chen, Nick Shrine, Abril G Izquierdo, Anna Guyatt, Alex Williams, Henry Völzke, Stephanie London, Ian P Hall, Frank Dudbridge, SpiroMeta Consortium, CHARGE Consortium, Louise V Wain, Martin D Tobin, Catherine John   +13 more
doaj   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

Self-administered questionnaire assessing childhood cancer treatments and associated risks for adverse health outcomes - The KiKme study

Frontiers in Oncology, 2023
BackgroundChildhood cancer survivors (CCS) are at particularly high risk for therapy-related late sequelae, with secondary primary neoplasms (SPN) being the most detrimental.
Lara Kim Brackmann, Lara Kim Brackmann, Ronja Foraita, Heike Schwarz, Alicia Poplawski, Thomas Hankeln, Danuta Galetzka, Sebastian Zahnreich, Claudia Spix, Maria Blettner, Heinz Schmidberger, Manuela Marron   +11 more
doaj   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Predicting Mortality using Frailty Index and Latent Class Approaches: AUC-Based Evaluation in Simulated Data

Epidemiology, Biostatistics and Public Health
BACKGROUND The global population is aging rapidly, creating significant challenges for healthcare systems [1]. Traditional disease-centered models often fail to meet the complex needs of older adults, who frequently have multiple chronic conditions ...
Donato Martella , Antonella Zambon
doaj   +1 more source

Reporting on methods of subgroup analysis in clinical trials: a survey of four scientific journals

Brazilian Journal of Medical and Biological Research, 2001
Results of subgroup analysis (SA) reported in randomized clinical trials (RCT) cannot be adequately interpreted without information about the methods used in the study design and the data analysis.
E.D. Moreira Jr., Z. Stein, E. Susser
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Effectiveness of Laser Therapy in Adults with Knee Osteoarthritis: A Bivariate Meta-Analysis of Placebo-Controlled Randomized Controlled Trials

Epidemiology, Biostatistics and Public Health
Background: Knee pain represents the second most common musculoskeletal disorder after low back pain [1]. Knee osteoarthritis (OA) represents the leading cause of knee pain, as well as the most common site for OA, with a projected increase of 74.9 ...
Stefano Giuseppe Lazzarini, Donato Martella, Antonella Zambon   +2 more
doaj   +1 more source