Results 141 to 150 of about 379,138 (264)

Serious Infection in Crohn's Disease Patients Treated With Ustekinumab: US Food and Drug Administration Active Postmarket Risk Identification and Analysis in the Sentinel Initiative

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
The U.S. Food and Drug Administration (FDA) used an Active Postmarket Risk Identification and Analysis (ARIA) system to address a safety issue (serious infection) identified during clinical review of an application to market ustekinumab as a treatment for Crohn's disease (CD). FDA used an active‐comparator new‐user cohort design, data from six Sentinel
Joel L. Weissfeld   +9 more
wiley   +1 more source

Association of Neurodevelopmental Disorders and Congenital Anomalies With Prenatal Multiple Sclerosis Treatment—Real‐World Historical Cohort Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
There is a paucity of data regarding the effects of prenatal disease‐modifying therapies (DMTs) for multiple sclerosis (MS), on congenital anomalies in the offspring. Moreover, data on the association with neurodevelopmental disorders are lacking. This is an historical cohort study, within the Israeli Clalit Health Services database (2005–2024) that ...
Bar Rosh   +4 more
wiley   +1 more source

Development of Disordered Weight Control Behaviors and Its Progression to Eating Disorders in Canada: A Nationally Representative Microsimulation

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Eating disorders (ED) present a significant health burden to children, adolescents, and young adults globally. Despite the importance of disordered weight control behaviors (DWCB) in ED development, little is known about the progression from DWCB to ED.
Ye Shen   +5 more
wiley   +1 more source

Starving for Data: Eating Disorders Prevalence and Research Gaps in Southern Africa

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Studies reporting prevalence estimates of eating disorders in Southern Africa are scarce. To fill this gap, the present Research Forum reviews existing literature on the prevalence of eating disorders, including as assessed by clinical interviews, screeners, and self‐reported behaviors, among individuals in Southern Africa.
Bernou Melisse   +2 more
wiley   +1 more source

Eating Disorders in Boys and Men: A Gender‐Critical Narrative Review on Recognition, Stigma, and Treatment

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT In this narrative review, I highlight diversity‐related developments in eating disorder (ED) research, situate my own program of work on adult men within the broader literature on boys and men, and focus on risk factors, symptoms, diagnosis, and treatment in boys and men.
Georgios Paslakis
wiley   +1 more source

What happened after the epidemic? Equine influenza surveillance sheds light on sources and seasonal risk in the United Kingdom

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background The epidemiology of equine influenza (EI) in the United Kingdom has not been systematically described since the 2019 epidemic. Objectives To summarise UK EI surveillance (2020–2024), quantify outbreak seasonality and assess movement‐related sources. Study Design Retrospective observational analysis of national surveillance and horse
Fleur Whitlock   +2 more
wiley   +1 more source

Ischemic Stroke Burden in China and Other G20 Nations (1990–2021): A Comparative Analysis From the Global Burden of Disease Study 2021 and Trend Projections Through 2031

open access: yesHealth Care Science, EarlyView.
This study analyzes ischemic stroke (IS) burden in China and other G20 countries (1990–2021) using Global Burden of Disease 2021 data. China exhibited rising age‐standardized incidence rates (ASIR: +12.6%) and delayed mortality decline, contrasting with G20 reductions (ASIR: −9.3%; sustained ASMR fall).
Bin Luo   +4 more
wiley   +1 more source

Association of Chronic Diseases With Herpes Zoster in China: A Nationwide Population‐Based Survey

open access: yesHealth Care Science, EarlyView.
Chronic disease was associated with elevated herpes zoster risk (aOR = 1.84, 95% CI: 1.51–2.24). Among 14 chronic conditions, heart disease showed the strongest association (aOR = 2.91, 95% CI: 2.07–4.10), followed by diabetes (aOR = 2.04, 95% CI: 1.48–2.80) and hypertension (aOR = 1.89, 95% CI: 1.47–2.42).
Wenhui Zhu   +10 more
wiley   +1 more source

Prognostic Impact of Tumor Stage and Growth Pattern in Sinonasal Adenoid Cystic Carcinoma: A 15‐Year Population‐Based Study

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Sinonasal adenoid cystic carcinoma (AdCC) has a limited prognosis. This study assesses its incidence and prognostic factors in The Netherlands, focusing on histopathological features. Methods Adult patients diagnosed during 2008–2022 were retrieved through the Netherlands Cancer Registry and the Dutch Pathology Registry.
Lise J. van de Velde   +9 more
wiley   +1 more source

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