Results 71 to 80 of about 379,138 (264)

Genotypic and virulence characteristics of Listeria monocytogenes recovered from food items in Lebanon

Journal of Infection in Developing Countries, 2016
Introduction: Listeria monocytogenes is the agent of listeriosis, a life threatening foodborne disease for immunocompromised patients and pregnant women.
Nathaline Haidar-Ahmad, Kohar Annie B Kissoyan, Sukayna M Fadlallah, Rima El-Hajj, Majd Saleh, Nada Ghosn, Ghassan M Matar   +6 more
doaj   +1 more source

Modernising epidemic science: enabling patient-centred research during epidemics [PDF]

, 2016
Background: Emerging and epidemic infectious disease outbreaks are a significant public health problem and global health security threat. As an outbreak begins, epidemiological investigations and traditional public health responses are generally mounted ...
Horby, Peter W., Rojek, Amanda M.
core   +3 more sources

ACSL1‐Dependent Microglial Lipoimmunometabolic Reprogramming Underlies Cognitive Deficits in Alcohol Use Disorder

Advanced Science, EarlyView.
This study reveals that chronic alcohol exposure selectively upregulates ACSL1 expression in prefrontal cortical microglia, driving lipid metabolism reprogramming and lipid droplet accumulation, which activates the NLRP3 inflammasome and sustains neuroinflammation. To reverse this process, a dual‐targeted lipid nanoparticle, siACSL1@LNP‐MR, is designed
Liang Hao, Xing‐Rui Cao, Bai‐Qiang Li, Fu‐Ying Zhao, Jia‐Mei Wang, Rui‐Kang Gao, Zhi‐Peng Cao, Zhen‐Xian Du, Hua‐Qin Wang   +8 more
wiley   +1 more source

HEALTH RISK ASSESSMENT OF PESTICIDE EXPOSURE IN FARMERS AROUND RICE FARMING AREA IN OGAN ILIR REGENCY, SOUTH SUMATRA, INDONESIA

The Indonesian Journal of Public Health
Introduction: Pesticides are chemical compounds that are toxic to the environment and humans. Approximately 89.8% of farmers in South Sumatra use chemical pesticides.
Maksuk, Intan Kumalasari, Maliha Amin, Masdalina Pane   +3 more
doaj   +1 more source

Epidemiology of intensive care unit-acquired sepsis in Italy: results of the SPIN-UTI network [PDF]

, 2018
BACKGROUND: Sepsis is the major cause of mortality from any infectious disease worldwide. Sepsis may be the result of a healthcare associated infection (HAI): the most frequent adverse events during care delivery especially in Intensive Care Units ...
Agodi A, Arrigoni C, Auxilia F, Barchitta M, Brusaferro S, D'Errico MM, Fabiani L, Laurenti P, Mattaliano AR, Montagna MT, Mura I, Orsi GB, Pasquarella C, Squeri R, Tardivo S, Torregrossa MV   +15 more
core   +1 more source

A NeuroD1 AAV‐Based Gene Therapy for Functional Brain Repair in Alzheimer's Disease‐Like Non‐Human Primate Model

Advanced Science, EarlyView.
This study tests NeuroD1 AAV‐based gene therapy in a non‐human primate Alzheimer's disease model. The therapy prevents neuronal damage, inhibits hippocampal atrophy, and reduces neuroinflammation. It also repairs vascular and blood‐brain barrier damage, restores cerebrospinal fluid biomarkers, enhances hippocampal glucose metabolism, and improves ...
Zhouquan Jiang, Yongpeng Qin, Bin Luo, Fan Bai, Jiangyue Liu, Long Ma, Shu He, Rongjie Chen, Yuchen Wang, Shanggong Liu, Ying Sun, Yi Chen, Shuo Zhang, Jiaqi Liang, Feng Liao, Huiyi Wei, Junjie Wei, Lu Wang, Hao Xu, Zheng Wu, Gong Chen, Wenliang Lei   +21 more
wiley   +1 more source

Economic evaluation of the eradication program for bovine viral diarrhea in the Swiss dairy sector [PDF]

, 2017
The aim of this study was to conduct an economic evaluation of the BVD eradication program in the Swiss dairy sector. The situation before the start of the program (herd-level prevalence: 20%) served as a baseline scenario.
Häsler, B, Magouras, I, Meylan, M, Schüpbach-Regula, G, Thomann, B, Tschopp, A   +5 more
core   +2 more sources

Endometrial Epithelial Lactate Deficiency Drives CD8+ T‐Cells Dysregulation in Unexplained Recurrent Implantation Failure

Advanced Science, EarlyView.
Unexplained recurrent implantation failure (RIF) represents a significant clinical challenge. Our results demonstrate that reduced lactate production in the RIF endometrium impairs the suppression of cytotoxic CD8+ T‑cells, allowing their proliferation and thereby disrupting the local immune balance essential for successful embryo implantation.
Yuanlin He, Kang Ke, Qingxia Meng, Yichun Guan, Jichun Tan, Hong Lv, Boxian Huang, Chan Tian, Qinyan Zou, Mingxing An, Yao Gao, Jingjing Chen, Xiaoyu Wei, Xi Wang, Hongxia Ma, Yuan Lin, Feiyang Diao, Yayun Gu, Zhibin Hu   +18 more
wiley   +1 more source

Experience of field testing in Lebanon during the COVID-19 pandemic, January to August 2021

BMJ Global Health, 2022
Zeina Farah, Nada Ghosn, Tatiana Tohme, Hala Abou Naja, Reem Abdel Malak, Hawraa Sweidan, Hamad Hassan   +6 more
doaj   +1 more source

Antimicrobial stewardship programs in a Mexican private healthcare system: a self-assessment of core elements

BMC Infectious Diseases
Background Antimicrobial stewardship programs (ASPs) refer to a set of coordinated actions that improve the quality of care and combat antimicrobial resistance. Currently, information regarding the status of ASPs in Mexico is scarce. We aimed to describe
José Iván Castillo Bejarano, Dzoara Laura Lugo Ondarza, Juan O Galindo Galindo, Daniel Siller Rodríguez, Sara Paulina Rosales-González, Susana Patricia Cantú González, Jorge Alberto Vera Delgado   +6 more
doaj   +1 more source