Results 71 to 80 of about 212,235 (311)

An Integrative Strategy Delineates Modular Metabolic Remodeling and Potential Therapeutic Targets Across Metabolic Diseases

Advanced Science, EarlyView.
An integrative single‐cell atlas across multiple metabolic diseases reveals coordinated metabolic modules and disease‐shared versus disease‐specific pathway activities. By systematically comparing scoring strategies, a robust RankAve framework is established. Coupled with network analysis and drug‐target prediction, this resource uncovers cross‐disease
Kuan Yang, Congxue Hu, Hang Zhao, Xiao Peng, Yiming Yan, Jiasi Wang, Wenqi Jiang, Depeng Mu, Yan Cao, Xia Li, Yunpeng Zhang   +10 more
wiley   +1 more source

Review on the epidemiology and dynamics of BSE epidemics

, 2008
The paper describes how the comprehensive surveillance of bovine spongiform encephalopathy (BSE) and studies carried out on these data has enhanced our knowledge of the epidemiology of BSE.
Ducrot, C., Heim, D., Koeijer, A.A., de, Arnold, M., Calavas, D.   +4 more
core   +1 more source

Calcineurin‐Dependent Stress Adaptation Enables Caspofungin Heteroresistance Leading to Stable Resistance in Candida Glabrata

Advanced Science, EarlyView.
Caspofungin heteroresistance is prevalent in clinical Candida glabrata isolates and depends on calcineurin‐mediated stress adaptation. This transient phenotype serves as a reservoir for resistance evolution, enabling the emergence of stable resistant descendants under prolonged drug pressure.
Yanyu Su, Yi Li, Meng Xiao, Dan Guo, David S. Perlin, Erika Shor, Yingchun Xu, Yingxing Li   +7 more
wiley   +1 more source

Understanding Egg Price Volatility and Policy Implications in the U.S. With Machine Learning

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT Eggs are an inexpensive and sustainable source of proteins, but volatility in the U.S. egg prices has intensified in recent years, raising concerns over food affordability and market stability. This study examines the drivers of U.S. egg price dynamics over 2004–2025 using a two‐stage framework that combines LASSO‐based variable selection with
Xuemei Zhao, Simon Meister, Lucie Maruejols, Xiaohua Yu   +3 more
wiley   +1 more source

AI for epidemiological surveillance in animal health [PDF]

Since the early 2000s, several event-based surveillance (EBS) systems have been developed to collect information on epidemics published in online media (for example, ProMED-mail since 1994, HealthMap since 2006, PADI-web since 2016, EIOS since 2017 ...
Roche, Mathieu, Trevennec, Carlène
core  

Evaluation of surveillance methods for an epidemiological study of contact lens related microbial keratitis

, 2004
PURPOSE: To evaluate surveillance methods in a pilot epidemiological study of contact lens related microbial keratitis (MK) cases identified by ophthalmic practitioners in Australia and New Zealand between May and August 2003 inclusive.----- METHODS ...
Naduvilath, Thomas, Brian, Garry, Keay, Lisa, Stapleton, Fiona, Edwards, Katie P.   +4 more
core   +1 more source

Advances in Gastric Cancer Research: Insights Into Carcinogenesis, the Tumor Microenvironment, Metastasis, and Factors Influencing Prognosis

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background The Department of Gastroenterological Surgery at Kumamoto University has maintained a commitment to integrating cutting‐edge clinical practice with fundamental research, particularly concerning malignant diseases of the digestive tract.
Hideo Baba, Takatsugu Ishimoto, Yoshifumi Baba, Hiromitsu Hayashi, Masaaki Iwatsuki   +4 more
wiley   +1 more source

A diagnostics platform for the integrated mapping, monitoring, and surveillance of neglected tropical diseases: rationale and target product profiles. [PDF]

, 2012
A Diagnostics Platform for the Integrated Mapping, Monitoring, and Surveillance of Neglected Tropical Diseases: Rationale and Target Product ...
Xiao-Nong Zhou (92570), Chen, Jia Xu, Secor, W Evan, Robin L. Bailey (106607), Mabey, David C., Willingham, A Lee, Anthony W. Solomon (146301), Chen, Jun-Hu, Stothard, Russell; id_orcid, Peeling, Rosanna W., Stothard, J Russell, Xiao-Nong Zhou, Holland, Martin J., Bailey, Robin L., Blake, Isobel M, Wei, Hu, Chen, Jia-Xu, Isobel M. Blake (146313), Mohamed Rhajaoui, Nicholas C. Grassly (146341), Chen, Jun Hu, Lammie, Patrick J, Brooker, Simon, Willingham, A. Lee, A. Lee Willingham (84620), Jia-Xu Chen, Artemis Koukounari (35316), Alan Fenwick (35322), Edwards, Tansy, Artemis Koukounari, Tansy Edwards (122527), Michael French, Nicholas C Grassly, Solomon, Anthony W, Chris J. Drakeley (146329), Patrick J. Lammie (113203), Grassly, Nicholas C., Jun-Hu Chen, Koukounari, Artemis, A Lee Willingham, Drakeley, Chris J., Churcher, Thomas S., Harding-Esch, Emma M., Rhajaoui, Mohamed, Thomas S. Churcher (146323), Jun-Hu Chen (115591), Isobel M Blake, Anthony W Solomon, Gabrielli, Albis Francesco, Secor, W. Evan, Albis Francesco Gabrielli (146339), French, Michael, Hu Wei (146365), Albis Francesco Gabrielli, Hu Wei, W. Evan Secor (146357), J Russell Stothard, Zhou, Xiao Nong, Rosanna W. Peeling (146378), Zhou, Xiao-Nong, Jia-Xu Chen (115580), Jacqueline Leslie, Grassly, Nicholas C, Robin L Bailey, Martin J. Holland (146345), Holland, Martin J, David C Mabey, W Evan Secor, Blake, Isobel M., Fenwick, Alan, Chris J Drakeley, Drakeley, Chris J, Harding-Esch, Emma M, Peeling, Rosanna W, Emma M. Harding-Esch (146343), Martin J Holland, J. Russell Stothard (125710), Solomon, Anthony W., Dirk Engels, Alan Fenwick, Churcher, Thomas S, Patrick J Lammie, Michael French (146337), Engels, Dirk, Thomas S Churcher, Lammie, Patrick J., Emma M Harding-Esch, Jacqueline Leslie (146346), Simon Brooker (27005), David C. Mabey (146347), Tansy Edwards, Dirk Engels (39603), Bailey, Robin L, Simon Brooker, Mohamed Rhajaoui (146352), Leslie, Jacqueline, Mabey, David C, Rosanna W Peeling   +97 more
core   +1 more source

Effectiveness of the SARS-CoV-2 Vaccination in Preventing Severe Disease-Related Outcomes: A Population-Based Study in the Italian Province of Bolzano (South Tyrol)

International Journal of Public Health
Objective: To investigate the effectiveness of SARS-CoV2 vaccination in preventing ordinary or intensive care unit (ICU) admissions and deaths among cases registered during a variant transitional pandemic phase in the geographically and culturally unique
Antonio Lorenzon, Antonio Lorenzon, Lucia Palandri, Francesco Uguzzoni, Catalina Doina Cristofor, Filippo Lozza, Riccardo Poluzzi, Cristiana Rizzi, Pierpaolo Bertoli, Florian Zerzer, Elena Righi   +10 more
doaj   +1 more source

Liver diseases in Mexico and their associated mortality trends from 2000 to 2007: A retrospective study of the nation and the federal states

Annals of Hepatology, 2010
Introduction. Liver disease is a major health issue in Mexico. Although several studies have been performed to analyze the impact of liver diseases on the Mexican population, none has compared the prevalence and impact of liver disease between states ...
Nahum Méndez-Sánchez, Elsy García-Villegas, Beatriz Merino-Zeferino, Soledad Ochoa-Cruz, Antonio R. Villa, Herlinda Madrigal, Ramón A Kobashi-Margáin, Ylse Gutiérrez-Grobe, Norberto Chávez-Tapia, Guadalupe Ponciano-Rodríguez, Misael Uribe   +10 more
doaj   +1 more source