Study on resistance mechanisms and molecular epidemiology of carbapenem-resistant Pseudomonas aeruginosa to ceftazidime/avibactam in a certain region of China [PDF]
Xiaohui Qiao +7 more
openalex +1 more source
Prickle4 Drives Microenvironmental Remodeling and Resistance to Parp Inhibition in IDH‐Mutant Glioma
IDH‐mutant gliomas exhibit sensitivity to PARP inhibitors (PARPi) owing to oncometabolite 2‐HG‐induced DNA repair defects. PARPi treatment induces resistance by upregulating Prickle4, which promotes VEGF‐driven angiogenesis. Combining PARPi veliparib with anti‐angiogenic lenvatinib blocks this pathway, causing tumor regression and prolonged survival in
Ju Yang +16 more
wiley +1 more source
Epidemiology in health policies, programs, and services in Brazil: The trajectories and perspectives from ABRASCO's Fifth Strategic Plan for the Development of Epidemiology in Brazil (2025-2029). [PDF]
Magno L +8 more
europepmc +1 more source
This study unveils ITGA2⁺ tumor cells as key drivers of pediatric thyroid cancer aggressiveness. These cells orchestrate dual oncogenic pathways: GLUT1‐mediated glycolytic reprogramming and M2 macrophage polarization. This metabolic‐immunological crosstalk promotes tumor progression and metastasis.
Zhi‐jun Zhan +11 more
wiley +1 more source
Research in Epidemiology in Brazil: challenges, pathways, and commitments for the future. [PDF]
Boing AF +4 more
europepmc +1 more source
Different patterns of Toxoplasma gondii infection epidemiology in the general population, animal contact workers, and blood donors in southeastern China between 2019 and 2023: a cross-sectional study [PDF]
Xiaoxiao Wang +9 more
openalex +1 more source
NEAT1 Promotes Epileptogenesis in Tuberous Sclerosis Complex
The primary neurological manifestations of tuberous sclerosis complex (TSC) are intractable epilepsy and intellectual disability. NEAT1 is differentially expressed in TSC‐related epilepsy and influences neuronal excitability by regulating the PI3K/AKT/mTOR signaling pathway.
Suhui Kuang +8 more
wiley +1 more source
Establishing Goals, Techniques and Priorities for National Communicable Disease Surveillance
Anne Carter +1 more
doaj +1 more source

