Results 31 to 40 of about 1,303,488 (267)
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Statins, identified via the Comparative Toxicogenomics Database, promote monocytic differentiation and apoptosis in non‐APL AML cells by upregulating DPYSL2A through a KLF4‐dependent pathway. Mevalonate supplementation reversed these effects, indicating involvement of the mevalonate pathway.
Mina Noura +7 more
wiley +1 more source
The concept of meta-epidemiology has been introduced with considering the methodological limitations of systematic review for intervention trials. The paradigm of meta-epidemiology has shifted from a statistical method into a new methodology to close ...
Jong-Myon Bae
doaj +1 more source
Epidemiology of acute respiratory viral infections in children in Vientiane, Lao People's Democratic Republic [PDF]
Chantal J. Snoeck +10 more
openalex +1 more source
Colorectal cancer (CRC) mortality is highest in aged males. Pre‐clinical data comparing CRC i.p. metastasis in cohorts of young and aged, male and female mice support these finding. Bottom‐up proteomics of peritoneal mesothelial cells identified PTP4A1 as highly expressed in aged males and a role for PTP4A1 in heterotypic cell:cell adhesion was ...
Zhikun Wang +17 more
wiley +1 more source
Mortality from lung cancer and respiratory failure in US adults declined until 2010 but increased thereafter, with notable disparities by sex, race, region, and urbanicity. This 24‐year analysis highlights rising post‐2010 mortality in women, non‐Hispanic Whites, and urban areas, underscoring the need for targeted public health interventions.
Sardar M. I. Khan +10 more
wiley +1 more source
Epidemiology and biostatistics: fundamentals of research methodology
Epidemiology and statistics is an essential modern science whose understanding now forms a base of any research in any form. Epidemiology deals with the distribution and determinants of health-related states, while biostatistics is considered to be ...
Dhrubajyoti Bhuyan +2 more
doaj +1 more source
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath +3 more
wiley +1 more source
Preventive epidemiology as a branch of epidemiology [PDF]
Preventive epidemiology is a branch of epidemiology that differs from other branches in terms of focus, goals, and studying population. In other branches of epidemiology, the focus is on patients, while in preventive epidemiology, it is on healthy ...
Soleyman Alivand +3 more
doaj +1 more source
The recent upsurge in the number and magnitude of outbreaks of infectious diseases in Nigeria has been managed effectively and efficiently by the Nigeria Centre for Disease Control (NCDC) in an increasingly epidemiology guided approach led by a skilled ...
Patrick M. Nguku +3 more
doaj +1 more source

