Results 31 to 40 of about 1,303,488 (267)

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Statins induce monocytic differentiation in acute myeloid leukemia cells through the KLF4/DPYSL2A axis

open access: yesFEBS Open Bio, EarlyView.
Statins, identified via the Comparative Toxicogenomics Database, promote monocytic differentiation and apoptosis in non‐APL AML cells by upregulating DPYSL2A through a KLF4‐dependent pathway. Mevalonate supplementation reversed these effects, indicating involvement of the mevalonate pathway.
Mina Noura   +7 more
wiley   +1 more source

Meta-epidemiology [PDF]

open access: yesEpidemiology and Health, 2014
The concept of meta-epidemiology has been introduced with considering the methodological limitations of systematic review for intervention trials. The paradigm of meta-epidemiology has shifted from a statistical method into a new methodology to close ...
Jong-Myon Bae
doaj   +1 more source

Epidemiology of acute respiratory viral infections in children in Vientiane, Lao People's Democratic Republic [PDF]

open access: bronze, 2021
Chantal J. Snoeck   +10 more
openalex   +1 more source

Protein Tyrosine Phosphatase 4A1 (PTP4A1) Regulates Early Events in Colorectal Cancer Intraperitoneal Dissemination in the Aged Male Host

open access: yesAging and Cancer, EarlyView.
Colorectal cancer (CRC) mortality is highest in aged males. Pre‐clinical data comparing CRC i.p. metastasis in cohorts of young and aged, male and female mice support these finding. Bottom‐up proteomics of peritoneal mesothelial cells identified PTP4A1 as highly expressed in aged males and a role for PTP4A1 in heterotypic cell:cell adhesion was ...
Zhikun Wang   +17 more
wiley   +1 more source

Trends and Disparities in Lung Cancer and Respiratory Failure Mortality in the United States: A 24‐Year Retrospective Study

open access: yesAging and Cancer, EarlyView.
Mortality from lung cancer and respiratory failure in US adults declined until 2010 but increased thereafter, with notable disparities by sex, race, region, and urbanicity. This 24‐year analysis highlights rising post‐2010 mortality in women, non‐Hispanic Whites, and urban areas, underscoring the need for targeted public health interventions.
Sardar M. I. Khan   +10 more
wiley   +1 more source

Epidemiology and biostatistics: fundamentals of research methodology

open access: yesOpen Journal of Psychiatry and Allied Sciences, 2016
Epidemiology and statistics is an essential modern science whose understanding now forms a base of any research in any form. Epidemiology deals with the distribution and determinants of health-related states, while biostatistics is considered to be ...
Dhrubajyoti Bhuyan   +2 more
doaj   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

open access: yesAging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath   +3 more
wiley   +1 more source

Preventive epidemiology as a branch of epidemiology [PDF]

open access: yesJournal of Preventive Epidemiology
Preventive epidemiology is a branch of epidemiology that differs from other branches in terms of focus, goals, and studying population. In other branches of epidemiology, the focus is on patients, while in preventive epidemiology, it is on healthy ...
Soleyman Alivand   +3 more
doaj   +1 more source

Contributing to a Healthier Nigeria through Public Health Workforce Capacity Development: Afenet Experience in Nigeria

open access: yesThe Proceedings of the Nigerian Academy of Science, 2022
The recent upsurge in the number and magnitude of outbreaks of infectious diseases in Nigeria has been managed effectively and efficiently by the Nigeria Centre for Disease Control (NCDC) in an increasingly epidemiology guided approach led by a skilled ...
Patrick M. Nguku   +3 more
doaj   +1 more source

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