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The World Health Organization 2030 goals for Taenia solium: Insights and perspectives from transmission dynamics modelling [version 1; peer review: 2 approved]

open access: yesGates Open Research, 2019
Taenia solium (TS), responsible for porcine cysticercosis, human taeniasis and (neuro)cysticercosis, was included in the World Health Organization neglected tropical disease (NTD) roadmap published in 2012.
CystiTeam Group for Epidemiology and Modelling of Taenia solium Taeniasis/Cysticercosis
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

The World Health Organization 2030 goals for Taenia solium: Insights and perspectives from transmission dynamics modelling [version 2; peer review: 3 approved]

open access: yesGates Open Research, 2019
Taenia solium (TS), responsible for porcine cysticercosis, human taeniasis and (neuro)cysticercosis, was included in the World Health Organization neglected tropical disease (NTD) roadmap published in 2012.
CystiTeam Group for Epidemiology and Modelling of Taenia solium Taeniasis/Cysticercosis
doaj   +1 more source

EPI Update, October 9, 2009 [PDF]

open access: yes, 2009
Weekly newsletter for Center For Acute Disease Epidemiology of Iowa Department of Public ...

core  

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

Epidemiology of heart failure

open access: yesEuropean Journal of Heart Failure, 2020
The heart failure syndrome has first been described as an emerging epidemic about 25 years ago. Today, because of a growing and ageing population, the total number of heart failure patients still continues to rise.
A. Groenewegen   +3 more
semanticscholar   +1 more source

EPI Update, October 7 2005 [PDF]

open access: yes, 2005
Weekly newsletter for Center For Acute Disease Epidemiology of Iowa Department of Public ...

core  

GENETIC EPIDEMIOLOGY [PDF]

open access: yesAnnual Review of Genetics, 1993
Every science has roots that antedate acceptance as a discipline. Neglecting these intimations, there is a consensus that population genetics became a recognised science about 1920, and that it split into two branches about 1960. One branch is concerned with historical processes, uniting genetics with anthropology and (in other species) with ...
openaire   +3 more sources

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

open access: yesFEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer   +10 more
wiley   +1 more source

Meta-epidemiology [PDF]

open access: yesEpidemiology and Health, 2014
The concept of meta-epidemiology has been introduced with considering the methodological limitations of systematic review for intervention trials. The paradigm of meta-epidemiology has shifted from a statistical method into a new methodology to close ...
Jong-Myon Bae
doaj   +1 more source

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