Results 41 to 50 of about 2,651,054 (356)

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

Epidemiology and biostatistics: fundamentals of research methodology

open access: yesOpen Journal of Psychiatry and Allied Sciences, 2016
Epidemiology and statistics is an essential modern science whose understanding now forms a base of any research in any form. Epidemiology deals with the distribution and determinants of health-related states, while biostatistics is considered to be ...
Dhrubajyoti Bhuyan   +2 more
doaj   +1 more source

Meta-epidemiology [PDF]

open access: yesEpidemiology and Health, 2014
The concept of meta-epidemiology has been introduced with considering the methodological limitations of systematic review for intervention trials. The paradigm of meta-epidemiology has shifted from a statistical method into a new methodology to close ...
Jong-Myon Bae
doaj   +1 more source

EPI Update, October 9, 2009 [PDF]

open access: yes, 2009
Weekly newsletter for Center For Acute Disease Epidemiology of Iowa Department of Public ...

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How should public health professionals engage with lay epidemiology? [PDF]

open access: yes, 2006
"Lay epidemiology" is a term used to describe the processes through which health risks are understood and interpreted by laypeople. It is seen as a barrier to public health when the public disbelieves or fails to act on public health messages.
Allmark, P. J., Tod, A.
core   +2 more sources

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

open access: yesMolecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau   +9 more
wiley   +1 more source

Different Patterns of Association of Body Fat Percent and Body Mass Index with Pre-adolescent and Adolescent Asthma: a Cross-sectional Study Amongst Cypriot Schoolchildren [PDF]

open access: yes, 2012
IEA-EEF European Congress of Epidemiology, Porto, Portugal, September ...
Kolokotroni, K   +4 more
core   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

Contributing to a Healthier Nigeria through Public Health Workforce Capacity Development: Afenet Experience in Nigeria

open access: yesThe Proceedings of the Nigerian Academy of Science, 2022
The recent upsurge in the number and magnitude of outbreaks of infectious diseases in Nigeria has been managed effectively and efficiently by the Nigeria Centre for Disease Control (NCDC) in an increasingly epidemiology guided approach led by a skilled ...
Patrick M. Nguku   +3 more
doaj   +1 more source

EPI Update, April 14, 2006 [PDF]

open access: yes, 2006
Weekly newsletter for Center For Acute Disease Epidemiology of Iowa Department of Public ...

core  

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