Results 91 to 100 of about 2,098,761 (326)
Genome-Wide Association Study for Maize Leaf Cuticular Conductance Identifies Candidate Genes Involved in the Regulation of Cuticle Development. [PDF]
, 2020 The cuticle, a hydrophobic layer of cutin and waxes synthesized by plant epidermal cells, is the major barrier to water loss when stomata are closed at night and under water-limited conditions.
Baseggio, Matheus +12 more
core +2 more sources
Theranostics, 2019 Rationale: Cdc42 is a Rho GTPase that regulates diverse cellular functions. Here, we used genetic techniques to investigate the role of Cdc42 in epidermal development and epidermal barrier formation.
Min Zhang +13 more
semanticscholar +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Could Inflammaging and Its Sequelae Be Prevented or Mitigated? [PDF]
, 2019 Aged humans display a chronic and low-grade inflammation, termed "inflammaging", which has been potentially linked to the subsequent development of some aging-associated systemic disorders, including type 2 diabetes, atherosclerotic cardiovascular ...
Elias, Peter M, Man, Mao-Qiang
core
Epidermal Barrier Function Is Impaired in Langerhans Cell-Depleted Mice.
Journal of Investigative Dermatology, 2019 TO THE EDITOR Langerhans cells (LCs) are members of dendritic cell lineage located in the epidermis and are the outermost antigen-presenting cells to encounter pathogens at the skin surface (Merad et al., 2008). The functional role of LCs has been widely
Hae-jin Lee +7 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Emerging treatment options for the management of brain metastases in patients with HER2-positive metastatic breast cancer. [PDF]
, 2013 The widespread use of trastuzumab in the past decade has led to a significant and measureable improvement in the survival of patients with human epidermal growth factor receptor-2 (HER2) overexpressing breast cancer, and in many ways has redefined the ...
Chien, A Jo, Rugo, Hope S
core +1 more source
Asian Journal of Beauty and Cosmetology, 2016 표피의 각질형성세포가 세포분열과 분화를 거쳐 형성하는 각질층은 피부장벽의 핵심적인 조직이며 이러한 각질층의 형성과정에서 발생하는 불균형과 이상현상은 피부장벽의 기능 이상을 초래한다. 각질층의 기능을 조절하는 인자의 보다 상세한 이해를 위해, 본 논문은 피부장벽을 구성하는 각 요소를 자세히 서술해보았다. “Brick & Mortar” 모델에 따르면, 층판소체, 각질세포막, 지질, 칼슘, 사이토카인, 보습인자 등과 같은 피부장벽의 주된 요소가 자세히 묘사되어 있다. 각질층의 구조와 기능을 설명하는 가장 대표적인 모델은 “Brick & Mortar”로 설명되는 양분 모델이다.
Hyun Hee Jang, Sung Nae Lee
openaire +1 more source
The role of barrier genes in epidermal malignancy [PDF]
Oncogene, 2016 The outermost layer of the mammalian skin, the epidermis, forms a protective barrier against pathogenic microbes and tissue dehydration. This barrier is formed and maintained by complex genetic networks that connect cellular differentiation processes, enzymatic activities and cellular junctions.
C, Darido, S R, Georgy, S M, Jane
openaire +2 more sources
Arthritis Care &Research, EarlyView.Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo +88 more
wiley +1 more source