Results 111 to 120 of about 2,098,761 (326)
Transcriptional Regulation of Epidermal Barrier Formation [PDF]
, 2011 The mammalian epidermis is a self-renewing stratified squamous epithelium. Its basal cell layer contains proliferating keratinocytes that exit the cell cycle when they move into the suprabasal compartment. These cells activate a gene differentiation program aimed at building a protective epidermal barrier as they move toward the surface, successively ...
Ambica, Bhandari +3 more
openaire +2 more sources
Strategies for Loading and Releasing Peptide Therapeutics in Biodegradable Carriers
Advanced Functional Materials, EarlyView.A biodegradable carrier‐based peptide delivery system is a powerful treatment platform for diverse diseases, owing to its superior therapeutic efficacy and low toxicity. This review examines the conventional peptide‐loaded carrier fabrication process and its current limitations.
Wookyoung Jang, Ki Wan Bong
wiley +1 more source
Signaling roles of ceramide and its metabolites in cutaneous antimicrobial defense
Dermatologica Sinica, 2015 The skin epidermis is a multipurpose barrier (i.e., against epidermal permeability disruption and oxidative/UV irradiation) as well as a mechanical barrier and antimicrobial barrier, to protect cells/tissues from external perturbants.
Yoshikazu Uchida +2 more
doaj +1 more source
Tissue-Specific Transcriptomes Reveal Gene Expression Trajectories in Two Maturing Skin Epithelial Layers in Zebrafish Embryos. [PDF]
, 2019 Epithelial cells are the building blocks of many organs, including skin. The vertebrate skin initially consists of two epithelial layers, the outer periderm and inner basal cell layers, which have distinct properties, functions, and fates.
Cokus, Shawn J +6 more
core +2 more sources
Multi‐Scale Interface Engineering of MXenes for Multifunctional Sensory Systems
Advanced Functional Materials, EarlyView.MXenes, as two‐dimensional transition metal carbides and nitrides, demonstrate remarkable capabilities for multifunctional sensing applications. This review systematically examines multi‐scale interface engineering approaches that enhance sensing performance, enable diverse detection functionalities, and improve system‐level compatibility in MXene ...
Jiaying Liao, Sin‐Yi Pang, Jianhua Hao
wiley +1 more source
Proteomic analysis of skin invasion by blood fluke larvae. [PDF]
, 2008 BackgroundDuring invasion of human skin by schistosome blood fluke larvae (cercariae), a multicellular organism breaches the epidermis, basement membrane, and dermal barriers of skin.
Braschi, Simon +7 more
core +1 more source
Epidermal Barrier Dysfunction in Atopic Dermatitis [PDF]
Journal of Investigative Dermatology, 2009 Atopic dermatitis (AD) is a multifactorial, heterogenous disease that arises as a result of the interaction between both environmental and genetic factors. Changes in at least three groups of genes encoding structural proteins, epidermal proteases, and protease inhibitors predispose to a defective epidermal barrier and increase the risk of developing ...
Cork, Michael J. +9 more
openaire +2 more sources
Advanced Functional Materials, EarlyView.Flexible piezoresistive pressure sensors underpin wearable and soft electronics. This review links sensing physics, including contact resistance modulation, quantum tunneling and percolation, to unified materials/structure design. We highlight composite and graded architectures, interfacial/porous engineering, and microstructured 3D conductive networks
Feng Luo +2 more
wiley +1 more source
Dermatitis and aging-related barrier dysfunction in transgenic mice overexpressing an epidermal-targeted claudin 6 tail deletion mutant. [PDF]
PLoS ONE, 2009 The barrier function of the skin protects the mammalian body against infection, dehydration, UV irradiation and temperature fluctuation. Barrier function is reduced with the skin's intrinsic aging process, however the molecular mechanisms involved are ...
Tammy-Claire Troy +4 more
doaj +1 more source
In vitro models of dermatophyte infection to investigate epidermal barrier alterations
Experimental Dermatology, 2018 Fungal infections of the skin, known as dermatophytoses, are initiated at the epidermal barrier and lead to dysfunctions of the stratum corneum and cornified skin appendages. Dermatophytosis affects a significant part of the human population and, despite
É. Faway +2 more
semanticscholar +1 more source