Results 291 to 300 of about 2,098,761 (326)

The epidermal permeability barrier

Anatomy and Embryology, 1988
The permeability barrier of the skin which prevents transcutaneous water loss and penetration of harmful drugs from the environment is localized in the horny layer of the epidermis. Multiple lipid bilayers obstructing the intercellular space of the stratum corneum fulfill this function.
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Development of the Epidermal Barrier

NeoReviews, 2001
After completing this article, readers should be able to: 1. Name the four epidermal strata. 2. List the epidermal stratum that is primarily deficient in the very low-birthweight preterm infant and its primary function. 3. Characterize the physiologic similarities between the developing skin and the developing lung. 4.
Steven B. Hoath, Vivek Narendran
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The Epidermal Barrier in Atopic Dermatitis

Seminars in Cutaneous Medicine and Surgery, 2008
Epidermal barrier function is abnormal in individuals with atopic dermatitis (AD). It is controversial whether primary epidermal barrier abnormalities alone account for the physiological and clinical abnormalities found in those persons with AD or whether the observed barrier dysfunction is a consequence of primary immunologic abnormalities.
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Epidermal barrier and oxidative stress parameters improve during in 311 nm narrow band UVB phototherapy of plaque type psoriasis.

Journal of dermatological science (Amsterdam), 2018
BACKGROUND Psoriasis is a multi-systemic inflammatory disease that results from dysregulation between epidermal keratinocyte homeostasis and both innate and acquired immunity. Epidermal barrier defect has been described in psoriatic lesions.
R. Darlenski, E. Hristakieva, U. Aydın, Desisslava Gancheva, T. Gancheva, A. Zheleva, V. Gadjeva, J. Fluhr   +7 more
semanticscholar   +1 more source

Toxicity of Graphene Oxide in Nematodes with a Deficit in the Epidermal Barrier Caused by RNA Interference Knockdown of unc-52

Environmental Science and Technology Letters, 2018
The epidermal barrier is important for the defense of environmental organisms against the damage from engineered nanomaterials (ENMs). We employed Caenorhabditis elegans to examine the possible influence of a deficit in the epidermal barrier caused by ...
Xuecheng Ding, Q. Rui, Yunli Zhao, Huimin Shao, Yiping Yin, Qiuli Wu, Dayong Wang   +6 more
semanticscholar   +1 more source

Epidermal barrier in disorders of the skin

Microscopy Research and Technique, 1997
The water permeability barrier of the stratum corneum (SC) seems primarily to be regulated by the lamellarly arranged lipid bilayers between the corneocytes, which originate largely from polar lipid precursors provided by the cells of stratum granulosum via exocytosis of the lamellar body (LB) content.
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Epidermal barrier function and systemic diseases

Clinics in Dermatology, 2012
The skin is a vital organ for life and, among its many functions, the role as a protective barrier is one of the most important. It is the main boundary between the body and the external environment. As defensive barrier, the epidermis protects internal organs from physical and chemical trauma, microorganism invasion, and ultraviolet radiation. It also
Marcia, Ramos-e-Silva, Claudio de-Moura-Castro, Jacques   +1 more
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Role of the epidermal barrier in atopic dermatitis

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, 2009
SummaryThe skin's permeability barrier protects against extensive water loss and prevents the entry into the skin of harmful substances like irritants, allergens and microorganisms. The permeability barrier is mainly located in the stratum corneum and consists of corneocytes and a lipid‐enriched intercellular domain.
Ehrhardt, Proksch, Regina, Fölster-Holst, Matthias, Bräutigam, Marjan, Sepehrmanesh, Stephan, Pfeiffer, Jens-Michael, Jensen   +5 more
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Psychological stress and epidermal barrier function

Clinics in Dermatology, 2012
The skin is the organ that acts as a barrier between the outer and inner environments of the body. It is thus exposed not only to a wide variety of physical, chemical, and thermal insults from the outside world but also to inner endogenous stimuli. Stress, once an abstract psychologic phenomenon, has taken research's center stage in recent years.
Edith, Orion, Ronni, Wolf
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Epidermal impermeable barriers in mouse and fly

Current Opinion in Genetics & Development, 2005
Despite significant structural differences, the surface epithelia of flies and mice exhibit remarkable functional parallels. Genetic studies in both organisms have identified highly conserved pathways regulating cell movement and polarity, wound healing, innate immunity and appendage formation.
Stephen M, Jane, Stephen B, Ting, John M, Cunningham   +2 more
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