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Abnormal epidermal barrier in the pathogenesis of psoriasis
Clinics in Dermatology, 2012Almost 2 decades ago, Williams and Elias suggested a unifying concept for the pathogenesis of disorders of cornification, according to which the integrity of the epidermal barrier and its effective function is an important factor in the regulation of epidermal DNA synthesis.
Wolf R +3 more
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Ultrastructure of the epidermal barrier after irritation
Microscopy Research and Technique, 1997The stratum corneum (SC) controls the diffusion and penetration of chemical substances and drugs into and through the skin. Surprisingly, knowledge of the SC structure and reaction to the various irritants is still poorly understood. Routine transmission electron microscopy has not been effective in demonstrating the epidermal lipids (EL) of SC which ...
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Location and nature of the epidermal permeability barrier
International Journal of Cosmetic Science, 1986SynopsisThe lowest region of human and pig stratum corneum has been isolated as an integral layer, referred to as the stratum compactum. This preparation is resistant to disruption by enzymes, 6M urea, Triton X‐100 and organic solvents. Our evidence suggests that penetration of materials to and through the corneum depend on the state of cohesion ...
P A, Bowser, R J, White, D H, Nugteren
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The Epidermal Barrier to Schistosoma mansoni Infection*
2015The stratified epithelium serves as protection for underlying tissues and organs, and the structural fitness of the epidermal cells has been extensively reported. We studied the possible roles played by the epidermis as a barrier against the migration of Schistosoma mansoni larvae.
K, Fukuyama +3 more
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Effect of moisturizers on epidermal barrier function
Clinics in Dermatology, 2012A daily moisturizing routine is a vital part of the management of patients with atopic dermatitis and other dry skin conditions. The composition of the moisturizer determines whether the treatment strengthens or deteriorates the skin barrier function, which may have consequences for the outcome of the dermatitis.
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