Results 101 to 110 of about 42,895 (279)

CRISPR/Cas9‐mediated Genome‐editing Reveals 10 Testis‐enriched Genes and One Non‐testis‐enriched Gene are Dispensable for Male Fecundity in Mice

Andrology, EarlyView.
ABSTRACT Background More than 1000 genes have been identified as predominantly expressed in the human testis. Advances in gene editing technologies have enabled the rapid and efficient generation of genetically engineered mice. This approach facilitates the screening of genes essential for spermatogenesis by analyzing knockout mouse models.
Yumiao Qiu, Keisuke Shimada, Masahito Ikawa   +2 more
wiley   +1 more source

Histology analysis of testis and epididymis.

, 2017
(A to D) Gross appearance of the testis and epididymis. WT (A), Zfy-1 knockout (KO) (B), Zfy2-KO (C), Zfy1 and Zfy2 double knockout (Zfy1/2-DKO) (D). (E) Testis weight of WT, Zfy1-KO and 2-KO, and 1/2-DKO mice. Error bars: S.D., n = 3.
Atsuo Ogura (102448), Tomomi Kato (121027), Hiroshi Asahara (289520), Hiromitsu Tanaka (165959), Kenji Miyado (412327), Kumiko Shiozawa (3692548), Tadashi Kondo (447840), Tomoki Chiba (390388), Toshiro Kubota (522192), Kenji Yamatoya (3692539), Takashi Nakasuji (3692542), Narumi Ogonuki (247405), Naoyuki Miyasaka (3692545)   +12 more
core   +1 more source

Seminal Plasma Exosomal miRNA Profiling Reveals hsa‐miR‐7‐5p as a Key Regulator of Sperm Motility in Asthenozoospermia

Andrology, EarlyView.
ABSTRACT Background Asthenozoospermia is a significant contributing factor to male infertility. Accumulating evidence indicates that impaired sperm motility is closely linked to dysregulated microRNA expression during spermatogenesis. Seminal plasma exosomes are enriched with diverse microRNAs, which play pivotal roles in modulating sperm motility, the
Zhi‐Jian Zhu, Meng‐Li Cui, Wen‐Jing Yuan, Jia‐Ning Zhang, Shuo Zhang, Xi‐Qiao Yao, Ruo‐Qing Li, Jin‐Feng Li, En‐Zhong Li   +8 more
wiley   +1 more source

Postoperative testicular metastasis in early to mid-stage gastric adenocarcinoma: a case report and literature review

Frontiers in Oncology
This study reports a case of a 59-year-old male who primarily presented with a testicular mass accompanied by pain, ultimately diagnosed as testicular metastasis from gastric adenocarcinoma.
Yuanshun Huang, Mengshuang Xu, Yaoyu Zhang, Yuan Xue, Lijun Wang, He Huang, Wei Li, Shadan Li   +7 more
doaj   +1 more source

Comprehensive Quantification of Oligoasthenozoospermia Induced by Obesity, Reproductive Toxicants, and Their Combination in Rat Models

Andrology, EarlyView.
ABSTRACT Background Oligoasthenozoospermia is a leading cause of male infertility and has been increasingly associated with the global surge in obesity and exposure to reproductive toxicants. Despite extensive research on each factor individually, their combined pathological effects remain poorly understood.
Yunlong Yao, Xi Zhang, Lingru Li, Yunzhi Zhang, Shuo Huang, Yulin Zong, Mingrui Li, Fufangyu Zhao, Linghui Zhu, Tianxing Li, Wenlong Sun, Mingyan Shao, Yanfei Zheng   +12 more
wiley   +1 more source

Cysts in the Epididymis [PDF]

, 1961
The following conclusions were drawn from literary r eviews as well as pathohistological studies on 6 cases of cysts in the epididymis which were experienced in recent 1 year and a half. 1) We agree with kobayashi and Miyawaki who have assigned the term "
水本, 龍助, 平間, 茂
core  

Immunolocalization of HIBADH in bull seminiferous epithelium and epididymis.

, 2015
(A, B, C, and D) Localization of HIBADH in adult bull testis, caput epididymis, corpus epididymis, and cauda epididymis, respectively. The brown area indicates the expressed protein, whereas the blue area is the nuclear DNA signal (negative control ...
Qiang Jiang (764314), Jinming Huang (390392), Yan Zhang (8098), Changfa Wang (390394), Yan Sun (22436), Chunhong Yang (764312), Jifeng Zhong (312141), Xiuge Wang (764313), Shuai Zhang (115662), Zhihua Ju (390391)   +9 more
core   +1 more source

A Unified Machine Learning Model for Relapse Prediction in Clinical Stage I Testicular Cancer

Andrology, EarlyView.
ABSTRACT Background Approximately one‐fourth of patients with clinical stage I testicular cancer relapse. For decades, risk stratification has been based on different tumor characteristics for seminomas and non‐seminomas. Previous studies primarily used Cox proportional‐hazards models and included only a limited number of variables.
Thomas Wagner, Ramtin Zargari Marandi, Jakob Lauritsen, Daniel Dawson Murray, Mikkel Bandak, Birgitte Grønkær Toft, Dan Berney, Gedske Daugaard   +7 more
wiley   +1 more source

Testicular SIRT1 Loss Reveals an Aging‐Like Proteomic Landscape and Precipitates Reproductive Deterioration

Andrology, EarlyView.
ABSTRACT Background Advanced paternal age is associated with reduced male fertility and testicular dysfunction. Among the molecular regulators involved in aging, SIRT1, a NAD+‐dependent deacetylase, plays a pivotal role in maintaining oxidative balance and cellular homeostasis.
María Iniesta‐Cuerda, Jiřina Havránková, Hedvika Řimnáčová, Jiří Moravec, František Liška, Martin Knytl, Milena Králíčková, Jan Nevoral   +7 more
wiley   +1 more source

In vitro assessment of di(2-ethylhexyl) phthalate effect on epididymal sperm quality in dromedary camels

Open Veterinary Journal
Background: Di(2-ethylhexyl) phthalate (DEHP), a commonly used plasticizer and endocrine disruptor, has been implicated in various reproductive disorders in farm animals.
Dina E. M. Rashad, Ahmed S. A. Sosa, Seham F. Shehata, Karima Gh. M. Mahmoud, Mohamed M. M. El-Sokary   +4 more
doaj   +1 more source