Results 251 to 260 of about 75,278 (356)

Local Anesthetics in Cancer: Mechanisms and Translational Perspectives

open access: yesMedComm – Oncology, Volume 5, Issue 1, March 2026.
Local anesthetics demonstrate multifaceted antitumor effects that collectively contribute to cancer suppression. Beyond canonical sodium channel blockade, these agents exert the following pharmacological actions: inhibition of tumor cell proliferation, suppression of migration and invasion, induction of proapoptotic pathways, attenuation of ...
Wan‐li Wang   +4 more
wiley   +1 more source

Diagnosing Breastfeeding Difficulties: Where Do We Stand?

open access: yesMaternal &Child Nutrition, Volume 22, Issue 1, March 2026.
ABSTRACT Despite lactation being a natural occurrence in mammals, many structural barriers and individual factors can impact the ability of a woman to breastfeed her newborn. At the individual level, evidence has widely documented several risk factors and societal barriers for impaired lactation, many of which have been steeply increasing in human ...
Laura Galante   +2 more
wiley   +1 more source

What Is My Role? A Qualitative Study of Labor, Birth, and Postpartum Experiences of Partners

open access: yesNursing &Health Sciences, Volume 28, Issue 1, March 2026.
ABSTRACT This study explores partners' roles during labor, birth, and the postpartum period, and the factors influencing their performance. A qualitative interpretive phenomenological approach was adopted to explore participants' lived experiences. A total of 31 partners participated in semi‐structured face‐to‐face interviews using open‐ended questions.
Beatriz Pereda‐Goikoetxea   +4 more
wiley   +1 more source

Impaired adrenergic regulation of Kv channels underlies LC hyperactivity and early‐onset sleep disruption in AD‐like amyloidogenic mice

open access: yesAlzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Sleep–wake disturbances frequently occur at early stages of Alzheimer's disease (AD) and accelerate disease progression, but the underlying neural mechanisms are not fully understood. METHODS We examined sleep–wake behavior and locus coeruleus (LC) activity in young 5xFAD mice using electrophysiology and pharmacological approaches
Yi‐Ci Zhang   +5 more
wiley   +1 more source

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