Results 61 to 70 of about 5,295,306 (255)

Radiculopathy as Delayed Presentations of Retained Spinal Bullet. [PDF]

open access: yes, 2015
Bullet injuries to the spine may cause injury to the anatomical structures with or without neurologic deterioration. Most bullet injuries are acute, resulting from direct injury. However, in rare cases, delayed injury may occur, resulting in claudication.
Choi, Man Kyu   +3 more
core   +1 more source

Targeted senotherapy improves electrographic and behavioral outcomes in a mouse model of temporal lobe epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Current pharmacotherapy for temporal lobe epilepsy (TLE) is limited to symptomatic treatment and leaves approximately one third of patients with inadequate seizure control. Discovering disease‐modifying targets is an unmet clinical need. We have previously identified senescent cells (SCs) as one such target. Many drugs that eliminate
David J. McFall   +3 more
wiley   +1 more source

Enhancing Nervous System Recovery through Neurobiologics, Neural Interface Training, and Neurorehabilitation. [PDF]

open access: yes, 2016
After an initial period of recovery, human neurological injury has long been thought to be static. In order to improve quality of life for those suffering from stroke, spinal cord injury, or traumatic brain injury, researchers have been working to ...
Edgerton, V Reggie   +4 more
core   +1 more source

Dual role of spreading depolarization in an epileptic focus

open access: yesEpilepsia, EarlyView.
Abstract Objective Spreading depolarizations (SDs) are often associated with epileptic discharges. Although SDs are traditionally thought to contribute to postictal depression and termination of epileptic discharges, seizures may also occur during SDs or may even follow SDs, suggesting that interactions between SD and seizures are more complex.
Daria Vinokurova   +3 more
wiley   +1 more source

Electrode geometry and preferential stimulation of spinal nerve fibers having different orientations: a modeling study [PDF]

open access: yes, 1992
In a computer modeling study of epidural spinal cord stimulation using a longitudinal array of electrode contacts, the effect of contact geometry and contact combination on the threshold voltages for stimulation of dorsal column (DC) fibers and dorsal ...
Holsheimer, Jan, Struijk, Johannes J.
core   +2 more sources

An algorithm for seizure detection in rodents

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Epilepsy animal research often relies on long‐term intracranial electroencephalographic (iEEG) recordings. Here, we describe an artificial neural network (ANN) algorithm for automatic detection of seizures. Methods The algorithm was trained on iEEG recordings of three mouse models of chronic epilepsy: (1) the pilocarpine model of ...
Lyna Kamintsky   +9 more
wiley   +1 more source

Absence seizures: Update on signaling mechanisms and networks

open access: yesEpilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Brain–Computer Interfaces: The Dawn of a New Era in Disease Treatment

open access: yesExploration, EarlyView.
This study investigates the potential of brain–computer interface (BCI) technology in treating neuropsychiatric disorders, such as movement and communication barriers. Our review examines the history, signal paradigms, and diverse applications of BCI while also discussing ongoing research into novel materials and emerging technologies that offer ...
Yuqi Feng   +11 more
wiley   +1 more source

Fascia‐Fat‐Fascia “Sandwich Graft” Decreases Postoperative Cerebrospinal Fluid Leak Rate for High‐Flow Skull Base Defects

open access: yes
International Forum of Allergy &Rhinology, EarlyView.
Vidit M. Talati   +11 more
wiley   +1 more source

Surgical Treatment of Lateral Skull Base Tumors Extending to the Craniovertebral Junction

open access: yesHead &Neck, EarlyView.
ABSTRACT Objective To evaluate the clinical manifestation, surgical strategies, and long‐term outcomes of lateral skull base tumors extending to the craniovertebral junction (CVJ), with a focus on the infratemporal fossa approach (IFA) and individualized treatment options for cervical‐occipital stability.
Songbo Xue   +14 more
wiley   +1 more source

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