Results 301 to 310 of about 849,922 (340)

A New Look at the Role of Radiation-Related Epigenetic Mechanisms in Diagnosis and Anticancer Therapies. [PDF]

Cells
Olichwier AJ, Bruzgo-Grzybko M, Kalita IS, Bielicka N, Chabielska E, Gromotowicz-Poplawska A.   +5 more
europepmc   +1 more source

Epigenetic Applications in Adverse Outcome Pathways and Chemical Risk Evaluation [PDF]

, 2017
Allard, P, Angrish, M, Chadwick, LH, Chorley, BN, Hines, E, McCullough, SD   +5 more
core  

Human Atlas of Tooth Decay Progression: Identification of Cellular Mechanisms Driving the Switch from Dental Pulp Repair Toward Irreversible Pulpitis

Advanced Science, EarlyView.
Tooth decay progression transforms the dental pulp response from repair to fibrosis. At early stages, stromal cells reprogram to repair the extra cellular matrix (ECM), blood vessels, and nerves, remodel and grow, keeping repair possible. In advanced decay, hypoxia, and vessel regression, in complement with an immune switch, fuel nerve degeneration and
Hoang Thai Ha, Sofya Kosmynina, Amandine Verocq, Keremsah Ozen, Ines Tekia, Hugo Bussy, Marie Ramirez, Dima Sabbah, Chloe Goemans, Valerie Vandenbempt, Esteban N. Gurzov, Sumeet Pal Singh, Nicolas Baeyens   +12 more
wiley   +1 more source

Using epigenetic clocks in environmental epigenetics: recommendations for estimating biological aging in perinatal and pediatric samples. [PDF]

Essays Biochem
England-Mason G.
europepmc   +1 more source

Heat Stress Modulates WDR5‐Mediated H3K4me3 Modification to Induce Melanogenesis via Activating CX3CL1/CX3CR1 Axis

Advanced Science, EarlyView.
This study elucidates the mechanism by which heat stress regulates skin pigmentation: heat stress upregulates CX3CL1 through the MYC‐WDR5‐H3K4me3 axis, thereby activating the CX3CL1/CX3CR1‐JNK signaling pathway and ultimately promoting melanogenesis. These findings provide novel potential therapeutic targets for pigmentary skin disorders.
Yushan Zhang, Ling Jiang, Yibo Hu, Chuhan Fu, Jinhua Huang, Jing Chen, Qinghai Zeng   +6 more
wiley   +1 more source

Dental Ageing Offers New Insights Into the First Epigenetic Clock for Common Dolphins (<i>Delphinus delphis</i>). [PDF]

Ecol Evol
Hanninger EF, Peters KJ, Gerber L, Barratclough A, Betty EL, Palmer EI, Horvath S, Stockin KA.   +7 more
europepmc   +1 more source

PLA2G16‐Mediated Tetracosatetraenoic Acid Rewires Fatty Acid Oxidation to Impair CD8+ T Cell Immune Function in Promoting Breast Cancer Lung Metastasis

Advanced Science, EarlyView.
Illustrating how tumor‐derived PLA2G16 regulates tetracosatetraenoic acid (C24:4 (n‐6)) accumulation and CD8+ T cell activation via the C24:4‐PPARα‐FAO axis in early metastatic niches, thereby promoting lung metastasis of triple‐negative breast cancer.
Yubi Gan, Die Meng, Lei Lang, Jing Luo, Peijin Dai, Chao Chang, Zexiu Lu, Yuetong Guo, Rui Wang, Shanchun Chen, Xi Tang, Yixuan Hou, Dongmei Tan, Manran Liu   +13 more
wiley   +1 more source

Editorial: Epigenetic and metabolic regulators of breast carcinogenesis, volume II. [PDF]

Front Oncol
Saber-Ayad M, Elemam NM, Talaat IM, Busch H.   +3 more
europepmc   +1 more source

Anesthetics and epigenetics

Oncotarget, 2016
openaire   +2 more sources