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Genetic Variations in Vitamin D Metabolism Linking Epigenetic Regulation and Microbiota Interactions: From Phenotype to Genotype. [PDF]
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Targeting the epigenome and tumor heterogeneity: advances in immunotherapy for chemoresistant metastatic colorectal cancer. [PDF]
Front ImmunolCao Y +7 more
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Neurochemistry International, 2021
Substance use disorders are complex biopsychosocial disorders that have substantial negative neurocognitive impact in various patient populations. These diseases involve the compulsive use of licit or illicit substances despite adverse medicolegal consequences and appear to be secondary to long-lasting epigenetic and transcriptional adaptations in ...
Jean Lud, Cadet, Subramaniam, Jayanthi
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Substance use disorders are complex biopsychosocial disorders that have substantial negative neurocognitive impact in various patient populations. These diseases involve the compulsive use of licit or illicit substances despite adverse medicolegal consequences and appear to be secondary to long-lasting epigenetic and transcriptional adaptations in ...
Jean Lud, Cadet, Subramaniam, Jayanthi
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Nature Biotechnology
Epigenetics is the study of heritable changes to the genome and gene expression patterns that are not caused by direct changes to the DNA sequence. Examples of these changes include posttranslational modifications to DNA-bound histone proteins, DNA methylation, and remodeling of nuclear architecture.
Rajan, Jain, Jonathan A, Epstein
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Epigenetics is the study of heritable changes to the genome and gene expression patterns that are not caused by direct changes to the DNA sequence. Examples of these changes include posttranslational modifications to DNA-bound histone proteins, DNA methylation, and remodeling of nuclear architecture.
Rajan, Jain, Jonathan A, Epstein
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Maturitas, 2013
Over the past two decades, a growing interest on the research of the biological basis of human longevity has emerged, in order to clarify the intricacy of biological and environmental factors affecting (together with stochastic factors) the quality and the rate of human aging. These researches have outlined a complex scenario in which epigenetic marks,
D'Aquila P +3 more
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Over the past two decades, a growing interest on the research of the biological basis of human longevity has emerged, in order to clarify the intricacy of biological and environmental factors affecting (together with stochastic factors) the quality and the rate of human aging. These researches have outlined a complex scenario in which epigenetic marks,
D'Aquila P +3 more
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Epigenetics and atherosclerosis
Biochimica et Biophysica Acta (BBA) - General Subjects, 2009The contribution of epigenetic mechanisms to cardiovascular diseases remains poorly understood. Hypomethylation of genomic DNA is present in human atherosclerotic lesions and methylation changes also occur at the promoter level of several genes involved in the pathogenesis of atherosclerosis, such as extracellular superoxide dismutase, estrogen ...
Mikko P, Turunen +2 more
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Pancreatology, 2007
'Epigenetics', the term that is used for the study of heritable changes in gene function that occur without a change in the DNA sequence, has become a significant area of research. As a consequence of this emerging field, our concepts founded upon genetics alone have been blurred and the way researchers think about heredity has changed.
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'Epigenetics', the term that is used for the study of heritable changes in gene function that occur without a change in the DNA sequence, has become a significant area of research. As a consequence of this emerging field, our concepts founded upon genetics alone have been blurred and the way researchers think about heredity has changed.
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WIREs Systems Biology and Medicine, 2016
Why do we grow up to have the traits we do? Most 20th century scientists answered this question by referring only to our genes and our environments. But recent discoveries in the emerging field of behavioral epigenetics have revealed factors at the interface between genes and environments that also play crucial roles in development.
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Why do we grow up to have the traits we do? Most 20th century scientists answered this question by referring only to our genes and our environments. But recent discoveries in the emerging field of behavioral epigenetics have revealed factors at the interface between genes and environments that also play crucial roles in development.
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Pharmacopsychiatry, 2012
Investigations on gene variants as milestones in the development of schizophrenia have not fulfilled the enormous, initial expectations. Neither candidate gene approaches trying to associate single genes with the disorder, nor genome-wide association studies (GWAS), that have been welcomed more recently with great enthusiasm, could end the general ...
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Investigations on gene variants as milestones in the development of schizophrenia have not fulfilled the enormous, initial expectations. Neither candidate gene approaches trying to associate single genes with the disorder, nor genome-wide association studies (GWAS), that have been welcomed more recently with great enthusiasm, could end the general ...
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Journal of the European Academy of Dermatology and Venereology, 2011
AbstractIncreasing evidence indicates that epigenetic mechanisms are involved in the pathogenesis of autoimmune rheumatic diseases such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). The pathogenesis of the organ‐specific autoimmune disease psoriasis, however, remains poorly understood.
P, Zhang, Y, Su, Q, Lu
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AbstractIncreasing evidence indicates that epigenetic mechanisms are involved in the pathogenesis of autoimmune rheumatic diseases such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). The pathogenesis of the organ‐specific autoimmune disease psoriasis, however, remains poorly understood.
P, Zhang, Y, Su, Q, Lu
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