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Epigenetics and Regeneration

2012
During newt lens regeneration a unique transdifferentiation event occurs. In this process, dorsal iris pigmented epithelial cells transdifferentiate into lens cells. This system should provide a new insight into cellular plasticity in basic and applied research.
Nobuyasu, Maki, Hironobu, Kimura
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Epigenetics in lupus

Annals of the New York Academy of Sciences, 2011
Accumulating epidemiological, clinical, and experimental evidence supports the conclusion of a critical role of epigenetic factors in immune programming. This understanding provides the basis for elucidating how the intricate interactions of the genome, epigenome, and transcriptome shape immune responses and maintain immune tolerance to self‐antigens ...
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The Evolution of Epigenetics

Perspectives in Biology and Medicine, 2014
Early studies of the developing embryo raised the question of how a fertilized egg could give rise to a complex multicellular organism containing many different kinds of cells. The term epigenetics originally referred to the study of these processes.
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Epigenetics of Obesity

2014
Among different mechanisms that could lead to interindividual differences in obesity susceptibility, epigenetics has emerged, in the last years, as a potentially very important contributor. The role of epigenetics in obesity may be considered by different points of view.
FRISO, Simonetta, Sang Woon Choi
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Epigenetic Inhibitors

2014
Traditional treatments for cancer include chemotherapy, radiation therapy, and surgery. Recently, epigenetic inhibitors have been found to be very effective in cancer treatment. Epigenetic changes such as DNA methylation, histone deacetylation, and microRNA (miRNA) expression are capable of silencing the expression of tumor suppressor genes and ...
Mukesh, Verma, Hirendra Nath, Banerjee
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Epigenetics

Biochimie, 2012
Paola B, Arimondo   +2 more
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Asthma Epigenetics

2013
Asthma is the most common chronic disease of childhood, and a growing body of evidence indicates that epigenetic variations may mediate the effects of environmental exposures on the development and natural history of asthma. Epigenetics is the study of mitotically or meiotically heritable changes in gene expression that occur without directly altering ...
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