Results 351 to 360 of about 52,554 (369)
Some of the next articles are maybe not open access.
2010
Cancer is a heterogeneous disease caused largely by abnormalities of the genome and the epigenome. Typically, such abnormalities include genetic changes such as mutations and other genomic rearrangements or epigenetic changes such as aberrant DNA methylation and histone modifications that are frequently mediated by exposure to environmental or ...
Chris Boshoff +2 more
openaire +3 more sources
Cancer is a heterogeneous disease caused largely by abnormalities of the genome and the epigenome. Typically, such abnormalities include genetic changes such as mutations and other genomic rearrangements or epigenetic changes such as aberrant DNA methylation and histone modifications that are frequently mediated by exposure to environmental or ...
Chris Boshoff +2 more
openaire +3 more sources
2011
The development of male germ cells from the primordial germ cell stage to that of the mature spermatozoon is a key time of epigenetic reprogramming. Orchestrated by specialized enzymes, DNA methylation and histone modifications undergo dynamic changes throughout gametogenesis. Alterations to any level of the sperm epigenetic coding may affect fertility
Jacquetta M. Trasler, Donovan Chan
openaire +2 more sources
The development of male germ cells from the primordial germ cell stage to that of the mature spermatozoon is a key time of epigenetic reprogramming. Orchestrated by specialized enzymes, DNA methylation and histone modifications undergo dynamic changes throughout gametogenesis. Alterations to any level of the sperm epigenetic coding may affect fertility
Jacquetta M. Trasler, Donovan Chan
openaire +2 more sources
Interpreting type 1 diabetes risk with genetics and single-cell epigenomics
Nature, 2021Alexander Kleger +2 more
exaly
Regulatory genomic circuitry of human disease loci by integrative epigenomics
Nature, 2021Benjamin T James +2 more
exaly
Single-cell epigenomics reveals mechanisms of human cortical development
Nature, 2021Amy B Wilfert +2 more
exaly
Single-cell epigenomics: techniques and emerging applications
Nature Reviews Genetics, 2015Omer Schwartzman, Amos Tanay
exaly
The NIH Roadmap Epigenomics Mapping Consortium
Nature Biotechnology, 2010Bradley E Bernstein +2 more
exaly
Folate and fetal programming: a play in epigenomics?
Trends in Endocrinology and Metabolism, 2013Jean-louis Guéant +1 more
exaly