Results 21 to 30 of about 4,983 (178)

Epilepsia focal asociada a tumor cerebral

open access: yesALERTA Revista Científica del Instituto Nacional de Salud, 2018
La epilepsia es una enfermedad neurológica crónica frecuente. La Organización Mundial de la Salud ha reportado a la fecha, cerca de 50 millones de casos en el mundo, de los cuales, el 85% proviene de países en desarrollo.1 Según el origen de la actividad epiléptica, se clasifica en focal y generalizada, y según la etiología, en estructural, genética ...
openaire   +2 more sources

A phase 3, randomized clinical trial of soticlestat as adjunctive therapy for Lennox–Gastaut syndrome

open access: yesEpilepsia, EarlyView.
Soticlestat as adjunctive therapy for Lennox–Gastaut syndrome. Abstract Objective There remains a need for new treatments for Lennox–Gastaut syndrome (LGS), a developmental and epileptic encephalopathy with a heterogenous patient population that often requires polytherapy. The phase 3, randomized SKYWAY study (NCT04938427) investigated the efficacy and
Renzo Guerrini   +15 more
wiley   +1 more source

Paroxismos occipitais após o fechamento dos olhos: correlações clínico-eletrencefalográficas em 24 casos

open access: yesArquivos de Neuro-Psiquiatria, 1994
Paroxismos occipitais aparecendo com o fechamento dos olhos (POFO) constituem o padrão eletrencefalográfico fundamental da epilepsia idiopática da infância com paroxismos occipitais (EIIPO).
Lineu Corrêa Fonseca   +1 more
doaj   +1 more source

Epileptogénesis y corteza piriforme: entendiendo a la epilepsia del lóbulo temporal más allá del hipocampo

open access: yesActa Neurológica Colombiana, 2023
Introducción: con la experiencia de los registros electroencefalográficos invasivos y el fracaso quirúrgico después de la cirugía, se ha hecho evidente que la epilepsia del lóbulo temporal es mucho más compleja de lo que se creía, y en la actualidad es ...
Camilo Espinosa Jovel   +1 more
doaj   +1 more source

Epilepsy in emerging adulthood: Clinical, psychosocial, and surgical challenges

open access: yesEpilepsia, EarlyView.
Abstract Objective Emerging adulthood (EAs; ages 19–29 years) is a unique developmental stage marked by major psychological, social, and occupational transitions. We sought to characterize the clinical, psychosocial, and surgical features of epilepsy in emerging adulthood, considering both current age and age at epilepsy onset.
Graham A. McLeod   +26 more
wiley   +1 more source

22181 - ¿FOCAL O GENERALIZADA? UN RETO DIAGNÓSTICO EN EPILEPSIA

open access: yesNeurology Perspectives
M. Freire Lázaro   +9 more
doaj   +2 more sources

Teaching Video Neuro Images : Epilepsia partialis continua in an adolescent with preexisting focal epilepsy [PDF]

open access: yesNeurology, 2017
A 15-year-old girl, with an 8-year history of well-controlled focal epilepsy, moderate intellectual disability, and neuropsychiatric problems (aggression and disinhibition), presented with continuous semirhythmic repetitive movement of the left hand (video at [Neurology.org][1]).
Niamh C, Lagan   +3 more
openaire   +2 more sources

Systematic statistical analysis of change in SEIzure interVAL with diazepam nasal spray supports this novel clinical endpoint for immediate‐use seizure medication

open access: yesEpilepsia, EarlyView.
Abstract Objective Appropriate endpoints for daily antiseizure medications may differ from those for intermittent, immediate‐use seizure medications (ISMs). The observed interval between seizure clusters over time (SEIzure interVAL [SEIVAL]) has been proposed as a novel effectiveness endpoint for ISMs.
Wesley T. Kerr   +4 more
wiley   +1 more source

Seizures in the Emergency Department: clinical and diagnostic data from a series of 153 patients

open access: yesNeurología (English Edition), 2023
Introduction: Seizures are a frequent reason for admission to emergency departments and require early, precise diagnosis and treatment. The objective of this study was to describe the clinical and prognostic characteristics of a series of patients with ...
V. Gajate-García   +7 more
doaj   +1 more source

Listening across frequencies: Capturing seizures of all patients to advance antiseizure medication development

open access: yesEpilepsia, EarlyView.
Abstract Seizure frequency has been the primary endpoint in epilepsy trials, with enrollment usually requiring ≥4 seizures per month. This threshold is more and more misaligned with clinical reality, as the availability of more treatment options has reduced baseline seizure burden, with a risk of excluding a proportion of patients from trials. Although
Stéphane Auvin, Jacqueline French
wiley   +1 more source

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