Results 141 to 150 of about 3,955,077 (290)

Adaptive Network Stabilization Despite Profound Structural Reorganization in Human Organotypic Cultures

Advanced Science, EarlyView.
Adult human organotypic cortical slices undergo marked neuronal loss, laminar disruption, and glial activation, yet their network activity progressively stabilizes after a variable period. Electrophysiology, longitudinal calcium imaging, and quantitative histology show that structurally remodeled human circuits show adaptive capacity resulting in ...
Estilla Zsófia Tóth, Rebeka Stelcz, Réka Bod, Ábel Petik, Eszter Juhász, Kinga Tóth, Liza Szalai, Nour Essam, Fanni Somogyi, Beatrix Kovács, Amirmahdi Mojtahedzadeh, Attila György Bagó, Loránd Erőss, Péter Orbay, Johanna Petra Szabó, Dániel Fabó, Boglárka Hajnal, Bence Rácz, Daniel Hillier, István Ulbert, Lucia Wittner   +20 more
wiley   +1 more source

Pattern avoidance in partial permutations [PDF]

, 2011
Motivated by the concept of partial words, we introduce an analogous concept of partial permutations. A partial permutation of length n with k holes is a sequence of symbols $\pi = \pi_1\pi_2 ...
Claesson, A., Jelinkova, E., Jelinek, V., Kitaev, S.   +3 more
core   +2 more sources

Printing‐Assisted Integration of Thermal, Fluidic and Electrical Components in Implants for Focal Brain Cooling

Advanced Science, EarlyView.
Extrusion‐based 3D printing of silicones and discrete electronic components are combined to create cortical implants for rodents that integrate thermal neuromodulation and electrical recording. Linked to an autonomous auxiliary driver unit, the system enables rapid, stable and localized hypothermia alongside ECoG recording.
Spencer Ryan Moore, Naomi King, Aruã Clayton Da Silva, Clare Howarth, Jason Berwick, Thomas E. Paterson, Ivan R. Minev   +6 more
wiley   +1 more source

Genetic epilepsies. remarks on the proposed "organization of the Epilepsies"

, 2017
Introduction. Genetic findings in several epilepsy syndromes provide insights into the pathophysiology of specific subtypes of epilepsy and into mechanisms of epileptogenesis, because the genes encoding ion channels, and proteins associated to the ...
Wieser, Heinz Gregor
core   +1 more source

Clinical study of partial epilepsies occurring before two years of life

, 1997
We analyzed the clinical features of 13 cases (9 boys, 4 girls) with partial epilepsies occurring before 2 years of life. Eight patients developed epilepsy between 4 and 11 months of age (average, 10.9 months). Five patients had complex partial seizures (
Yamaguchi, Seiji, Kishi, Kazuko, Kimura, Masahiko, Takusa, Yuichi, Wakazono, Akihiro, Sejima, Hitoshi, Ito, Masatoshi   +6 more
core   +1 more source

Topiramate in Medically Intractable Partial Epilepsies: Double‐Blind Placebo‐Controlled Randomized Parallel Group Trial

Epilepsia, 1999

semanticscholar   +1 more source

Temporal‐Targeted Accelerated 40 Hz tACS Enhances Cognitive Function and Network Integration in Alzheimer's Disease: A Randomized Clinical Trial

Advanced Science, EarlyView.
Bilateral temporal accelerated 40‐Hz tACS improves cognitive function in patients with Alzheimer's disease. Resting‐state fNIRS identifies treatment‐related increases in frontotemporoparietal functional connectivity, which are associated with cognitive improvement. ABSTRACT The temporal lobes are key hubs for memory and cognition.
Rong Guo, Xingxing Li, Chenjun Zou, Chao Zheng, Xiaohong Wu, Xuechao Lu, Jiaying Yan, Junfang Zhang, Xiaoyan Luo, Shiwei Ye, Dongsheng Zhou   +10 more
wiley   +1 more source

Lactylation‐Mediated HER2 Stabilization Promotes Trastuzumab Resistance in Gastric Cancer

Advanced Science, EarlyView.
Warburg effect‐derived lactate drives HER2 lactylation and trastuzumab resistance. Mechanistically, AARS1‐mediated lactylation stabilizes HER2 by inhibiting USP11‐dependent degradation and concurrently promotes HER2‐EGFR interaction. Importantly, inhibiting HER2 lactylation resensitizes gastric cancer cells to trastuzumab.
Meng Qian, Tongguan Tian, Zhenxiang Wang, Huihui Sun, Ming Zong, Ying Chen, Jie Xiong, Ye Chen, Zhiqian Hu, Tianming Li, Yanping Xu, Shuchang Xu   +11 more
wiley   +1 more source

Clinical utility of eslicarbazepine: current evidence

Drug Design, Development and Therapy, 2015
Gaetano Zaccara,1 Fabio Giovannelli,1,2 Massimo Cincotta,1 Alessia Carelli,3 Alberto Verrotti31Department of Medicine, Unit of Neurology, Florence Health Authority, Florence, Italy; 2Department of Neuroscience, Psychology, Pharmacology and Child ...
Zaccara G, Giovannelli F, Cincotta M, Carelli A, Verrotti A   +4 more
doaj  

Benign childhood partial epilepsies: benign childhood seizure susceptibility syndromes.

Journal of Neurology Neurosurgery & Psychiatry, 1993
C. Panayiotopoulos
semanticscholar   +1 more source