Results 121 to 130 of about 493,538 (290)

Ultrafast oscillations in the human brain and their functional significance

open access: yesEpilepsia, EarlyView.
Abstract Objective The upper frequency limit of human brain activity remains unknown. Using ultrahigh sampling rate (≥20 kHz) intracranial microelectroencephalography, this study aimed to systematically explore and quantitatively characterize brain field oscillations beyond the established high‐frequency oscillation range (>2 kHz), and to determine ...
Milan Brázdil   +13 more
wiley   +1 more source

Application of HFO and scaling analysis of neuronal oscillations in the presurgical evaluation of focal epilepsy

open access: yesBrain Research Bulletin
Purpose: To explore the utility of high frequency oscillations (HFO) and long-range temporal correlations (LRTCs) in preoperative assessment of epilepsy.
Li-juan Shi   +5 more
doaj   +1 more source

Regional thalamic neuropathology in patients with hippocampal sclerosis and epilepsy: A postmortem study [PDF]

open access: yes, 2013
Purpose Clinical, experimental, and neuroimaging data all indicate that the thalamus is involved in the network of changes associated with temporal lobe epilepsy (TLE), particularly in association with hippocampal sclerosis (HS), with potential roles in ...
Martinian, L   +3 more
core  

Comparison of volume‐ and surface‐based magnetic resonance imaging morphometry algorithms in the detection of focal cortical dysplasia

open access: yesEpilepsia, EarlyView.
Abstract Objective Detection of focal cortical dysplasia (FCD) remains a major challenge in presurgical epilepsy diagnostics. Magnetic resonance imaging (MRI) morphometry increasingly improves lesion detection and postsurgical outcomes. The volume‐based Morphometric Analysis Program, version 2018 (MAP18) with integrated artificial neural network and ...
Lara Bücheler   +17 more
wiley   +1 more source

Mindfulness meditation increases interictal epileptiform discharges in meditation‐naïve surgical epilepsy patients

open access: yesEpilepsia, EarlyView.
Abstract Objective Meditation has widely recognized psychological and neuromodulatory benefits, yet its effects on epileptiform activity remain unclear. This study examined whether novice meditation modulates interictal epileptiform discharges (IEDs) in patients with drug‐resistant epilepsy using intracranial electroencephalography (iEEG).
Shweta Soni   +5 more
wiley   +1 more source

Paroxysmal slow waves mark ictal networks

open access: yesEpilepsia, EarlyView.
Abstract Objective Epilepsy diagnosis and treatment monitoring are hindered by the episodic, heterogeneous expression of seizures and by normal‐appearing scalp electroencephalography (EEG) in many patients. We previously described paroxysmal slow‐wave events (PSWEs), brief epochs of broadband slowing detectable on EEG in people with epilepsy.
Florent J. M. Boyer‐Aymé   +13 more
wiley   +1 more source

The dynamic functional connectivity peak index: Detection of interictal epileptic activity with fMRI

open access: yesEpilepsia, EarlyView.
Abstract Objective Epileptogenic zone (EZ) localization is crucial for surgical treatment of patients with medication‐resistant epilepsy. Although simultaneous electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) can detect interictal discharges for EZ localization, clinical adoption is limited by the need for specialized ...
Lucas E. Sainburg   +9 more
wiley   +1 more source

Gamma suppression correlates with thalamic stimulation therapeutic response in intractable epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective In patients with drug‐resistant epilepsy who undergo anterior nucleus of the thalamus (ANT) deep brain stimulation (DBS), efficacy is assessed months after therapy initiation and clinicians have no guidance when choosing stimulation parameters due to the lack of real‐time biomarkers.
Zachary T. Sanger   +10 more
wiley   +1 more source

Intermittent fasting with medium‐chain triglycerides in drug‐resistant epilepsy: A pilot crossover trial

open access: yesEpilepsia, EarlyView.
Abstract Objective Ketogenic dietary therapies can reduce seizure frequency in drug‐resistant epilepsy, but adherence to the classical ketogenic diet is often poor. Intermittent fasting supplemented with medium‐chain triglycerides (MCTs) may offer a more feasible and less restrictive alternative.
Wiebke Hahn   +11 more
wiley   +1 more source

Complementary predictive value of electromagnetic source imaging and hemodynamic responses in epilepsy surgery: A quantitative spatial analysis

open access: yesEpilepsia, EarlyView.
Abstract Objective Accurate presurgical evaluation should assess not only the location but also the spatial extent of epileptic activity relative to the surgical cavity, a practical approximation of the epileptogenic zone. We evaluated how electromagnetic source imaging (EMSI) and hemodynamic responses to epileptic discharges relate to the surgical ...
Chifaou Abdallah   +13 more
wiley   +1 more source

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