Results 81 to 90 of about 29,221 (266)

Ictal dancing following right temporal seizure onset—Evidence for a distributed network

Epileptic Disorders, EarlyView.
Leo Y. Zhang, German Garza‐Garcia, Alex Doyle, Irfan S. Sheikh   +3 more
wiley   +1 more source

Decoding epilepsy's molecular blueprint: Machine learning unravels transcriptomic subtypes and regulatory networks

Epilepsia, EarlyView.
Abstract Objective Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy. The molecular heterogeneity underlying DRE remains poorly defined, largely due to limited access to resected brain tissue and substantial genetic diversity.
Yanping Weng, Yu Ma, Wanwan Hou, Haibo Li, Yuanfeng Zhou, Rui Zhao, Hao Li, Lian Chen, Yangyang Ma, Li Jin, Yi Wang, Yu An   +11 more
wiley   +1 more source

The significance of multimodality approach in the management of non‐lesional drug‐resistant focal parietal lobe epilepsies

Epilepsia Open
Due to extensive connectivity of the parietal lobe, non‐lesional drug‐resistant (DRE) parietal lobe epilepsies (PLEs) are difficult to localize and often imitate other epilepsies.
Patrick Hartnett, Naseem Zomorodi, Howard P. Goodkin, Ifrah Zawar   +3 more
doaj   +1 more source

Long‐lasting remodeling of astrocytes in an Scna1+/− mouse model of Dravet syndrome

Epilepsia, EarlyView.
Abstract Objective Dravet syndrome (DS) is a prototypical developmental and epileptic encephalopathy caused by mutations in the SCN1A gene, leading to loss of function of the voltage‐gated sodium channel Naᵥ1.1. The latter causes early onset drug‐resistant seizures and enduring cognitive and behavioral deficits.
Athénaïs Genin, Alicia Janvier, Tristan Moujellil‐Legagneur, Marine Blaquière, Alexis Chaussy, Romane Privé, Fabrice Duprat, Massimo Mantegazza, Etienne Audinat, Nicola Marchi, Noémie Cresto   +10 more
wiley   +1 more source

A star in the daylight clinical vignette: Lesional focal epilepsy with cerebral accessory falx

Epileptic Disorders, EarlyView.
Kyle McGrath, Joel Kaye, John Paul Sheehy, Heather Ravvin McKee   +3 more
wiley   +1 more source

Contralateral language network integration predicts and protects against naming decline after temporal lobe resection

Epilepsia, EarlyView.
Abstract Objective Anterior temporal lobe resection (ATLR) is an effective treatment for drug‐resistant temporal lobe epilepsy (TLE) but carries a substantial risk of language impairment, particularly in naming. Understanding and predicting the impact of ATLR on language functions remains a major clinical challenge.
Karl‐Heinz Nenning, Karin Trimmel, Lisa Bartha‐Doering, Marc Berger, Matthias J. Koepp, Georg Langs, Gregor Kasprian, John S. Duncan, Silvia B. Bonelli   +8 more
wiley   +1 more source

Sleep magnetoencephalography enhances detection and source imaging of seizures and fast oscillations in focal cortical dysplasia

Epilepsia, EarlyView.
Abstract Objective Focal cortical dysplasia (FCD) causes drug‐resistant epilepsy requiring presurgical evaluation. Invasive electroencephalographic (EEG) studies demonstrate that sleep modulates epileptic activity, including interictal epileptiform discharges (IEDs), fast oscillations (FOs) in the beta (14–40 Hz) and gamma (40–80 Hz) frequency bands ...
Marcel Heers, Jawata Afnan, Christoph Braun, Christophe Grova, Dirk‐Matthias Altenmüller, Bernhard J. Steinhoff, Matthias Dümpelmann, Theo Demerath, Horst Urbach, Silke Ethofer, Markus Siegel, Andreas Schulze‐Bonhage, Holger Lerche, Yiwen Li Hegner   +13 more
wiley   +1 more source

Interictal and seizure‐onset scalp electroencephalographic patterns in malformations of cortical development

Epilepsia, EarlyView.
Abstract Objective Malformations of cortical development (MCDs) are a frequent cause of drug‐resistant epilepsy and a common indication for resective epilepsy surgery. As magnetic resonance imaging (MRI) lacks sensitivity for subtle MCDs, supplemental diagnostic tools are needed.
Lubna Shakhatreh, Liz Edenberg P. Quiles, Zhibin Chen, Ofer M. Gonen, Saba Mohidat, Lyn Millist, Callum Hollis, Andrea Sundram, Piero Perucca, Terence J. O'Brien, Patrick Kwan   +10 more
wiley   +1 more source

Altered static and dynamic functional connectivity of the default mode network across epilepsy subtypes in children: A resting-state fMRI study

Neurobiology of Disease
Background: Epilepsy is a chronic neurologic disorder characterized by abnormal functioning of brain networks, making it a complex research topic. Recent advancements in neuroimaging technology offer an effective approach to unraveling the intricacies of
Yongxin Li, Yun Ran, Maohua Yao, Qian Chen   +3 more
doaj   +1 more source

Frontal Lobe Epilepsy: Bermuda's Triangle

Epilepsy Currents
Despite great progress in imaging, genetics, surgery, and therapeutics, frontal lobe epilepsy (FLE) continues to be a challenge for neurologists and epileptologists. This manuscript summarizes the latest advancements in FLE discussed at the 2023 Epilepsy Specialist Symposium during the American Epilepsy Society Annual meeting.
Mario Arturo Alonso Vanegas, Kayela Arrotta, Kathryn Davis, Barbara C. Jobst, Prakash Kotagal, Annapurna Poduri, Ignacio Valencia   +6 more
openaire   +2 more sources