The diagnostic value of semiology, EEG and MRI in new-onset pediatric bilateral tonic-clonic seizures: A multimodal analysis. [PDF]
Moussa B +7 more
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A <i>SCN1A</i> missense variant (c.4522T>A, p.(Tyr1508Asn) associated with genetic epilepsy with febrile seizures plus: clinical phenotype and genetic analysis of a Chinese pedigree. [PDF]
Li XL.
europepmc +1 more source
Postictal aggression in epilepsy: prevalence, clinical correlates, and psychosocial impact. [PDF]
Herion I +3 more
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Novel Genetic Insights into Lateral Temporal Lobe Epilepsy: Findings from Whole Exome Sequencing. [PDF]
Salman B +7 more
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Anticonvulsant drugs for generalized tonic-clonic epilepsy
Expert Opinion on Pharmacotherapy, 2017Primary generalized tonic clonic seizures (pGTCS) are still linked to major concerns for the clinic and hazards for patients suffering from idiopathic generalized epilepsy (IGE), so a quick search of the most effective and appropriate therapy is needed to control them.
Alberto Verrotti +2 more
exaly +4 more sources
The non-competitive α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) - receptor antagonist perampanel (PER) was approved in 2015 for treatment of primary generalized tonic-clonic seizures (pGTCS). The aim of this narrative review is to summarize available data on pharmacological properties, efficacy and tolerability of PER in pGTCs.Data ...
Giorgi Kuchukhidze +2 more
exaly +3 more sources
Cortical Excitability in Temporal Lobe Epilepsy with Bilateral Tonic-Clonic Seizures
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 2020ABSTRACT:Objective:We investigated motor cortical excitability (CE) in unilateral temporal lobe epilepsy (TLE) and its relationship to bilateral tonic-clonic seizure (BTCS) using paired-pulse transcranial magnetic stimulation (TMS).Methods:In this cross-sectional study, we enrolled 46 unilateral TLE patients and 16 age-and sex-matched healthy controls.
Lingli, Hu +10 more
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Generalized Tonic-Clonic Epilepsies
1987This chapter focuses on generalized tonic-clonic seizures, including both those of nonfocal origin (primarily generalized tonic-clonic seizures) and those generalized by propagation from a lateralized or restricted cortical area (secondarily generalized tonic-clonic seizures).
Bruce J. Fisch, Timothy A. Pedley
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Valproate in adolescents with photosensitive epilepsy with generalized tonic–clonic seizures only
European Journal of Paediatric Neurology, 2014To assess the effects of valproate (VPA) on seizure response/control and photosensitivity (PS) in adolescents suffering from photosensitive epilepsy with generalized tonic-clonic seizures only (EGTCS).We prospectively evaluated 55 adolescents with newly diagnosed EGTCS and PS at presentation, who received VPA monotherapy.
Verrotti, Alberto +7 more
openaire +4 more sources

