Results 111 to 120 of about 403,746 (315)
Word Adjacency Graph Modeling: Separating Signal From Noise in Big Data [PDF]
, 2016 There is a need to develop methods to analyze Big Data to inform patient-centered interventions for better health outcomes. The purpose of this study was to develop and test a method to explore Big Data to describe salient health concerns of people with ...
Groves, Doyle +4 more
core +1 more source
Combination Therapy With Vigabatrin and Prednisolone Versus Vigabatrin Alone for Infantile Spasms
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The study evaluated the effectiveness of combination therapy with vigabatrin and prednisolone versus vigabatrin alone for treating infantile epileptic spasms syndrome (IESS). Methods This single‐center, single‐blind, randomized trial enrolled infants aged 2–14 months with new‐onset IESS, randomly assigned them (1:1) to receive either
Rachata Boonkrongsak +6 more
wiley +1 more source
Epilepsia Open, 2022 SCN8A‐developmental and epileptic encephalopathy is caused by pathogenic variants in the SCN8A gene encoding the Nav1.6 sodium channel, and is characterized by intractable multivariate seizures and developmental regression.
Ángel Aledo‐Serrano +8 more
doaj +1 more source
Dissecting the genetic basis of comorbid epilepsy phenotypes in neurodevelopmental disorders. [PDF]
, 2019 BACKGROUND:Neurodevelopmental disorders (NDDs) such as autism spectrum disorder, intellectual disability, developmental disability, and epilepsy are characterized by abnormal brain development that may affect cognition, learning, behavior, and motor ...
Amini, Hajar +7 more
core
AJN, American Journal of Nursing, 1926 Idiopathic or essential epilepsy is a chronic disease of the nervous system characterized by periodically recurring convulsions, lapses or abnormal mental states occurring in persons with a personality defect or constitutional inferiority but with no demonstrated pathologic lesion. 1 It is estimated that 0.4 per cent of the population is epileptic. The
openaire +5 more sources
CSF Tau Is a Biomarker of Hippocampal Injury in Cryptogenic New‐Onset Refractory Status Epilepticus
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cryptogenic new‐onset refractory status epilepticus (cNORSE) is a devastating condition characterized by the de novo onset of status epilepticus with unclear etiology. The identification of relevant early biomarkers in cNORSE is important to elucidate pathophysiology, aid clinical decision‐making, and prognosticate outcomes in cNORSE.
Yihui Goh +8 more
wiley +1 more source
Prediction of Epilepsy Development in Traumatic Brain Injury Patients from Diffusion Weighted MRI [PDF]
arXiv, 2020 Post-traumatic epilepsy (PTE) is a life-long complication of traumatic brain injury (TBI) and is a major public health problem that has an estimated incidence that ranges from 2%-50%, depending on the severity of the TBI. Currently, the pathomechanism that in-duces epileptogenesis in TBI patients is unclear, and one of the most challenging goals in the
arxiv
Retinal nerve fibre layer thinning is associated with drug resistance in epilepsy. [PDF]
, 2015 Retinal nerve fibre layer (RNFL) thickness is related to the axonal anterior visual pathway and is considered a marker of overall white matter 'integrity'. We hypothesised that RNFL changes would occur in people with epilepsy, independently of vigabatrin
Acheson, J +11 more
core +1 more source
Neuroscience Letters, 2018 There is high variability in the response to antiepileptic treatment across people with epilepsy. Genetic factors significantly contribute to such variability. Recent advances in the genetics and neurobiology of the epilepsies are establishing the basis for a new era in the treatment of epilepsy, focused on each individual and their specific epilepsy ...
Balestrini S, Sisodiya SM
openaire +4 more sources
Advanced Functional Materials, EarlyView.Ultrathin, flexible neural probes are developed with an innovative, biomimetic design incorporating brain tissue‐compatible materials. The material system employs biomolecule‐based encapsulation agents to mitigate inflammatory responses, as demonstrated through comprehensive in vitro and in vivo studies.
Jeonghwa Jeong +7 more
wiley +1 more source