Results 241 to 250 of about 403,746 (315)

Targeting signaling pathways in neurodegenerative diseases: Quercetin's cellular and molecular mechanisms for neuroprotection

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Quercetin regulates signaling pathways in neurodegenerative diseases, including NF‐κB, sirtuins, and PI3K/Akt. Studies show quercetin improves symptoms and pathology in neurodegenerative models. The study aims to incorporate laboratory research into practical medical treatment, focusing on quercetin's neuroprotective effects and optimal dosage ...
Md. Rezaul Islam   +13 more
wiley   +1 more source

Low-dose fenfluramine as an effective treatment option for ‘atypical’ Dravet syndrome

open access: yesEpilepsy & Behavior Reports
Dravet syndrome (DS) is characterized by recurrent convulsive seizures, including status epilepticus, and intellectual disability as a comorbidity. Seizures associated with DS are commonly resistant to antiseizure medications.
Akihiro Iguchi   +7 more
doaj  

Use of laryngeal muscle evoked potential recording for experimental vagus nerve stimulation

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Laryngeal muscle evoked potentials (LMEPs) reflect the activation of laryngeal muscles induced by vagus nerve stimulation (VNS) via vagal Aα‐motor fibers. LMEP recordings are minimally invasive and provide a feasible, reliable method for assessing the integrity of the electrode‐nerve interface during experimental VNS in rodents.
Helen Bachmann   +3 more
wiley   +1 more source

FEIGNED EPILEPSY [PDF]

open access: green, 1880
Carlos F. Mac Donald
openalex   +1 more source

Identifying the optimal dose of cannabidiol by intrabuccal administration in Kramnik (C3HeB/FeJ) mice

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Cannabidiol (CBD) has numerous therapeutic properties, and is used to treat neurological conditions, such as neuroinflammation. However, the optimal dose of CBD to penetrate the brain requires further investigation. The primary aim of this study was to use a mouse model and the intrabuccal route for CBD administration to determine the optimal dose at ...
Oluwadara Pelumi Omotayo   +4 more
wiley   +1 more source

Diagnosing Epilepsy with Normal Interictal EEG Using Dynamic Network Models

open access: yesAnnals of Neurology, EarlyView.
Objective Whereas a scalp electroencephalogram (EEG) is important for diagnosing epilepsy, a single routine EEG is limited in its diagnostic value. Only a small percentage of routine EEGs show interictal epileptiform discharges (IEDs) and overall misdiagnosis rates of epilepsy are 20% to 30%.
Patrick Myers   +18 more
wiley   +1 more source

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