Results 261 to 270 of about 403,746 (315)
Annals of Neurology, EarlyView.Objective Genetic dystonia is a complex movement disorder with diverse clinical manifestations resulting from pathogenic mutations in associated genes. A recent paradigm shift emphasizes the functional convergence among dystonia genes, hinting at a shared pathomechanism. However, the neural dynamics supporting this convergence remain largely unexplored.
Ahmet Kaymak +18 more
wiley +1 more source
Neuroimaging Predictors of Cognitive Resilience against Alzheimer's Disease Pathology
Annals of Neurology, EarlyView.Objective Some individuals demonstrate greater cognitive resilience—the ability to maintain cognitive performance despite adverse brain‐related changes—through as yet unknown mechanisms. We examined whether cortical thickness in several brain regions confers resilience against cognitive decline in amyloid‐positive adults by moderating the effects of ...
McKenna E. Williams +7 more
wiley +1 more source
Annals of Neurology, EarlyView.Objectives Intravenous thrombolysis (IVT) is contraindicated for acute ischemic stroke (AIS) patients taking direct oral anticoagulants (DOACs) within 48 hours before index stroke. Limited data exist on off‐label use of IVT for these patients. We compared the safety and outcomes of IVT in AIS patients with DOAC treatment and patients with no OAC before
Marius Matusevicius +11 more
wiley +1 more source
Annals of Neurology, EarlyView.Objective Despite diagnostic criteria refinements, Parkinson's disease (PD) clinical diagnosis still suffers from a not satisfying accuracy, with the post‐mortem examination as the gold standard for diagnosis. Seminal clinicopathological series highlighted that a relevant number of patients alive‐diagnosed with idiopathic PD have an alternative post ...
Lazzaro di Biase +2 more
wiley +1 more source
Annals of Neurology, EarlyView.Objective We aimed to evaluate the diagnostic accuracy of heparin‐binding protein (HBP) in cerebrospinal fluid for the diagnosis of bacterial meningitis in patients with a suspected central nervous system infection. Methods This prospective multicenter cohort study determined the diagnostic accuracy of HBP in cerebrospinal fluid (CSF) for bacterial ...
Sabine E. Olie +6 more
wiley +1 more source
Annals of Neurology, EarlyView.Objective The objective is to evaluate cognitive and behavioral progression and identify early predictors of these changes in a cohort of amyotrophic lateral sclerosis (ALS) patients. Methods A total of 161 ALS patients were tested at diagnosis (T0), and 107 were re‐tested after 1 year (T1) using cognitive/behavioral tests. All patients underwent whole‐
Barbara Iazzolino +13 more
wiley +1 more source
Accelerated Cellular Senescence in Progressive Multiple Sclerosis: A Histopathological Study
Annals of Neurology, EarlyView.Objective The neurodegenerative processes driving the build‐up of disability in progressive multiple sclerosis (P‐MS) have not been fully elucidated. Recent data link cellular senescence (CS) to neurodegeneration. We investigated for evidence of CS in P‐MS and sought to determine its pattern.
Dimitrios Papadopoulos +8 more
wiley +1 more source
IEE Seminar on Electrical Engineering and Epilepsy: A Successful Partnership in conjunction with the Epilepsy Research Foundation, 1998 openaire +4 more sources