Results 271 to 280 of about 730,852 (352)

From Diagnosis to Disease Staging: Multisite Validation of Cerebrospinal Fluid Molecular Tests in Multiple Sclerosis

Annals of Neurology, EarlyView.
Objective The growing demand for personalized treatment in multiple sclerosis (MS) highlights the need for more precise biomarkers that can outperform magnetic resonance imaging and clinical assessment in patient stratification. Advances in multiplex proteomic technologies suggest that cerebrospinal fluid (CSF) analysis at MS onset may not only improve
Laura Ghezzi, Peter Kosa, Mark Greenwood, Enrique Alvarez, C.L. Freedman, Anne H. Cross, Francesca Pace, Mark S. Freedman, Joanna Kocot, Laura Piccio, Bibiana Bielekova   +10 more
wiley   +1 more source

Efficacy and safety of levetiracetam treatment in childhood epilepsy

Arife Toksoz, Serap Teber
openalex   +2 more sources

Editorial: Sudden Unexpected Death in Epilepsy: Bio-markers, Mechanisms, Risk Identification and Prevention. [PDF]

, 2019
DeGiorgio, Christopher M., Sperling, Michael R., Surges, Rainer   +2 more
core   +1 more source

Recombinant Human Neuregulin1‐β1 Significantly Reduces Schwannoma Growth in Mice

Annals of Neurology, EarlyView.
rhNRGβ1‐Replacement‐Therapy: Under physiological conditions, NRGβ1 is expressed on axons (in orange), where it activates ERBB2 receptors, facilitating successful nerve regeneration following injury. However, loss of NF2 leads to a reduction in NRGβ1‐expression and increased ErbB2 levels on Schwann cells (in green), which contributes to schwannoma ...
Julia P. Bischoff, Alexander Schulz, Christian Hagel, Robert Büttner, Michael Reuter, Waylan K. Bessler, D. Wade Clapp, Helen Morrison   +7 more
wiley   +1 more source

Whole Exome Sequencing in Patients With Developmental Delay/Intellectual Disability (DD/ID), Epilepsy and the First Turkish Patient Diagnosed With BCL11A-Related Intellectual Disability. [PDF]

Mol Genet Genomic Med
Akkus N, Canbal A, Guneysu S, Gokce E, Duzgun P, Barıs İ.   +5 more
europepmc   +1 more source

Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies [PDF]

, 2018
Thio, Liu Lin, Weisenberg, Judith
core   +1 more source

Combination of Serum Neurofilament Light Chain and Serum Cardiac Troponin T as Biomarkers Improves Diagnostic Accuracy in Amyotrophic Lateral Sclerosis

Annals of Neurology, EarlyView.
Objective We aimed to evaluate the clinical utility of serum neurofilament light chain (sNfL) and cardiac troponin T (cTnT) in amyotrophic lateral sclerosis (ALS) and assess whether their combination improves diagnostic accuracy. Methods We retrospectively analyzed 293 ALS patients, 85 neurodegenerative disease controls, and 29 healthy controls.
Paula Lindenborn, Rachel Fabian, Torsten Grehl, Huelya Nazlican, Thomas Meyer, Sarah Bernsen, Patrick Weydt   +6 more
wiley   +1 more source

Exploratory analysis of epilepsy biomarkers using untargeted metabolomics across multiple cohorts. [PDF]

Front Neurol
Oja KT, Ilisson M, Reinson K, Muru K, Reimand T, Peterson H, Fishman D, Haller T, Kronberg J, Estonian Biobank Research Team, Wojcik MH, Kennedy AD, Sommerville L, Michelotti G, O'Donnell-Luria A, Õiglane-Shlik E, Pajusalu S, Õunap K.   +17 more
europepmc   +1 more source

Epilepsy mortality trends in Brazil (2001-2022): a joinpoint analysis

Emmanuel Santos Trindade, Gustavo Alves Cangussú, Priscila Santos Oliveira, ÉMILE DE CARVALHO MORAIS FRAGA, Maria Fernanda Aragão Andrade, Davi Tanajura Costa, Philip George Glass Andrade   +6 more
openalex   +1 more source

Disruption of the Blood–Brain Barrier Predicts Progression of Cerebral Small Vessel Disease White Matter Hyperintensities

Annals of Neurology, EarlyView.
Objective The objective of this study was to test if blood–brain barrier (BBB) disruption, detected using dynamic susceptibility contrast (DSC) imaging, would predict progression of white matter hyperintensities (WMHs) over the subsequent year in patients with chronic cerebrovascular disease. Methods The study included patients with a history of stroke
Richard Leigh, Kyle C. Kern, Nae‐Yuh Wang, Rebecca F. Gottesman, Clinton B. Wright   +4 more
wiley   +1 more source