Results 21 to 30 of about 276,627 (258)

Epilepsy [PDF]

Current Biology, 2015
Our cognitive abilities emerge from the coordinated activity of neurons in the brain. The average human brain contains 86 billion neurons that are richly interconnected through synapses, contact points for electrochemical communication. Patterns of synaptic connectivity create functional ensembles of neurons, called neural circuits, which mediate ...
Rao, Vikram R., Lowenstein, Daniel H.
openaire   +2 more sources

Perceived epilepsy-related stigma is linked to the socioeconomic status of the residence

Frontiers in Public Health, 2022
PurposeEpilepsy is one of the most common neurological disorders with high costs for the healthcare systems and great suffering for patients. Beyond seizures, psychosocial comorbidities can have detrimental effects on the well-being of people with ...
Louisa Hohmann, Louisa Hohmann, Justus Berger, Shirley-Uloma Kastell, Martin Holtkamp, Martin Holtkamp   +5 more
doaj   +1 more source

Naming fMRI predicts the effect of temporal lobe resection on language decline

Annals of Clinical and Translational Neurology, 2019
Objective To develop language functional MRI (fMRI) methods that accurately predict postsurgical naming decline in temporal lobe epilepsy (TLE). Methods Forty‐six patients with TLE (25 left) and 19 controls underwent two overt fMRI paradigms (auditory ...
Karin Trimmel, Louis A. vanGraan, Gloria G. Gonzálvez, Anja Haag, Lorenzo Caciagli, Sjoerd B. Vos, Silvia Bonelli, Meneka Sidhu, Pamela J. Thompson, Matthias J. Koepp, John S. Duncan   +10 more
doaj   +1 more source

Limitations of a Short Demographic Questionnaire for Bedside Estimation of Patients’ Global Cognitive Functioning in Epilepsy Patients

Frontiers in Neurology, 2018
ObjectivesThe German socio-demographic estimation scale was developed by Jahn et al. (1) to quickly predict premorbid global cognitive functioning in patients. So far, it has been validated in healthy adults and has shown a good correlation with the full
Iris Gorny, Kristina Krause, Anita Albert, Sabrina Schneider, Leona Möller, Lena Habermehl, Adam Strzelczyk, Adam Strzelczyk, Felix Rosenow, Felix Rosenow, Anke Hermsen, Anke Hermsen, Susanne Knake, Katja Menzler   +13 more
doaj   +1 more source

Development and Validation of CRISPR Activator Systems for Overexpression of CB1 Receptors in Neurons

Frontiers in Molecular Neuroscience, 2020
Gene therapy approaches using viral vectors for the overexpression of target genes have been for several years the focus of gene therapy research against neurological disorders.
Valentina Di Maria, Marine Moindrot, Martin Ryde, Antonino Bono, Luis Quintino, Marco Ledri   +5 more
doaj   +1 more source

RLAE

Эпилепсия и пароксизмальные состояния, 2020
Decision of the All-Russian Society of Neurologists Presidium 23.12.2019;Russian League Against Epilepsy.
Russian League Against Epilepsy
doaj  

Genetic generalized epilepsies with frontal lesions mimicking migratory disorders on the epilepsy monitoring unit

Epilepsia Open, 2020
Objective Some patients with genetic generalized epilepsy (GGE) may present with ambiguous and atypical findings and even focal brain abnormalities. Correct diagnosis may therefore be difficult.
Susanne Fauser, Thomas Cloppenborg, Tilman Polster, Ulrich Specht, Friedrich G. Woermann, Christian G. Bien   +5 more
doaj   +1 more source

Development and Implementation of a Disease‐Targeted Storybook as a Clinical Tool for Children With Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Although significant progress has been made in childhood leukemia survival, healthcare providers, and caregivers often face challenges in explaining this disease to patients. Disease‐targeted storybooks have been proposed as a tool to facilitate the understanding of diagnoses and treatment.
Nutvipha Ummartyotin, Usanarat Anurathapan, Rawiwan Roongpraiwan, Potchanee Dandamrongrak, Siriporn Nakhonchai, Pawin Numthavaj, Vilawan Chirdkiatgumchai   +6 more
wiley   +1 more source

First-year Experience with Brivaracetam in Japan: Real-world Data from Juntendo Epilepsy Center

Neurologia Medico-Chirurgica
Approximately 30% of patients still develop drug-resistant epilepsy despite the introduction of newer antiseizure medications. Brivaracetam, a high-affinity synaptic vesicle protein 2A ligand with a mechanism of action similar to that of levetiracetam ...
Yasushi IIMURA, Kazuki NOMURA, Takumi MITSUHASHI, Hiroharu SUZUKI, Tetsuya UEDA, Kazuki NISHIOKA, Taiji TSUNEMI, Shinichi UENO, Hidenori SUGANO, Akihide KONDO   +9 more
doaj   +1 more source

Surgical treatment of pediatric intractable frontal lobe epilepsy due to malformation of cortical development

Acta Epileptologica, 2022
Background Malformation of cortical development (MCD) is a common cause of intractable epilepsy in children. In this study, the effectiveness of frontal lobe epilepsy (FLE) surgery in children with intractable epilepsy due to MCD was assessed and its ...
Hao Yu, Qiang Lv, Qingzhu Liu, Shuang Wang, Taoyun Ji, Ruofan Wang, Wen Wang, Dongming Wang, Yuwu Jiang, Xiaoyan Liu, Lixin Cai   +10 more
doaj   +1 more source