Results 331 to 340 of about 939,161 (398)

Targeted Proteomics upon Treatment with Tofersen Identifies Novel Response Markers for Superoxide Dismutase 1‐Linked Amyotrophic Lateral Sclerosis

Annals of Neurology, EarlyView.
Objective Tofersen is the first effective and approved therapy for superoxide dismutase 1 (SOD1)‐associated amyotrophic lateral sclerosis (ALS [SOD1‐ALS]). Following treatment with tofersen, neurofilament levels in patients' cerebrospinal fluid (CSF) and serum seem to respond earlier than clinical parameters.
Christina Steffke, Karthik Baskar, Franziska Bachhuber, Maximilian Wiesenfarth, Johannes Dorst, Joachim Schuster, Florian Schöberl, Peter Reilich, Martin Regensburger, Alexander German, René Günther, Maximilian Vidovic, Susanne Petri, Thomas Meyer, Tim Hagenacker, Julian Grosskreutz, Ute Weyen, Patrick Weydt, Thomas Haarmeier, Paul Lingor, Joachim Wolf, Andreas Hermann, Johannes Prudlo, Kornelia Günther, Antje Knehr, Zeynep Elmas, Zeljko Uzelac, Simon Witzel, Wolfgang Philipp Ruf, Axel Freischmidt, Ritchie Ho, Albert C. Ludolph, Jochen H. Weishaupt, Hayrettin Tumani, Patrick Oeckl, David Brenner, Alberto Catanese   +36 more
wiley   +1 more source

Thalamocortical hodology to personalize electrical stimulation for focal epilepsy. [PDF]

Nat Commun
Damiani A, Nouduri S, Ho JC, Salazar S, Jegou A, Chen JJ, Reedy E, Ikegaya N, Sarma S, Aung T, Pirondini E, Gonzalez-Martinez JA.   +11 more
europepmc   +1 more source

Disease Progression in Multiple System Atrophy: The ASPIRE Multi‐Modal Biomarker Study

Annals of Neurology, EarlyView.
Objective The objective of this study was to characterize changes in candidate biomarkers in early multiple system atrophy (MSA) and identify baseline predictors of faster progression. Methods This 1‐year, multicenter, prospective study assessed clinical, neuroimaging (3T‐magnetic resonance imaging [MRI], dopamine transporter single‐photon emission ...
Margherita Fabbri, Natalia del Campo, Wassilios G. Meissner, Vanessa Rousseau, Agnès Sommet, Pierre Payoux, Pierre Gantet, Amel Drif, Hélène Catalá, Claire Thalamas, Christine Tranchant, Franck Durif, Ana Marques, Alexandre Eusebio, Luc Defebvre, Jean‐Christophe Corvol, Stéphane Thobois, Anthime Flaus, Anne‐Gaelle Corbille, Solène Frismand, Beverley Patterson, Alexandra Foubert‐Samier, Anne Pavy‐Le Traon, Germain Arribarat, Patrice Péran, Olivier Rascol, for the ASPIRE Study Group   +26 more
wiley   +1 more source

Exploring the causal effects of epilepsy and its subtypes on anthropometric traits: A 2-sample Mendelian randomization study. [PDF]

Medicine (Baltimore)
Chen L, Hu X, Wu M, Zeng Z, Wang Y.
europepmc   +1 more source

Intranasal Wharton's Jelly‐Derived Mesenchymal Stem Cell Therapy, Alone or in Conjunction With Therapeutic Hypothermia, Alleviates Neonatal Hypoxic‐Ischemic Brain Injury in Mice

Annals of Neurology, EarlyView.
This study demonstrates that intranasal Wharton's jelly‐derived mesenchymal stem cell (WJ‐MSC) administration at 3 or 10 days post‐insult reduced the lesion size and sensorimotor impairment following neonatal hypoxic‐ischemic (HI) brain injury in mice. WJ‐MSCs expressed receptors for HI‐upregulated chemokines and migrated from the nasal cavity into the
Caroline G. M. de Theije, Sara T. De Palma, Josine E. G. Vaes, Katiuscia Dallaglio, Giorgia Volpi, Diego Ardigò, Sabine van Rijt, Frank van Bel, Manon J. N. L. Benders, Cora H. A. Nijboer   +9 more
wiley   +1 more source

EEG microstates, spectral analysis, and risk prediction in epilepsy comorbid with mild cognitive impairment: alteration in intrinsic brain activity. [PDF]

J Transl Med
Fang S, Chen S, Chen L, Lin H, Liu C, Che C, Xiong W, Zhang Y, Li J, Wu L, Huang X, Huang H, Lin W, Zhu C.   +13 more
europepmc   +1 more source

Extended Analysis of Status Epilepticus and Cluster Seizures in Dogs in the Context of Overall Epilepsy Incidence: 254 Cases. [PDF]

Animals (Basel)
Jankauskas M, Gradeckienė A, Čižinauskas S, Saalasti O, Kvitka D, Riškevičienė V.   +5 more
europepmc   +1 more source

PET imaging pitfall in recurrent oligodendroglioma with drug-resistant epilepsy: illustrative case. [PDF]

J Neurosurg Case Lessons
Niedermeyer S, Schmutzer-Sondergeld M, Kirchleitner SV, Quach S, Albert NL, Thon N.   +5 more
europepmc   +1 more source

Epilepsy in women of childbearing age: a focused review. [PDF]

Neurol Res Pract
Heckelmann J, Schmitz B, Weber YG, Mann C.   +3 more
europepmc   +1 more source

Decoding the relationship between oxidative stress and antiseizure medications using network pharmacology and molecular docking. [PDF]

Sci Rep
Desai M, Singh SD, Nagamani S, Malik S, Singh A, Kukreti R, Kukreti S, Grewal GK.   +7 more
europepmc   +1 more source