Results 211 to 220 of about 2,852,642 (351)

Preclinical signal for a disease‐modifying effect on seizure cluster severity with intermittent diazepam treatment

Epilepsia, EarlyView.
Abstract Objective In epilepsy, daily treatment provides only symptomatic seizure control, leaving a significant unmet need for a treatment that affects the underlying predisposition to seizures. Here, in a first‐of‐its‐kind study, we test the hypothesis that intermittent treatment of seizure clusters with diazepam in the kainic acid post‐status ...
Qian Wu, Michelle Guignet, Jonathan Vuong, H. Steve White, Wesley T. Kerr, Evelyn K. Shih, Leock Y. Ngo, Enrique Carrazana, Adrian L. Rabinowicz   +8 more
wiley   +1 more source

A systematic survey of the measures used to identify postoperative changes in language function following epilepsy surgery. [PDF]

Epilepsia Open
Puntambekar I, Koepp M, Xiao F, Baxendale S.   +3 more
europepmc   +1 more source

Connectivity between the seizure onset zone and the thalamus correlates with seizure outcomes in thalamic responsive neurostimulation

Epilepsia, EarlyView.
Abstract Objective Thalamic responsive neurostimulation (RNS) is a surgical option for patients with drug‐refractory epilepsy. However, it is unclear whether thalamic connectivity with the seizure onset zone (SOZ) has a role in clinical outcomes. Here, we aim to investigate the clinical utility of the connectivity between the SOZ and the thalamus for ...
Varun R. Subramaniam, Andy Ho Wing Chan, Lara Marcuse, Madeleine Fields, Maite La Vega‐Talbott, Daniel D. Cummins, Juan A. Barcia, Hesham T. Ghonim, Lakshman Arcot Jayagopal, Yunju Im, Saadi Ghatan, Fedor Panov, Josue M. Avecillas‐Chasin   +12 more
wiley   +1 more source

Long-term survival after adult epilepsy surgery: Mortality and predictors in a large cohort. [PDF]

Epilepsia
Fiore G, de Tisi J, O'Keeffe A, Miserocchi A, McEvoy AW, Sander JW, Duncan JS.   +6 more
europepmc   +1 more source

Conscious sedation for epilepsy surgery [PDF]

, 2014
Don Jose Palamattam, Dilip Kulkarni, Gopinath Ramachandran   +2 more
openalex   +1 more source

Cardiorespiratory cross‐frequency coupling biomarker for sudden unexpected death in epilepsy

Epilepsia, EarlyView.
Abstract Objective Sudden unexpected death in epilepsy (SUDEP) often follows generalized tonic–clonic seizures during sleep, likely resulting from impaired brainstem cardiorespiratory function. We used ictal electrocardiogram (ECG)‐based cross‐frequency phase–amplitude coupling (PAC) to detect cardiorespiratory disruptions, comparing SUDEP to non‐SUDEP
Adam C. Gravitis, Richard Wennberg, Peter L. Carlen, Yotin Chinvarun, Victor Lira, Juliana Laze, Orrin Devinsky, Berj L. Bardakjian   +7 more
wiley   +1 more source

Trends in epilepsy surgery in Italy before and after the COVID-19 pandemic: A nationwide study. [PDF]

Epilepsia
Didato G, Vigevano F, Tassi L, Guerrini R, de Curtis M, De Palma L, Di Gennaro G, Nobili L, Martinoni M, Meletti S, Battaglia D, Cesaroni E, Vittorini R, Grisotto L, d'Orsi G, Dilena R, Pingue V, Nardone A, Ranzato F, Zucca C, Bonanni P, Mattioli P, Tamburrini G, Quintiliani M, Luzi M, Trignani R, Torta F, Morana G, Pugnaghi M, Vaudano AE, Bisulli F, Pasini E, Consales A, Nobile G, Esposito V, Quarato PP, Freri E, Marras CE, Giordano F, Pelliccia V, Castana L, Specchio N, Costantino U, Pluderi M, Rizzi M, Polo D, Zambrano S, Danieli A, Villani F, Barba C, Italian Epilepsy Surgery Collaborative Group.   +50 more
europepmc   +1 more source

A call for ethical, equitable, and effective artificial intelligence to improve care for all people with epilepsy: A roadmap. A report by the ILAE Global Advocacy Council and Big Data Commission

Epilepsia, EarlyView.
Abstract The artificial intelligence (AI) revolution is upon us. It will inevitably form a central component of epilepsy workflows and patient advocacy. Therefore, it behooves us as health care providers to ride the crest of this wave and guide its direction for the benefit of all people with epilepsy.
Colin B. Josephson, Sandor Beniczky, Spiros Denaxas, Akio Ikeda, Lara Jehi, Angelina Kakooza Mwesige, Nathalie Jette, Gabriel Davis Jones, Philippe Ryvlin, Arjune Sen, Chahnez Charfi Triki, Gabriella Waters, Alla Guekht, J. Helen Cross   +13 more
wiley   +1 more source

The landscape of epilepsy surgery in older adults: Challenges and opportunities. [PDF]

Epilepsia Open
Punia V.
europepmc   +1 more source

Synchrotron‐generated microbeams as a radiosurgical alternative for drug‐resistant epilepsies: Proof of concept in a mouse model of mesiotemporal lobe epilepsy

Epilepsia, EarlyView.
Abstract Objective One‐third of patients with epilepsy, particularly those with mesial temporal lobe epilepsy (MTLE), remain resistant to medication. Resective surgery, the gold standard, is highly invasive and carries significant risks. Here, using a mouse model, we explored the potential of microbeam radiation therapy (MRT), a new technique based on ...
Loan Samalens, Camille Beets, Clothilde Courivaud, Sarvenaz Keshmiri, Jean‐François Adam, Paolo Pellicioli, Emmanuel Luc Barbier, Raphaël Serduc, Antoine Depaulis   +8 more
wiley   +1 more source