Results 231 to 240 of about 8,695 (262)

Analysis of surgical strategies for children with epileptic spasms

Epileptic Disorders, 2021
AbstractObjective: To investigate surgical prognostic factors in order to establish a surgical plan for children with drug‐resistant epileptic spasms.Methods: We retrospectively analysed 64 children with drug‐resistant spasms who were operated on in Beijing; the electroclinical features, surgical procedures, and surgical outcomes of these children were
Yiou, Liu, Wenjing, Zhou, Bo, Hong, Haixiang, Wang, Jiuluan, Lin, Zhaohui, Sun, Siyu, Wang   +6 more
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Evolution of Surgical Management for Intractable Epileptic Spasms

Seminars in Pediatric Neurology, 2020
The understanding and management of epileptic spasms has considerably evolved since the mid 19th century. The realization that epileptic spasms can be generated from a focal brain lesion played a pivotal role in the development of neurosurgical management for intractable forms of this epilepsy.
Salman, Rashid, Harry T, Chugani
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Adjunctive perampanel therapy for patients with epileptic spasms

Pediatrics International, 2022
AbstractBackgroundPerampanel is an antiepileptic drug. Some studies have documented the efficacy of perampanel in epileptic spasms. We aimed to evaluate the efficacy and safety of adjunctive perampanel therapy (PT) in patients with epileptic spasms.MethodsWe retrospectively surveyed the efficacy and safety of adjunctive PT in 14 patients with epileptic
Ryuki Matsuura, Shin‐ichiro Hamano, Satoru Ikemoto, Atsuro Daida, Rikako Takeda, Ayumi Horiguchi, Yuko Hirata, Reiko Koichihara, Kenjiro Kikuchi   +8 more
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Status of epileptic spasms: A study of 21 children

Epilepsy & Behavior, 2022
We studied cases with long-lasting epileptic spasms (ES) considered as a spasm status analyzing type of epilepsy, epileptic syndrome, etiology, treatment, and outcome in 21 patients.We evaluated the charts of 21 patients seen between June 2006 and July 2017 who met the electroclinical diagnostic criteria of a spasm status.
Roberto, Caraballo, Marcos, Semprino, Lorena, Fasulo, Gabriela, Reyes, Santiago, Chacón, Adolfo, Gallo, Celeste, Buompadre   +6 more
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Epileptic Spasms in a Large Hypothalamic Hamartoma Cohort

Journal of Child Neurology, 2020
Introduction: Hypothalamic hamartoma is rarely associated with epileptic spasms. We describe epileptic spasms in a large cohort of hypothalamic hamartoma patients. Methods: We performed a retrospective chart review between March 2011 ...
Cemal Karakas, Angus A. Wilfong, James J. Riviello, Daniel J. Curry, Irfan Ali   +4 more
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Genetics of infantile epileptic spasms syndrome in China

Developmental Medicine & Child Neurology
Abstract Aim To construct a genetic landscape of infantile epileptic spasms syndrome (IESS) and explore the pathogenic mechanisms of IESS‐associated genes. Method We conducted a nationwide, multicentre, retrospective ...
Zhao Xu, Zongpu Zhou, Genfu Zhang, Jiaxin Zhuang, Yufen Li, Shuang Wang, Siqi Hong, Dan Sun, Jiong Qin, Zhixian Yang   +9 more
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Epileptic Spasms: A Variety of Etiologies and Associated Syndromes

Journal of Child Neurology, 2008
Epileptic spasms have been described as a paroxysmal epileptic seizure type that consists of a series of motor movements, involving sudden flexion or extension predominantly of axial and/or proximal limb muscles, occurring with a noticeable periodicity, outside the age of infantile spasms, but have otherwise not been well characterized or described ...
Joshua, Goldstein, Jessica, Slomski
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Infantile epileptic spasms syndrome: When spasms come out of the blue

Epilepsy & Behavior
This study evaluates the electroclinical features of infantile epileptic spasms syndrome (IESS) suddenly appearing in previously normal patients, aiming to describe clinical outcomes and independent predictors.We retrospectively selected a homogeneous group of patients with IESS from two Italian centers.
Conti M, Matricardi S, Piscitello LM, Auconi M, Cursio I, Terracciano A, Vigevano F, Specchio N, Marini C, Fusco L.   +9 more
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[Benign epileptic infantile spasms].

Revue d'electroencephalographie et de neurophysiologie clinique, 1987
Among 100 infants with infantile spasms studied before treatment, 14 had idiopathic spasms with a favourable outcome. They had a normal development, including reaching for objects before the age of 5 months and moderate regression without loss of eye following.
O, Dulac, P, Plouin, I, Jambaque, J, Motte   +3 more
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Whole Genome Sequencing in Developmental Epileptic Encephalopathy with Epileptic Spasms and Infantile Epileptic Spasms Syndrome with Unknown Etiology

Objective: This study aimed to evaluate the diagnostic yield of whole genome sequencing (WGS) in patients with developmental epileptic encephalopathy manifesting with epileptic spasms (DEE-ES) and infantile epileptic spasms syndrome (IESS) with unknown etiology, and to assess treatment outcomes of patients with and without a genetic diagnosis.Methods ...
Kullasate Sakpichaisakul, Rachata Boonkrongsak, Kantapon Trongkamolchai, Sirorat Suwannachote, Somjit Sri-udomkajorn, Navarat Rungteeranon, Chaiyos Khongkhatithum, Chanikhan Sattaporn, Thitiporn Fangsaad, Nareenart Iemwimangsa, Sommon Klumsathian, Bhakbhoom Panthan, Objoon Trachoo   +12 more
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