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Infantile epileptic spasms syndrome in a child with lissencephaly associated with de novo PAFAH1B1 variant and coincidental CMV infection. [PDF]
Ying Eng N, Nie DA.
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Three different scenarios for epileptic spasms
Epilepsy & Behavior, 2020Epileptic Spasms (ES) is a type of seizure usually occurring in the context of a severe childhood epileptic syndrome associated to significant Electroencephalogram (EEG) abnormalities. There are three scenarios in which ES may occur. The first one is represented by West Syndrome (WS): ES occur in a previously non encephalopathic infant in association ...
Lucia Fusco +2 more
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Epileptic spasms in tuberous sclerosis complex
Epilepsy Research, 2013To characterize epileptic spasms (ES) occurring after the age of two years in patients with tuberous sclerosis complex (TSC), particularly treatment response to vigabatrin (VGB), which is extremely effective for infantile spasms (IS) in TSC.The authors retrospectively reviewed 19 patients with TSC and ES.
David T, Hsieh +2 more
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Cingulate Lesions Presenting With Epileptic Spasms
Journal of Clinical Neurophysiology, 2009To describe the novel finding of epileptic spasms arising from a cingulate lesion.We describe two children presenting with epileptic spasms who had lesions of the cingulate gyrus on MRI.In both patients, the lesions involved the midcingulate cortex. Seizures were characterized by prominent motor manifestations and resembled spasms.
Dewi, Schrader +4 more
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Extent of EEG monitoring for detecting epileptic spasms
Seizure, 2022Epileptic spasms (ES) are the ictal manifestation of West syndrome. Due to poor interrater reliability in diagnosing hypsarrhythmia, identification of ES - ideally on video EEG monitoring - is important to start proper treatment.We retrospectively analyzed inpatient video EEG recordings of 42 patients with new onset ES and calculated the time needed to
Akshat Katyayan +3 more
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Rufinamide for the treatment of epileptic spasms
Epilepsy & Behavior, 2011The purpose of this study was to determine the safety and efficacy of rufinamide for treatment of epileptic spasms.We retrospectively reviewed patients treated with rufinamide for epileptic spasms from January 2009 to March 2010. Age, presence of hypsarrhythmia, change in seizure frequency following rufinamide initiation, and side effects were assessed.
H E, Olson +11 more
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Adjunctive perampanel therapy for patients with epileptic spasms
Pediatrics International, 2022AbstractBackgroundPerampanel is an antiepileptic drug. Some studies have documented the efficacy of perampanel in epileptic spasms. We aimed to evaluate the efficacy and safety of adjunctive perampanel therapy (PT) in patients with epileptic spasms.MethodsWe retrospectively surveyed the efficacy and safety of adjunctive PT in 14 patients with epileptic
Ryuki Matsuura +8 more
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Clinical spectrum of epileptic spasms in children
Brain and Development, 2015To compare etiologic, semiologic, and electrographic features of epileptic spasms (ES) in children with West syndrome (WS) vs. in children with other epilepsy syndromes and nonsyndromic epilepsies.The 24h-video/EEG recordings of consecutive children with ES were reviewed for etiology, ictal semiology, and interictal and ictal EEG features.
Yun-Jin Lee +2 more
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Atonic elements combined or uncombined with epileptic spasms in infantile spasms
Clinical Neurophysiology, 2017To study the atonic elements combined or uncombined with epileptic spasms in infantile spasms.The demographic data, clinical characteristics, electroencephalogram (EEG), and polyelectromyography (PEMG) features were analyzed in 12 infantile spasm patients with atonic elements.A total of 29 EEGs were recorded.
Jiao, Xue +6 more
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