Results 101 to 110 of about 41,822 (309)

Exploring the role of apolipoprotein ε4 in progressive myoclonic epilepsy type 1

Epileptic Disorders, EarlyView.
Abstract Objective Progressive myoclonic epilepsy type 1 (EPM1) is a neurodegenerative disease caused by biallelic variants in the cystatin B (CSTB) gene. Despite a progressive course, phenotype severity varies among patients, even within families. We studied the potential role of APOE ε4 in modifying phenotypic diversity in EPM1, given its established
Janina Gunnar, Yawu Liu, Henri Eronen, Tarja Joensuu, Marja Äikiä, Jelena Hyppönen, Katri Silvennoinen, Esa Mervaala, Juhana Hakumäki, Anna‐Elina Lehesjoki, Reetta Kälviäinen   +10 more
wiley   +1 more source

Transient and selective blockade of adenosine A1-receptors by 8-cyclopentyl-1,3-dipropylxanthine (DPCPX) causes sustained epileptiform activity in hippocampal CA3 neurons of guinea pigs [PDF]

, 1989
The effects of endogenously released adenosine on the excitability of hippocampal neurons were studied using the novel and highly selective adenosine A1-receptor antagonist 8-cyclopentyl-1,3-dipropylxanthine (DPCPX).
Alzheimer, Christian, Sutor, Bernd, Ten Bruggencate, Gerrit   +2 more
core   +1 more source

Efficacy of vagus nerve stimulator during transition to adulthood in patients with treatment‐resistant epilepsy

Epileptic Disorders, EarlyView.
Abstract Objective To evaluate the efficacy of vagus nerve stimulation (VNS) as an adjunctive treatment in pediatric patients with treatment‐resistant epilepsy during the transition to adolescence. Methods We performed a retrospective cohort study of 30 children (ages 2–18 years) with medication‐resistant epilepsy who underwent VNS implantation between
Jonadab dos Santos Silva, Shaylla Villas Boas, Henrique Januzzelli Pires do Prado, Daniela Fontes Bezerra, Isabella D’Andrea Meira   +4 more
wiley   +1 more source

EEG–fMRI mapping of asymmetrical delta activity in a patient with refractory epilepsy is concordant with the epileptogenic region determined by intracranial EEG [PDF]

, 2006
We studied a patient with refractory focal epilepsy using continuous EEG-correlated fMRI. Seizures were characterized by head turning to the left and clonic jerking of the left arm, suggesting a right frontal epileptogenic region.
Duncan, J.S., Hamandi, K., Laufs, H., Lemieux, L., Scott, C., Smith, S., Walker, M.C.   +6 more
core   +1 more source

Resolution of generalized tonic seizures following focal ablative or resective surgery

Epileptic Disorders, EarlyView.
Abstract Objective Focal brain lesions may underlie generalized tonic seizures, as seen in Lennox–Gastaut syndrome, by engaging bilateral neural networks. However, this seizure type is often not considered surgically remediable. Here, we describe the resolution of apparent electroclinically classic generalized tonic seizures in children originating ...
Sem L. Kampman, Itay Tokatly Latzer, Aaron E. L. Warren, Jurriaan M. Peters   +3 more
wiley   +1 more source

Video-EEG long term monitoring as a new service at Mater Dei Hospital [PDF]

, 2016
Introduction: Video-EEG long-term monitoring (LTM) was introduced into Mater Dei Hospital (MDH) in May 2012. The audit aims to evaluate LTM in terms of diagnostic outcomes and impact on patient management.
Aquilina, Josanne, Galea, Bernard, Gravino, Gilbert, Soler, Doriette, Vella, Norbert   +4 more
core  

EEG–fMRI of idiopathic and secondarily generalized epilepsies [PDF]

, 2006
We used simultaneous EEG and functional MRI (EEG–fMRI) to study generalized spike wave activity (GSW) in idiopathic and secondary generalized epilepsy (SGE).
Duncan, J.S., Fish, D.R., Friston, K., Hamandi, K., Laufs, H., Lemieux, L., Liston, A., Salek-Haddadi, A.   +7 more
core   +1 more source

Electro‐clinical features of Mowat–Wilson syndrome: A retrospective study of 31 children in mainland China

Epileptic Disorders, EarlyView.
Abstract Objective To summarize the electro‐clinical and genetic characteristics of children with Mowat–Wilson syndrome (MWS). Methods This study is a hospital‐based case series analyzing clinical data from 31 pediatric patients with MWS and epilepsy treated at Peking University First Hospital between June 2020 and December 2024.
Yi Ju, Tao‐yun Ji
wiley   +1 more source

Role of membrane potential fluctuations to the criticality of neuronal avalanche activity [PDF]

, 2007
Experimental evidence for self-organised criticality (SOC) in non-conservative systems has recently been found in studies of rat cortical slices. The size distribution of observed neuronal avalanches has been attested to obey $3/2$ power-law scaling.
Juanico, Dr Dranreb Earl
core  

Mesial temporal lobe epilepsy with hippocampal sclerosis: Seizure, neuropsychological, and quality of life outcomes of 100 patients treated with trans‐anterior T1 selective amygdalohippocampectomy

Epileptic Disorders, EarlyView.
Abstract Objective For mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE with HS), laser interstitial thermal therapy has recently been increasingly used. At our institute, however, selective amygdalohippocampectomy by a trans‐anterior T1 subpial approach (trans‐anterior T1 SAH) has been used for MTLE with HS. Here, we examined the seizure,
Naotaka Usui, Hiroshi Ogawa, Akihiko Kondo, Kazumi Matsuda, Mitsuru Hashiguchi, Taro Okumura, Yuuki Ishida, Norihiko Kawaguchi, Takashi Matsudaira, Kentaro Tokumoto, Takuji Nishida, Katsumi Imai   +11 more
wiley   +1 more source