Results 211 to 220 of about 41,822 (309)

Roles of metabotropic glutamate receptor 5 in low [Mg²⁺]_o-induced interictal epileptiform activity in rat hippocampal slices. [PDF]

Korean J Physiol Pharmacol
Yang JS, Jang HJ, Sung KW, Rhie DJ, Yoon SH.   +4 more
europepmc   +1 more source

Clinical outcomes and learning curve of MRgLITT system for drug‐resistant epilepsy in China: A single‐center retrospective study

Epilepsia Open, EarlyView.
Abstract Objective Magnetic resonance‐guided laser interstitial thermal therapy (MRgLITT) is a minimally invasive technique that allows for real‐time magnetic resonance imaging (MRI) monitoring and precise ablation of epileptogenic lesions. This study reports our initial clinical experience with a domestically developed MRgLITT system in patients with ...
Sichang Chen, Yang Dai, Xiaotong Fan, Yihe Wang, Penghu Wei, Yongzhi Shan, Guoguang Zhao   +6 more
wiley   +1 more source

Semiology in spontaneous versus cortical stimulation‐induced seizures during SEEG: A within‐patient comparison study

Epilepsia Open, EarlyView.
Abstract Objective We aimed to study the concordance of seizure semiology in direct electrical stimulation‐induced seizures (SIS) compared to spontaneous seizures during stereoelectroencephalography (SEEG) and to report on patient‐level variables associated with habitual and atypical SIS.
Marai Mahizhnan, Stéphane Dufau, John Phamnguyen, Arash Kahrom, Donald Craig, Aileen McGonigal   +5 more
wiley   +1 more source

Transient Seizure Clusters and Epileptiform Activity Following Widespread Bilateral Hippocampal Interneuron Ablation. [PDF]

eNeuro
Dusing MR, LaSarge CL, Drake AW, Westerkamp GC, McCoy C, Hetzer SM, Kraus KL, Pedapati EV, Danzer SC.   +8 more
europepmc   +1 more source

Scalp fast oscillations detected by high‐density EEG as a noninvasive predictor of surgical outcome in temporal lobe epilepsy with hippocampal sclerosis

Epilepsia Open, EarlyView.
Abstract Objective To evaluate whether scalp oscillatory patterns—particularly scalp fast oscillations (SFOs) (>30 Hz) detected using 256‐channel high‐density EEG (HD‐EEG)—are associated with and can predict surgical outcomes in patients with drug‐resistant temporal lobe epilepsy with hippocampal sclerosis (TLE‐HS) undergoing anterior temporal ...
Pongsakorn Kongsakorn, Suda Jirasakuldej, Peerasit Treesuthacheep, Totsapol Surawattanawong, Chusak Limotai   +4 more
wiley   +1 more source

Emergent epileptiform activity in spinal sensory circuits drives ectopic bursting in afferent axons and sensory dysfunction after cord injury. [PDF]

Pain
Bryson M, Kloefkorn H, Idlett-Ali S, Carrasco DI, Noble DJ, Noble DJ, Martin K, Sawchuk MA, Au Yong N, Garraway SM, Hochman S.   +10 more
europepmc   +1 more source

Sialidosis type I: How to alleviate disabling myoclonic seizures?—A multicenter analysis of eight cases and review of the literature

Epilepsia Open, EarlyView.
Abstract Objective Sialidosis type I (ST‐1) is an autosomal‐recessive, very rare, progressive lysosomal storage disorder caused by pathogenic variants in NEU1. It is clinically characterized by progressive ataxia, myoclonic seizures (MS), bilateral tonic–clonic seizures (BTCS), and distinctive ophthalmological findings.
Janina Gburek‐Augustat, I‐Chun Lee, Marica Rubino, Vehap Topçu, Melissa Chavez‐Castillo, Shao Ching Tu, Marwan Shinawi, Isabel Alfradique‐Dunham, Manouela Valtcheva, Astrid Adarmes‐Gómez, Daniel Macias‐Garcia, Laura Laura Muñoz‐Delgado, Silvia Jesús, Pablo Mir, Andreas Merkenschlager, Antonietta Coppola   +15 more
wiley   +1 more source

Subclinical epileptiform activity in the Alzheimer continuum: association with disease, cognition and detection method. [PDF]

Alzheimers Res Ther
Nous A, Seynaeve L, Feys O, Wens V, De Tiège X, Van Mierlo P, Baroumand AG, Nieboer K, Allemeersch GJ, Mangelschots S, Michiels V, van der Zee J, Van Broeckhoven C, Ribbens A, Houbrechts R, De Witte S, Wittens MMJ, Bjerke M, Vanlersberghe C, Ceyssens S, Nagels G, Smolders I, Engelborghs S.   +22 more
europepmc   +1 more source

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

RNA Sequencing Demonstrates Ex Vivo Neocortical Transcriptomic Changes Induced by Epileptiform Activity in Male and Female Mice. [PDF]

eNeuro
Vaughan AJ, McMeekin LJ, Hine K, Stubbs IW, Codadu NK, Cockell S, Hill JT, Cowell R, Trevelyan AJ, Parrish RR.   +9 more
europepmc   +1 more source