Results 141 to 150 of about 12,577 (248)
IEEE Transactions on Neural Systems and Rehabilitation EngineeringElectroencephalography (EEG) based source localization (ESL) is a useful method to localize the epileptogenic zone in epilepsy surgery. However, previous techniques only perform 3-dimensional (3D) reconstruction, and do not conduct delineation on the ...
Jeongyoon Shin +6 more
doaj +1 more source
Epilepsia Open, EarlyView.Abstract Objective The integration of neurotechnology and artificial intelligence (AI) in epilepsy research has led to significant advancements in diagnosis, monitoring, and treatment. However, the impact of these innovations is often diminished by inadequate and inaccurate reporting, limiting their reproducibility and implementation.
Pedro F. Viana +6 more
wiley +1 more source
Frontiers in NeurologyIntroductionThis study investigated low-density scalp electrical source imaging of the ictal onset zone and interictal spike ripple high-frequency oscillation networks using source coherence maps in the pediatric epilepsy surgical workup.
Parnia Sadeghzadeh +8 more
doaj +1 more source
Network structure determines patterns of network reorganization during adult neurogenesis [PDF]
, 2009 New cells are generated throughout life and integrate into the hippocampus via the process of adult neurogenesis. Epileptogenic brain injury induces many structural changes in the hippocampus, including the death of interneurons and altered connectivity ...
Ben-Jacob, Eshel +4 more
core
Does having bad epilepsy make you a good surgical candidate? A number needed to treat analysis
Epilepsia Open, EarlyView.Abstract Epilepsy surgery is an established treatment for drug‐resistant epilepsy, offering a realistic prospect of seizure freedom in well‐selected candidates. However, surgery is sometimes offered to individuals with a low probability of seizure freedom when it is framed as potentially “life‐saving” on the basis of the elevated mortality associated ...
Sallie Baxendale +2 more
wiley +1 more source
Epilepsia Open, EarlyView.Abstract Objective Focal epilepsy is characterized by progressive cortical thinning, particularly within limbic structures; however, whether this atrophy reflects acquired seizure‐induced damage or shared genetic predisposition remains unresolved. Methods We integrated genome‐wide association study (GWAS) summary statistics from the ILAE Consortium ...
Dingyuan Zhang +9 more
wiley +1 more source
Epilepsia Open, EarlyView.Abstract Objective Expanded indications, diagnostic tools, and treatment options have transformed the landscape of modern pediatric epilepsy surgery. Published real‐world experiences from large surgical cohorts are still needed. To close this gap, we evaluated access, indications, treatment, and outcomes in a contemporary pediatric epilepsy surgery ...
John R. McLaren +12 more
wiley +1 more source
ILAE‐YES global webinar series: Integrating clinical and basic science in epilepsy research
Epilepsia Open, EarlyView.An ILAE‐YES global webinar series bridging basic and clinical epilepsy research inspired new research ideas in 80% of participants. Abstract Summary Bridging clinical and basic research is increasingly recognized as a priority in the epilepsy field, yet opportunities for integration remain limited by the time, space, and financial constraints of ...
Cecilie G. Nome +22 more
wiley +1 more source
Brain Pathology, EarlyView.Histopathological identification of subtle cortical architectural abnormalities in focal cortical dysplasia (FCD) resections remains challenging. We investigated if artificial intelligence (AI)‐based morphometric and spatial analysis of NeuN‐stained cortical sections could detect neuronal architectural disorganization in epilepsy resections, including ...
Andrew Cannon +9 more
wiley +1 more source
Clinical and Translational Medicine, Volume 16, Issue 5, May 2026.• Excitatory neurons and astrocytes show marked alterations in the single‐cell spatial transcriptomic atlas of epileptogenic cortex from patients with focal cortical dysplasia type I (FCDI). • The CBLN2high excitatory neuron subtype may be associated with neuronal hyperexcitability and cortical development in FCDI.
Yaqian Zhang +9 more
wiley +1 more source