Results 151 to 160 of about 108,868 (302)

Identification of broadly expressed nervous system‐related genes as effective RNAi targets in the brown marmorated stink bug, Halyomorpha halys

open access: yesPest Management Science, EarlyView.
Broadly expressed genes outperformed brain‐enriched neural targets as RNAi candidates in Halyomorpha halys. Microinjection of dsRNA targeting alpha‐soluble NSF attachment protein (Asnap) or Ras opposite protein (Rop) caused strong feeding suppression and near‐complete mortality, identifying them as promising targets for future oral or spray‐based RNAi ...
Nirakar Panda   +2 more
wiley   +1 more source

Evaluation of Potential Hormonal Activities of Ashwagandha (Withania somnifera)

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Ashwagandha is a widely used herb in traditional medicine systems, particularly Ayurveda. Despite its extensive tradition, growing concerns regarding its potential endocrinological effects have prompted scientific scrutiny. This review systematically evaluates the current preclinical, clinical, and case study evidence concerning AS's effects ...
Günter Vollmer, Thomas Brendler
wiley   +1 more source

An Outline of a Theory of Play

open access: yesSymbolic Interaction, EarlyView.
Play is often dismissed as trivial, yet it is a fundamental and adaptive aspect of human and mammalian life. This paper develops a sociological theory of play, treating it as a total social fact that spans biological, psychological, and social dimensions.
Seth Abrutyn
wiley   +1 more source

Climate‐Modulated Particle Toxicity: Acute Exposure to an Environmentally Informed Microplastic Mixture Induces Sex‐Dependent Systemic Reorganization in Swiss Mice

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Microplastic (MP) pollution is widely recognized as an emerging environmental threat. Yet, most studies still rely on controlled experimental conditions that poorly reflect environmental complexity, potentially underestimating risks under realistic scenarios, particularly during short‐term exposures. Here, we tested whether acute oral exposure
Guilherme Malafaia   +5 more
wiley   +1 more source

Preoperative caudal blocks associated with decreased cumulative opioid requirements compared to postoperative caudal blocks in pediatric urologic surgery

open access: yesUroPrecision, EarlyView.
Abstract Background Caudal blocks (CB) are a cornerstone of pediatric urologic surgery, providing effective analgesia while mitigating potential neurotoxicity associated with general anesthesia and opioids. However, the optimal timing of CB—preoperative versus postoperative—remains controversial.
Jordan L. Mendelson   +11 more
wiley   +1 more source

What Is the Safe and Optimal Dosing of Epinephrine in Tumescent Solution for Pediatric Burn Patients? [PDF]

open access: yesPlast Reconstr Surg Glob Open
Subramaniam N   +3 more
europepmc   +1 more source

Penile intracavernosal injection of succinylcholine for laryngospasm management during hypospadias repair

open access: yesUroPrecision, EarlyView.
Abstract Background Laryngospasm is a serious anesthetic complication that can lead to acute airway obstruction and hypoxemia. Standard management involves deepening anesthesia and administering succinylcholine intravenously (IV) or intramuscularly (IM). However, if IV access is lost or IM drug delivery is too slow, alternative routes are required.
Diego R. Álvarez Vega   +6 more
wiley   +1 more source

Effect of butorphanol in combination with xylazine during castration of calves: A randomised trial under field conditions

open access: yesVeterinary Record, EarlyView.
Abstract Background In horses, cats and dogs, the opioid butorphanol has been proven effective in management of visceral pain and for peri‐ and postoperative pain relief. The aim of this study was to evaluate physiological responses and indicators of noxious stimuli when adding butorphanol to xylazine for sedation of bull calves during surgical ...
Axel Sannö   +3 more
wiley   +1 more source

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