Results 11 to 20 of about 180,597 (336)
Background Obtaining vascular access can be challenging during resuscitation following cardiac arrest, and it is particularly difficult and time-consuming in paediatric patients.
Daesung Lim +5 more
doaj +1 more source
Epinephrine: The Drug of Choice for Anaphylaxis--A Statement of the World Allergy Organization
Anaphylaxis is an acute and potentially lethal multisystem allergic reaction. Most consensus guidelines for the past 30 years have held that epinephrine is the drug of choice and the first drug that should be administered in acute anaphylaxis. Some state
Stephen F. Kemp +2 more
doaj +1 more source
Catecholamine stress alters neutrophil trafficking and impairs wound healing by β2-adrenergic receptor-mediated upregulation of IL-6. [PDF]
Stress-induced hormones can alter the inflammatory response to tissue injury; however, the precise mechanism by which epinephrine influences inflammatory response and wound healing is not well defined.
Byrne, Barbara A +7 more
core +2 more sources
Arrhythmia induction using isoproterenol or epinephrine during electrophysiology study for supraventricular tachycardia [PDF]
Background Electrophysiology study (EPS) is an important part of the diagnosis and workup for supraventricular tachycardia (SVT). Provocative medications are used to induce arrhythmias, when they are not inducible at baseline. The most common medication
Padanilam, Benzy J. +4 more
core +1 more source
Evaluation of Timing and Route of Epinephrine in a Neonatal Model of Asphyxial Arrest
BackgroundEpinephrine administered by low umbilical venous catheter (UVC) or endotracheal tube (ETT) is indicated in neonates who fail to respond to positive pressure ventilation and chest compressions at birth.
Payam Vali +11 more
doaj +1 more source
Patient perceptions of epinephrine auto-injectors: Exploring barriers to use [PDF]
Background: In recent years, government initiatives have proposed that patient self-care should serve as a key resource in response to the anticipated increase in global demand for health care.
Barnett, J +3 more
core +1 more source
The 7th edition of the Textbook of Neonatal Resuscitation recommends administration of epinephrine via an umbilical venous catheter (UVC) inserted 2–4 cm below the skin, followed by a 0.5-mL to 1-mL flush for severe bradycardia despite effective ...
Deepika Sankaran +19 more
doaj +1 more source
Functional selectivity of GPCR-directed drug action through location bias. [PDF]
G-protein-coupled receptors (GPCRs) are increasingly recognized to operate from intracellular membranes as well as the plasma membrane. The β 2 -adrenergic GPCR can activate G s -linked cyclic AMP (G s -cAMP) signaling from endosomes.
Conti, Marco +6 more
core +3 more sources
Obstructive sleep apnea (OSA) is an independent risk factor for cardiovascular disease. While intermittent hypoxia (IH) and catecholamine release play an important role in this increased risk, the mechanisms are incompletely understood.
Rengul Cetin-Atalay +9 more
doaj +1 more source
NaCl transport stimulates prostaglandin release in cultured renal epithelial (MDCK) cells [PDF]
Prostaglandins (PGs) can modulate a variety of renal functions, including Na+ and Cl- reabsorption. However, it is not known if a direct interdependence exists between PG synthesis and transport activity. The present study was done to find out whether or
Bauer, C. +3 more
core +1 more source

