Catecholamine stress alters neutrophil trafficking and impairs wound healing by β2-adrenergic receptor-mediated upregulation of IL-6. [PDF]
, 2014 Stress-induced hormones can alter the inflammatory response to tissue injury; however, the precise mechanism by which epinephrine influences inflammatory response and wound healing is not well defined.
Byrne, Barbara A +7 more
core +2 more sources
BMC Cardiovascular Disorders, 2021 Background Obtaining vascular access can be challenging during resuscitation following cardiac arrest, and it is particularly difficult and time-consuming in paediatric patients.
Daesung Lim +5 more
doaj +1 more source
Arrhythmia induction using isoproterenol or epinephrine during electrophysiology study for supraventricular tachycardia [PDF]
, 2018 Background Electrophysiology study (EPS) is an important part of the diagnosis and workup for supraventricular tachycardia (SVT). Provocative medications are used to induce arrhythmias, when they are not inducible at baseline. The most common medication
Padanilam, Benzy J. +4 more
core +1 more source
Evaluation of Timing and Route of Epinephrine in a Neonatal Model of Asphyxial Arrest
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017 BackgroundEpinephrine administered by low umbilical venous catheter (UVC) or endotracheal tube (ETT) is indicated in neonates who fail to respond to positive pressure ventilation and chest compressions at birth.
Payam Vali +11 more
doaj +1 more source
Patient perceptions of epinephrine auto-injectors: Exploring barriers to use [PDF]
, 2013 Background: In recent years, government initiatives have proposed that patient self-care should serve as a key resource in response to the anticipated increase in global demand for health care.
Barnett, J +3 more
core +1 more source
Tumescent Injections in Subcutaneous Pig Tissue Disperse Fluids Volumetrically and Maintain Elevated Local Concentrations of Additives for Several Hours, Suggesting a Treatment for Drug Resistant Wounds. [PDF]
, 2020 PurposeBolus injection of fluid into subcutaneous tissue results in accumulation of fluid at the injection site. The fluid does not form a pool. Rather, the injection pressure forces the interstitial matrix to expand to accommodate the excess fluid in ...
Dunn, James CY +5 more
core +2 more sources
International consensus on (ICON) anaphylaxis [PDF]
, 2014 ICON: Anaphylaxis provides a unique perspective on the principal evidence-based anaphylaxis guidelines developed and published independently from 2010 through 2014 by four allergy/immunology organizations.
Alvarez-Twose +137 more
core +3 more sources
Children, 2021 The 7th edition of the Textbook of Neonatal Resuscitation recommends administration of epinephrine via an umbilical venous catheter (UVC) inserted 2–4 cm below the skin, followed by a 0.5-mL to 1-mL flush for severe bradycardia despite effective ...
Deepika Sankaran +19 more
doaj +1 more source
Who needs epinephrine? Anaphylaxis, auto-injectors, and parachutes [PDF]
, 2023 International guidelines stipulate that intramuscular (IM) epinephrine (adrenaline) is the first-line treatment for anaphylaxis, with an established good safety profile.
Dribin, TE, Turner, P, Waserman, S
core +1 more source
Pharmacokinetics of epinephrine in patients with septic shock: modelization and interaction with endogenous neurohormonal status [PDF]
, 2009 Introduction In septic patients, an unpredictable response to epinephrine may be due to pharmacodynamic factors or to non-linear pharmacokinetics. The purpose of this study was to investigate the pharmacokinetics of epinephrine and its determinants in ...
C. Faisy +6 more
core +3 more sources