Results 11 to 20 of about 180,597 (336)

The effect of high-dose intramuscular epinephrine on the recovery of spontaneous circulation in an asphyxia‐induced cardiac arrest rat model

open access: yesBMC Cardiovascular Disorders, 2021
Background Obtaining vascular access can be challenging during resuscitation following cardiac arrest, and it is particularly difficult and time-consuming in paediatric patients.
Daesung Lim   +5 more
doaj   +1 more source

Epinephrine: The Drug of Choice for Anaphylaxis--A Statement of the World Allergy Organization

open access: yesWorld Allergy Organization Journal, 2008
Anaphylaxis is an acute and potentially lethal multisystem allergic reaction. Most consensus guidelines for the past 30 years have held that epinephrine is the drug of choice and the first drug that should be administered in acute anaphylaxis. Some state
Stephen F. Kemp   +2 more
doaj   +1 more source

Catecholamine stress alters neutrophil trafficking and impairs wound healing by β2-adrenergic receptor-mediated upregulation of IL-6. [PDF]

open access: yes, 2014
Stress-induced hormones can alter the inflammatory response to tissue injury; however, the precise mechanism by which epinephrine influences inflammatory response and wound healing is not well defined.
Byrne, Barbara A   +7 more
core   +2 more sources

Arrhythmia induction using isoproterenol or epinephrine during electrophysiology study for supraventricular tachycardia [PDF]

open access: yes, 2018
Background Electrophysiology study (EPS) is an important part of the diagnosis and workup for supraventricular tachycardia (SVT). Provocative medications are used to induce arrhythmias, when they are not inducible at baseline. The most common medication
Padanilam, Benzy J.   +4 more
core   +1 more source

Evaluation of Timing and Route of Epinephrine in a Neonatal Model of Asphyxial Arrest

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundEpinephrine administered by low umbilical venous catheter (UVC) or endotracheal tube (ETT) is indicated in neonates who fail to respond to positive pressure ventilation and chest compressions at birth.
Payam Vali   +11 more
doaj   +1 more source

Patient perceptions of epinephrine auto-injectors: Exploring barriers to use [PDF]

open access: yes, 2013
Background: In recent years, government initiatives have proposed that patient self-care should serve as a key resource in response to the anticipated increase in global demand for health care.
Barnett, J   +3 more
core   +1 more source

Effect of a Larger Flush Volume on Bioavailability and Efficacy of Umbilical Venous Epinephrine during Neonatal Resuscitation in Ovine Asphyxial Arrest

open access: yesChildren, 2021
The 7th edition of the Textbook of Neonatal Resuscitation recommends administration of epinephrine via an umbilical venous catheter (UVC) inserted 2–4 cm below the skin, followed by a 0.5-mL to 1-mL flush for severe bradycardia despite effective ...
Deepika Sankaran   +19 more
doaj   +1 more source

Functional selectivity of GPCR-directed drug action through location bias. [PDF]

open access: yes, 2017
G-protein-coupled receptors (GPCRs) are increasingly recognized to operate from intracellular membranes as well as the plasma membrane. The β 2 -adrenergic GPCR can activate G s -linked cyclic AMP (G s -cAMP) signaling from endosomes.
Conti, Marco   +6 more
core   +3 more sources

Intermittent hypoxia inhibits epinephrine-induced transcriptional changes in human aortic endothelial cells

open access: yesScientific Reports, 2022
Obstructive sleep apnea (OSA) is an independent risk factor for cardiovascular disease. While intermittent hypoxia (IH) and catecholamine release play an important role in this increased risk, the mechanisms are incompletely understood.
Rengul Cetin-Atalay   +9 more
doaj   +1 more source

NaCl transport stimulates prostaglandin release in cultured renal epithelial (MDCK) cells [PDF]

open access: yes, 1986
Prostaglandins (PGs) can modulate a variety of renal functions, including Na+ and Cl- reabsorption. However, it is not known if a direct interdependence exists between PG synthesis and transport activity. The present study was done to find out whether or
Bauer, C.   +3 more
core   +1 more source

Home - About - Disclaimer - Privacy