Results 231 to 240 of about 183,438 (323)

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

Epinephrine nasal spray for the treatment of anaphylaxis: perspectives in pediatrics. [PDF]

open access: yesCurr Opin Allergy Clin Immunol
Crescioli G   +6 more
europepmc   +1 more source

Homo sapiens, industrialisation and the environmental mismatch hypothesis

open access: yesBiological Reviews, EarlyView.
ABSTRACT For the vast majority of the evolutionary history of Homo sapiens, a range of natural environments defined the parameters within which selection shaped human biology. Although human‐induced alterations to the terrestrial biosphere have been evident for over 10,000 years, the pace and scale of change has accelerated dramatically since the onset
Daniel P. Longman, Colin N. Shaw
wiley   +1 more source

Adrenaline Auto‐Injector Prescribing in Primary Care in England: An Analysis of Non‐Standard Dosing

open access: yesClinical &Experimental Allergy, EarlyView.
Investigation into English primary care prescription data reveals that patients are receiving non‐standard doses of adrenaline auto‐injectors at all ages and across the whole of England. Guidance must be updated to include better dose‐switching procedures. At a minimum, patients aged 14 and older should be switched to 300 μg devices.
Louise J. Michaelis   +3 more
wiley   +1 more source

Comparative evaluation of 2% mepivacaine and 2% lidocaine for inferior alveolar nerve block: a double-blind randomized clinical trial. [PDF]

open access: yesBMC Oral Health
Panya S   +7 more
europepmc   +1 more source

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