Results 21 to 30 of about 144,286 (143)

Association of Prehospital Epinephrine Administration With Survival Among Patients With Traumatic Cardiac Arrest Caused By Traffic Collisions

Scientific Reports, 2019
For traumatic cardiac arrest (TCA), the effect of prehospital epinephrine administration was unclear. The aim of this study was to evaluate the relationship between prehospital epinephrine administration and survival in patients with TCA caused by ...
Makoto Aoki, Toshikazu Abe, Kiyohiro Oshima   +2 more
doaj   +1 more source

A systematic review of epinephrine stability and sterility with storage in a syringe

Allergy, Asthma & Clinical Immunology, 2019
Background Epinephrine is a lifesaving medication in the treatment of anaphylaxis. Epinephrine auto-injectors are the preferred method of epinephrine administration, but are not universally available or affordable.
Hannah G. Parish, Jacquelyn R. Morton, Julie C. Brown   +2 more
doaj   +1 more source

Identifying Ligand Binding Conformations of the β2-Adrenergic Receptor by Using Its Agonists as Computational Probes [PDF]

, 2011
Recently available G-protein coupled receptor (GPCR) structures and biophysical studies suggest that the difference between the effects of various agonists and antagonists cannot be explained by single structures alone, but rather that the conformational
Ashley M. Buckle, B Isin, B Isin, B Isin, Basak Isin, BK Kobilka, BK Kobilka, C Gales, CD Strader, CD Strader, CD Strader, DL Farrens, DM Rosenbaum, DM Rosenbaum, DS Han, E Reiter, FZ Chung, G Liapakis, G Liapakis, G Swaminath, G Swaminath, Guillermina Estiu, GV Paolini, HW Choe, I Bahar, JA Javitch, JC Phillips, JE Olsson, JJ Liu, JP Overington, K Palczewski, K Wieland, KA Reynolds, L Shi, LM Luttrell, LS Barak, M Arakawa, M Azzi, MA Yildirim, MP Bokoch, MS Johnson, O Fritze, Olaf Wiest, P Ghanouni, PG Strange, R Nygaard, R Seifert, RA Friesner, RA Friesner, RO Dror, S Ahuja, S Bhattacharya, S Ludeke, SA Green, SG Rasmussen, SG Rasmussen, SG Rasmussen, T Palanche, TD Romo, U Gether, V Cherezov, X Deupi, X Yao, X Zhang, Zoltán N. Oltvai   +64 more
core   +3 more sources

NaCl transport stimulates prostaglandin release in cultured renal epithelial (MDCK) cells [PDF]

, 1986
Prostaglandins (PGs) can modulate a variety of renal functions, including Na+ and Cl- reabsorption. However, it is not known if a direct interdependence exists between PG synthesis and transport activity. The present study was done to find out whether or
Bauer, C., Brown, C. D., Kurtz, Armin, Pfeilschifter, J.   +3 more
core   +1 more source

Epinephrine during resuscitation of traumatic cardiac arrest and increased mortality: a post hoc analysis of prospective observational study

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2019
Background The beneficial effect of epinephrine during resuscitation from out-of-hospital cardiac arrest (OHCA) has been inconclusive, and potential harm has been suggested, particularly in trauma victims.
Ryo Yamamoto, Masaru Suzuki, Kei Hayashida, Jo Yoshizawa, Atsushi Sakurai, Nobuya Kitamura, Takashi Tagami, Taka-aki Nakada, Munekazu Takeda, Junichi Sasaki, on behalf of the SOS-KANTO 2012 Study Group   +10 more
doaj   +1 more source

Functional selectivity of GPCR-directed drug action through location bias. [PDF]

, 2017
G-protein-coupled receptors (GPCRs) are increasingly recognized to operate from intracellular membranes as well as the plasma membrane. The β 2 -adrenergic GPCR can activate G s -linked cyclic AMP (G s -cAMP) signaling from endosomes.
Conti, Marco, Huang, Bo, Irannejad, Roshanak, Mika, Delphine, Pessino, Veronica, von Zastrow, Mark, Wedegaertner, Philip B.   +6 more
core   +3 more sources

Epinephrine in Anaphylaxis: Preclinical Study of Pharmacokinetics after Sublingual Administration of Taste-Masked Tablets for Potential Pediatric Use

Pharmaceutics, 2018
Epinephrine is a life-saving treatment in anaphylaxis. In community settings, a first-aid dose of epinephrine is injected from an auto-injector (EAI). Needle phobia highly contributes to EAI underuse, leading to fatalities—especially in children. A novel
Ousama Rachid, Mutasem Rawas-Qalaji, Keith J. Simons   +2 more
doaj   +1 more source

The Dogma of Tissue Ischemia with Local Anesthetic and Epinephrine Use [PDF]

, 2022
Epinephrine is often combined with Lidocaine for local anesthetic use as it improves the duration and quality of Lidocaine and promotes wound hemostasis.1-2 Despite these benefits, epinephrine has been historically contraindicated from being injected ...
Morrissey, Laura
core   +1 more source

A Case Report of Angioedema and Anaphylactic Shock Induced by Ingestion of Polyethylene Glycol [PDF]

, 2020
Introduction: We report one of few documented cases of a severe anaphylactic reaction with angioedema to polyethylene glycol (PEG).Case Report: The patient presented 30 minutes after onset of his symptoms and quickly developed hypoxia and hypotension ...
Osborn, Lesley, Rossi, Amy
core  

Epinephrine and Cardiac Arrest: The Catch-22 [PDF]

, 2023
Epinephrine has been a standard of care treatment for cardiac arrest for the last century; however, the use of epinephrine began without a significant amount of research.
Shaina Friedman
core   +1 more source