NaCl transport stimulates prostaglandin release in cultured renal epithelial (MDCK) cells [PDF]
Prostaglandins (PGs) can modulate a variety of renal functions, including Na+ and Cl- reabsorption. However, it is not known if a direct interdependence exists between PG synthesis and transport activity. The present study was done to find out whether or
Bauer, C. +3 more
core +1 more source
Identifying Ligand Binding Conformations of the β2-Adrenergic Receptor by Using Its Agonists as Computational Probes [PDF]
Recently available G-protein coupled receptor (GPCR) structures and biophysical studies suggest that the difference between the effects of various agonists and antagonists cannot be explained by single structures alone, but rather that the conformational
Ashley M. Buckle +64 more
core +3 more sources
Chronic toxicity of inhaled thymol in lungs and respiratory tracts in mouse model. [PDF]
Epinephrine HFA (Primatene® Mist) is a newly formulated asthma metered dose inhaler developed to replace the previous Primatene® Mist CFC. The formulation of Epinephrine HFA contains thymol, a substance recognized to be safe by the FDA.
Luo, Mary Z +3 more
core +2 more sources
For traumatic cardiac arrest (TCA), the effect of prehospital epinephrine administration was unclear. The aim of this study was to evaluate the relationship between prehospital epinephrine administration and survival in patients with TCA caused by ...
Makoto Aoki +2 more
doaj +1 more source
A Cost Analysis of Carpal Tunnel Release Surgery Performed Wide Awake versus under Sedation. [PDF]
BACKGROUND: Hand surgery under local anesthesia only has been used more frequently in recent years. The purpose of this study was to compare perioperative time and cost for carpal tunnel release performed under local anesthesia ( wide-awake local ...
Al Youha +23 more
core +2 more sources
Background The beneficial effect of epinephrine during resuscitation from out-of-hospital cardiac arrest (OHCA) has been inconclusive, and potential harm has been suggested, particularly in trauma victims.
Ryo Yamamoto +10 more
doaj +1 more source
Organic Cation Transporter 3: A Cellular Mechanism Underlying Rapid, Non-Genomic Glucocorticoid Regulation of Monoaminergic Neurotransmission, Physiology, and Behavior [PDF]
Corticosteroid hormones act at intracellular glucocorticoid receptors (GR) and mineralocorticoid receptors (MR) to alter gene expression, leading to diverse physiological and behavioral responses.
Gasser, Paul J., Lowry, Christopher A.
core +2 more sources
A Case Report of Angioedema and Anaphylactic Shock Induced by Ingestion of Polyethylene Glycol [PDF]
Introduction: We report one of few documented cases of a severe anaphylactic reaction with angioedema to polyethylene glycol (PEG).Case Report: The patient presented 30 minutes after onset of his symptoms and quickly developed hypoxia and hypotension ...
Osborn, Lesley, Rossi, Amy
core
A survey study of index food‐related allergic reactions and anaphylaxis management [PDF]
Background: Initial food‐allergic reactions are often poorly recognized and under‐treated. Methods: Parents of food‐allergic children were invited to complete an online questionnaire, designed with Kids with Food Allergies Foundation , about their
Green, Todd D. +4 more
core +1 more source
Epinephrine is a life-saving treatment in anaphylaxis. In community settings, a first-aid dose of epinephrine is injected from an auto-injector (EAI). Needle phobia highly contributes to EAI underuse, leading to fatalities—especially in children. A novel
Ousama Rachid +2 more
doaj +1 more source

