Results 51 to 60 of about 183,438 (323)

Elevator‐Like Hollow Channels in Porous Scaffolds Accelerate Vascularized Bone Regeneration via NETs‐Fibrin‐Mediated Macrophage Recruitment

Advanced Science, EarlyView.
This study demonstrates that how hollow‐channel scaffolds promote vascularized bone regeneration via an immunomodulatory mechanism. The channel structures facilitate the formation of a neutrophil extracellular traps‐fibrin scaffold that recruits vascular endothelial growth factor A (VEGF‐A)‐secreting M2 macrophages to drive angiogenesis. Combining this
Guifang Wang, Rongpu Liu, Huijing Ma, Shuhan Duan, Guangzheng Yang, LingXi Meng, Yuqin Qiao, Dongqiang Song, Wenjie Zhang   +8 more
wiley   +1 more source

Association of prehospital advanced airway and epinephrine with survival in patients with out-of-hospital cardiac arrest

Scientific Reports, 2023
Survival benefits of prehospital advanced airway and epinephrine in out-of-hospital cardiac arrest (OHCA) patients are controversial, but few studies evaluated this together. This study evaluated association of prehospital advanced airway and epinephrine
Sejoong Ahn, Bo-Yeong Jin, Hanjin Cho, Sungwoo Moon, Young-Duck Cho, Jong-Hak Park   +5 more
doaj   +1 more source

Uncovering the Lipid Interface in Neurotransmission: Single Molecule Measurements of Neurotransmitters Interacting with Membranes Reveal Species Dependent Membrane Binding

Advanced Science, EarlyView.
Using single‐molecule whispering gallery mode sensors, neurotransmitter‐specific membrane binding signatures are measured that reveal intrinsically distinct interaction kinetics and orientations on a lipid membrane. Abstract Neurotransmitters (NTs) have traditionally been understood to act via aqueous‐phase receptor binding, but growing evidence ...
Thomas L. Derrien, Aneeth Kakkanattu Arunkumar, Rosalind Cross, Emilie Sunnucks, Frank Vollmer   +4 more
wiley   +1 more source

Intramuscular versus intravenous epinephrine administration in a pediatric porcine model of cardiopulmonary resuscitation

Resuscitation Plus
Background: American Heart Association Pediatric Life Support guidelines recommend epinephrine administration via intravenous (IV) or intraosseous (IO) route, with endotracheal (ET) administration admissible in the absence of IV/IO access.
Megan O’Reilly, Janice A. Tijssen, Tze-Fun Lee, Marwa Ramsie, Po-Yin Cheung, Georg M. Schmölzer   +5 more
doaj   +1 more source

Impact of epinephrine administration frequency in out-of-hospital cardiac arrest patients: a retrospective analysis in a tertiary hospital setting

Journal of International Medical Research, 2019
Introduction Epinephrine is recommended for patients with out-of-hospital cardiac arrest (OHCA). However, whether epinephrine improves or adversely affects OHCA outcomes is controversial.
Mohammed A. Al-Mulhim, Mohammed S. Alshahrani, Laila Perlas Asonto, Ahmad Abdulhady, Talal M. Almutairi, Mariam Hajji, Mohammed A. Alrubaish, Khalid N. Almulhim, Mariam H. Al-Sulaiman, Layla B. Al-Qahtani   +9 more
doaj   +1 more source

Molecular Profiling of Genes Associated With Methylphenidate Pathway Therapy and Discovery of New Variants in Amazonian Amerindian Populations

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT In Attention Deficit Hyperactivity Disorder (ADHD), methylphenidate is one of the most widely used drugs, in which patient response significantly impacts prognosis. This study aimed to characterize the molecular profile of 10 genes associated with methylphenidate therapy.
Aline Pasquini Santos, Tatiane Carinta de Souza, Kaio Evandro Cardoso Aguiar, Ana Caroline Alves da Costa, Natasha Monte, Juliana Carla Gomes Rodrigues, Giovanna Gilioli da Costa Nunes, Rita de Cássia Calderaro Coelho, Ândrea Ribeiro‐dos‐Santos, André Maurício Ribeiro dos Santos, Sandro José de Souza, Sidney Emanuel Batista dos Santos, Rommel Mario Rodriguez Burbano, Marianne Rodrigues Fernandes, Ney Pereira Carneiro dos Santos   +14 more
wiley   +1 more source

Myocardial dysfunction after out-of-hospital cardiac arrest: predictors and prognostic implications. [PDF]

, 2018
We aim to determine the incidence of early myocardial dysfunction after out-of-hospital cardiac arrest, risk factors associated with its development, and association with outcome.
Gaieski, David Foster, Grossestreuer, Anne Victoria, Johnson, Nicholas James, Perman, Sarah Muirhead, Ramjee, Vimal, Yao, Yuan   +5 more
core   +1 more source

Efficacy of Local Bupivacaine Injection of Postoperative Pain in Endoscopic Sinus Surgery

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Regional anesthesia is effective in alleviating postoperative pain and reducing the requirement for systemic pain medications. However, optimal postoperative pain management in endoscopic sinus surgery (ESS) remains challenging.
Wiracha Leewannapasai, Navarat Tangbumrungtham, Kanokporn Sarsitthithum, Kangsadarn Tanjararak, Boonsam Roongpuvapaht   +4 more
wiley   +1 more source

Use of Epinephrine in Cardiac Arrest: Advances and Future Challenges

Medicina
Epinephrine is the most common medication used in cardiac arrest. Although the medication has been a mainstay of treatment over the last century, the utility and efficacy of epinephrine has been re-evaluated in recent years.
Caitlin A. Williams, Hannah E. Fairley, Quincy K. Tran, Ali Pourmand   +3 more
doaj   +1 more source

Vasopressin and epinephrine versus epinephrine in management of patients with cardiac arrest: a meta-analysis [PDF]

, 2010
Objective. A combination of vasopressin and epinephrine may be more effective than epinephrine alone in cardiopulmonary resuscitation (CPR), but evidence is lacking to make clinical recommendations. This meta-analysis compares the efficacy of vasopressin
DONG-PING WANG, HUI LI, XI-FU WANG, XIAO-LI JING, XIAO-XING LIAO, XIN LI, YAN XIONG   +6 more
core   +1 more source